DRUG INTERACTIONS
... decreasing the metabolism and increasing the plasma concentration of the antipsychotic. This increases the risk of seizures. Alternatively, seizures may occur in people with epilepsy as a result of decreased plasma concentration of an anti-epileptic owing to enzyme induction. For instance, St John’s ...
... decreasing the metabolism and increasing the plasma concentration of the antipsychotic. This increases the risk of seizures. Alternatively, seizures may occur in people with epilepsy as a result of decreased plasma concentration of an anti-epileptic owing to enzyme induction. For instance, St John’s ...
CI Drugs 2
... nervous system and slow down brain activity. Impaired co-ordination, balance and judgment are common. Higher doses can lead progressively to drowsiness, vomiting, coma and even death. Examples: Volatile substances or sniffable substances (eg glues, gases, aerosols) Alcohol Tranquillisers GHB ( ...
... nervous system and slow down brain activity. Impaired co-ordination, balance and judgment are common. Higher doses can lead progressively to drowsiness, vomiting, coma and even death. Examples: Volatile substances or sniffable substances (eg glues, gases, aerosols) Alcohol Tranquillisers GHB ( ...
MDMA WTR205 - WordPress.com
... of serotonin into the synaps. This significantly increases serotonin receptor binding. This increased receptor activity leads to significant changes in the brain electrical firing and is primarily responsible for the experience you get such as empathy, happiness, increased sociableness, enhanced sen ...
... of serotonin into the synaps. This significantly increases serotonin receptor binding. This increased receptor activity leads to significant changes in the brain electrical firing and is primarily responsible for the experience you get such as empathy, happiness, increased sociableness, enhanced sen ...
Pharmacology introduction Lecture three Dr. nahlah 21-10
... 2. Irreversible which is usually long-lasting for new enzyme synthesis, e.g., irreversible anticholinesterases. Action on specific receptors (Drug Receptor Interactions): receptors are macromolecular protein structures present on cell membrane or within the cell (cytoplasmic or nuclear) that react s ...
... 2. Irreversible which is usually long-lasting for new enzyme synthesis, e.g., irreversible anticholinesterases. Action on specific receptors (Drug Receptor Interactions): receptors are macromolecular protein structures present on cell membrane or within the cell (cytoplasmic or nuclear) that react s ...
Some Specific Info on Drugs used in Lab
... inhibition of the synthesis of prostaglandins and possibly inhibition of the synthesis or actions of other substances, which sensitize pain receptors to mechanical or chemical stimulation. Flunixin may act peripherally in inflamed tissue, probably by inhibiting the enzyme cyclooxygenase to decrease ...
... inhibition of the synthesis of prostaglandins and possibly inhibition of the synthesis or actions of other substances, which sensitize pain receptors to mechanical or chemical stimulation. Flunixin may act peripherally in inflamed tissue, probably by inhibiting the enzyme cyclooxygenase to decrease ...
Variability in Drug Response 2
... Pharmaceutical interactions often occur before a drug is given to the patient. Chemical interactions can occur because of acid base rxns, oxidation-reduction, salt formation, hydrolysis, or epimerization (change in the conformation of a compound). An example is thiopental and rocuronium forming a pr ...
... Pharmaceutical interactions often occur before a drug is given to the patient. Chemical interactions can occur because of acid base rxns, oxidation-reduction, salt formation, hydrolysis, or epimerization (change in the conformation of a compound). An example is thiopental and rocuronium forming a pr ...
Psychoactive plant species - Journal List
... prohibited in Poland. The tables at the end of the article contains information about expected psychoactive effects, psychic and somatic side effects which can occur after intake of the plants products. Plant species description Argyreia nervosa- Hawaiian Baby Woodrose is native to the Eastern India ...
... prohibited in Poland. The tables at the end of the article contains information about expected psychoactive effects, psychic and somatic side effects which can occur after intake of the plants products. Plant species description Argyreia nervosa- Hawaiian Baby Woodrose is native to the Eastern India ...
Snyder, Solomon H. - The Tanner Lectures on Human Values
... Here scientists and politicians come into conflict. Scientists value more than anything else their freedom of inquiry. The best scientists will not tolerate even the faintest hint of direction from administrators identifying for them what should be the “bottom line” of their research. The scientists ...
... Here scientists and politicians come into conflict. Scientists value more than anything else their freedom of inquiry. The best scientists will not tolerate even the faintest hint of direction from administrators identifying for them what should be the “bottom line” of their research. The scientists ...
Unit 4 Lecture: States of Consciousness
... tolerance: phenomenon whereby higher doses of a drug are required to produce its original effects or to prevent withdrawal symptoms withdrawal: unpleasant physical or psychological effects that follow the discontinuance of a dependence-producing substance abuse: a pattern of compulsive drug taking t ...
... tolerance: phenomenon whereby higher doses of a drug are required to produce its original effects or to prevent withdrawal symptoms withdrawal: unpleasant physical or psychological effects that follow the discontinuance of a dependence-producing substance abuse: a pattern of compulsive drug taking t ...
AZ compound details for MRC Asset Sharing Sept 2016
... liabilities in vivo. Selectivity was >100-fold in a panel of 160 other receptors, ion channels and enzymes, with the closest secondary pharmacology target being melatonin MT1 receptor antagonism (IC50 of 126nM). AZD7325 also potentiated native GABA responses in neurones prepared from the rat prefron ...
... liabilities in vivo. Selectivity was >100-fold in a panel of 160 other receptors, ion channels and enzymes, with the closest secondary pharmacology target being melatonin MT1 receptor antagonism (IC50 of 126nM). AZD7325 also potentiated native GABA responses in neurones prepared from the rat prefron ...
Drug Safety in the Elderly
... • Reduced amount of water in the body -fat soluble drugs remain longer in the body with prolonged effects – of importance for some sedatives and anxiolytics • Reduced kidney function - decreased excretion of some cardiovascular drugs, some antibiotics, diabetic drugs, antiinflammatory drugs – need t ...
... • Reduced amount of water in the body -fat soluble drugs remain longer in the body with prolonged effects – of importance for some sedatives and anxiolytics • Reduced kidney function - decreased excretion of some cardiovascular drugs, some antibiotics, diabetic drugs, antiinflammatory drugs – need t ...
07 Adrenoceptor-antagonist
... appropriate drug should be selected from those that have documented efficacy for the disease • For example in heart failure clinical trials have demonstrated that at least three antagonists— metoprolol, bisoprolol, and carvedilol—are effective in reducing mortality associated with chronic heart fail ...
... appropriate drug should be selected from those that have documented efficacy for the disease • For example in heart failure clinical trials have demonstrated that at least three antagonists— metoprolol, bisoprolol, and carvedilol—are effective in reducing mortality associated with chronic heart fail ...
Bronchitis and Pneumonia Drugs
... heart failure, asthma, bronchitis, or other chronic lung diseases. It should be used with caution in animals with severe heart disease, abnormal heart rhythms, kidney or liver impairment, or high blood pressure. Theophylline has been shown to cause stomach irritation and nervous system stimulation. ...
... heart failure, asthma, bronchitis, or other chronic lung diseases. It should be used with caution in animals with severe heart disease, abnormal heart rhythms, kidney or liver impairment, or high blood pressure. Theophylline has been shown to cause stomach irritation and nervous system stimulation. ...
Pharmacology Exam for Grade 2008 Pakistan Students
... E. CNS stimulation 18. About the action mechanisms of drugs, which one is true? A. Benzodiazepines increase the efficiency of GABAergic inhibition, mediating inhibitory synaptic response B. Selegiline is a Dopamine Receptor Agonists C. Barbiturates decrease the efficiency of GABAergic inhibition, me ...
... E. CNS stimulation 18. About the action mechanisms of drugs, which one is true? A. Benzodiazepines increase the efficiency of GABAergic inhibition, mediating inhibitory synaptic response B. Selegiline is a Dopamine Receptor Agonists C. Barbiturates decrease the efficiency of GABAergic inhibition, me ...
Chapter 7 - Westford Academy Forensics
... Schedule III—lower potential for abuse than the drugs in I or II; a currently accepted medical use in the US; abuse may lead to moderate physical dependence or high psychological dependence Schedule IV—low potential for abuse relative to drugs in III; a currently accepted medical use in the US; abus ...
... Schedule III—lower potential for abuse than the drugs in I or II; a currently accepted medical use in the US; abuse may lead to moderate physical dependence or high psychological dependence Schedule IV—low potential for abuse relative to drugs in III; a currently accepted medical use in the US; abus ...
Steve Brinksman - Addiction to medicines
... Tolerance to the different benzodiazepine effects such as anxiolytic, sedation and pleasure, develops at different speed, and this speed varies between individuals and can change in individuals over time. Tolerance can develop rapidly and increased doses are required to maintain the same effect, esp ...
... Tolerance to the different benzodiazepine effects such as anxiolytic, sedation and pleasure, develops at different speed, and this speed varies between individuals and can change in individuals over time. Tolerance can develop rapidly and increased doses are required to maintain the same effect, esp ...
What do you know about ECSTASY?
... • MDMA is a synthetic norepinephrine-related hallucinogenic drug • Not to be confused with “Herbal ecstasy” containing ephedrine and other herbs • Reputed to be a safe “recreational” or “therapeutic” drug in a dose of 1 to 2 mg. ...
... • MDMA is a synthetic norepinephrine-related hallucinogenic drug • Not to be confused with “Herbal ecstasy” containing ephedrine and other herbs • Reputed to be a safe “recreational” or “therapeutic” drug in a dose of 1 to 2 mg. ...
Antidepressiva werken niet
... They reviewed published clinical trial data, and unpublished data secured under Freedom of Information legislation. They focused on drugs which work by increasing levels of the mood controlling chemical serotonin in the brain. These included fluoxetine (Prozac) and paroxetine (Seroxat), from the cla ...
... They reviewed published clinical trial data, and unpublished data secured under Freedom of Information legislation. They focused on drugs which work by increasing levels of the mood controlling chemical serotonin in the brain. These included fluoxetine (Prozac) and paroxetine (Seroxat), from the cla ...
Types of abused prescription drugs
... achieve the same effect. The user, trying to reach the same high, may raise the dose to a level that results in coma or death by overdose. Long-term use of depressants can produce depression, chronic fatigue, breathing difficulties, sexual problems and sleep problems. As a dependency on the drug inc ...
... achieve the same effect. The user, trying to reach the same high, may raise the dose to a level that results in coma or death by overdose. Long-term use of depressants can produce depression, chronic fatigue, breathing difficulties, sexual problems and sleep problems. As a dependency on the drug inc ...
Basics of Drug Testing Many factors influence the length of time
... Many factors influence the length of time required for drugs to be metabolized and excreted through the urine. The most important of these is the half-life of the drug. Half-life refers to the amount of time the body requires to reduce the amount of a given drug to undetectable levels. The length of ...
... Many factors influence the length of time required for drugs to be metabolized and excreted through the urine. The most important of these is the half-life of the drug. Half-life refers to the amount of time the body requires to reduce the amount of a given drug to undetectable levels. The length of ...
Slide 1
... signaling properties of cortical pyramidal neurons and affect cognition and perception processes in the brain cortex. TINS, 2009. ...
... signaling properties of cortical pyramidal neurons and affect cognition and perception processes in the brain cortex. TINS, 2009. ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.