Drugs Safety in Pregnancy
... – Water soluble drugs are distributed and “diluted” more than in the nonpregnant state. – Drug dosage requirements may increase. – This effect may be offset by other pharmacokinetic changes of pregnancy. ...
... – Water soluble drugs are distributed and “diluted” more than in the nonpregnant state. – Drug dosage requirements may increase. – This effect may be offset by other pharmacokinetic changes of pregnancy. ...
CSB332H1
... Neurobiology is a sub discipline of biology & neuroscience, which is focused on the study of neurons at both the cellular and systems levels. A major focus in neurobiology research is the synapse, which is a specialized junction at which neurons communicate with one another, and with muscles and gla ...
... Neurobiology is a sub discipline of biology & neuroscience, which is focused on the study of neurons at both the cellular and systems levels. A major focus in neurobiology research is the synapse, which is a specialized junction at which neurons communicate with one another, and with muscles and gla ...
H2 receptor antagonist comparative dosing
... Action: H1: postsynaptic: excitatory vestibular: H2: postsynaptic: excitatory vestibular: H3: presynaptic: autoreceptor (reduces histamine) H4. The chemical bisphenol A (BPA) is produced in large quantities for the production of polycarbonate (PC) and epoxy resin plastics, which are used various dai ...
... Action: H1: postsynaptic: excitatory vestibular: H2: postsynaptic: excitatory vestibular: H3: presynaptic: autoreceptor (reduces histamine) H4. The chemical bisphenol A (BPA) is produced in large quantities for the production of polycarbonate (PC) and epoxy resin plastics, which are used various dai ...
UNIVERSITY OF SANTO TOMAS FACULTY OF MEDICINE AND
... and they remain receptive to ingested dopamine acting through the residual nigral neurons. Side effects: nausea, vomiting, anorexia, mild orthostatic hypotension, end-of-dose reduction in efficacy, involuntary dyskinetic movements: restlessness, head wagging, grimacing, lingual-labial dyskinesia, ch ...
... and they remain receptive to ingested dopamine acting through the residual nigral neurons. Side effects: nausea, vomiting, anorexia, mild orthostatic hypotension, end-of-dose reduction in efficacy, involuntary dyskinetic movements: restlessness, head wagging, grimacing, lingual-labial dyskinesia, ch ...
Soft Drug
... statistics, mathematics, chemistry, biochemistry, physics, and linguistics. • It has many practical applications in different areas of biology and medicine. ...
... statistics, mathematics, chemistry, biochemistry, physics, and linguistics. • It has many practical applications in different areas of biology and medicine. ...
Beating an addiction to meth
... Among the drugs being tested: calcium-channel blockers, a class of drugs used to treat high blood pressure that may inhibit the excessive release of neurotransmitters and reduce the “reward” of using methamphetamine; the anti-nausea drug Zofran, which has been shown to work against relapse in alcoho ...
... Among the drugs being tested: calcium-channel blockers, a class of drugs used to treat high blood pressure that may inhibit the excessive release of neurotransmitters and reduce the “reward” of using methamphetamine; the anti-nausea drug Zofran, which has been shown to work against relapse in alcoho ...
Do Illicit Street Drugs Cause Schizophrenia
... Several other studies in drug clinics show a similar increased incidence of multiple mutations. Drug users who have become psychotic and attend clinics are likely to have impaired drug metabolism. The likelihood of multiple CYP450 mutations makes CYP450 worth investigating in substance-induced co ...
... Several other studies in drug clinics show a similar increased incidence of multiple mutations. Drug users who have become psychotic and attend clinics are likely to have impaired drug metabolism. The likelihood of multiple CYP450 mutations makes CYP450 worth investigating in substance-induced co ...
Medications for the Treatment of Alcohol Dependence
... Medications for the Treatment of Alcohol Dependence REVIA (Naltrexone) ...
... Medications for the Treatment of Alcohol Dependence REVIA (Naltrexone) ...
First-pass effect
... • Noncompetitive antagonism exists when two drugs fit in the same receptor site but their intrinsic activities are not opposite of one another and the two drugs do not reverse each other. In this case one drug either combines better with the receptor or one drug alters the shape of the receptor when ...
... • Noncompetitive antagonism exists when two drugs fit in the same receptor site but their intrinsic activities are not opposite of one another and the two drugs do not reverse each other. In this case one drug either combines better with the receptor or one drug alters the shape of the receptor when ...
Is Nicotine a Gateway to Cocaine Addiction
... genetic mutations, which change DNA itself, epigenetic changes do not modify genes; instead, they influence the level of gene activity. In the brain such changes can affect learning and memory. These epigenetic shifts could help explain why nicotine enhances certain aspects of mental performance and ...
... genetic mutations, which change DNA itself, epigenetic changes do not modify genes; instead, they influence the level of gene activity. In the brain such changes can affect learning and memory. These epigenetic shifts could help explain why nicotine enhances certain aspects of mental performance and ...
Emergency Pharmacology
... Human studies Phase I - initial pharmacologic evaluation. Goal to prove drug’s safety and to identify tolerable dosages Phase II – limited controlled evaluation. Designed to test drug’s effect on the specific illness it was designed for. After completion of this phase, a new drug application c ...
... Human studies Phase I - initial pharmacologic evaluation. Goal to prove drug’s safety and to identify tolerable dosages Phase II – limited controlled evaluation. Designed to test drug’s effect on the specific illness it was designed for. After completion of this phase, a new drug application c ...
It`s a Brain Disease: Beyond a Reasonable Doubt
... Co-morbid mental illness Early physical or sexual abuse Witnessing violence Stress Peers who use drugs Drug availability ...
... Co-morbid mental illness Early physical or sexual abuse Witnessing violence Stress Peers who use drugs Drug availability ...
Variation in Drug Responsiveness
... 1. drug’s mode of interactions with receptors (see partial agonists) 2. characteristics of the receptor-effector system involved (eg, diuretics that act on one portion of nephron may produce much greater excretion of sodium than diuretics that act elsewhere) 3. efficacy is limited by the drug’s abil ...
... 1. drug’s mode of interactions with receptors (see partial agonists) 2. characteristics of the receptor-effector system involved (eg, diuretics that act on one portion of nephron may produce much greater excretion of sodium than diuretics that act elsewhere) 3. efficacy is limited by the drug’s abil ...
Can psychedelic drugs play a role in palliative care?
... scene. Like LSD, MDMA began its life in medicine, when used in the early 1980s as a drug to enhance the psychotherapeutic process. MDMA promotes relaxation, loosens the ego and encourages increased contemplativeness.3 These effects can produce a state of improved insight and aid a greater exploratio ...
... scene. Like LSD, MDMA began its life in medicine, when used in the early 1980s as a drug to enhance the psychotherapeutic process. MDMA promotes relaxation, loosens the ego and encourages increased contemplativeness.3 These effects can produce a state of improved insight and aid a greater exploratio ...
Зразок для теоретичних кафедр
... action, the degree of liver metabolism. Among the first three generations of H2histamine receptors blockers cimetidine least hydrophilic, resulting in a short halflife and considerable metabolism in the liver. Thanks to the latter it interacts with the microsomal enzyme - cytochrome P450, altering t ...
... action, the degree of liver metabolism. Among the first three generations of H2histamine receptors blockers cimetidine least hydrophilic, resulting in a short halflife and considerable metabolism in the liver. Thanks to the latter it interacts with the microsomal enzyme - cytochrome P450, altering t ...
Dexedrine Tablets
... carefully monitored in children as growth retardation may occur. Children who are not gaining weight as expected should have their treatment interrupted temporarily. Caution should be used when administering dexamfetamine to patients with impaired kidney function or unstable personality. Drug depend ...
... carefully monitored in children as growth retardation may occur. Children who are not gaining weight as expected should have their treatment interrupted temporarily. Caution should be used when administering dexamfetamine to patients with impaired kidney function or unstable personality. Drug depend ...
Table of Antidotes (Word Document, 20kB)
... formation of methemoglobin, which combines with cyanide to form nontoxic cyanmethemoglobin. ...
... formation of methemoglobin, which combines with cyanide to form nontoxic cyanmethemoglobin. ...
EUPPI for RPD
... and Serotonin Syndrome: There have been reports describing patients with symptoms compatible with serotonin syndrome (including altered mental status, autonomic instability and neuromuscular abnormalities) following the use of selective serotonin reuptake inhibitors (SSRIs) or serotonin noradrenalin ...
... and Serotonin Syndrome: There have been reports describing patients with symptoms compatible with serotonin syndrome (including altered mental status, autonomic instability and neuromuscular abnormalities) following the use of selective serotonin reuptake inhibitors (SSRIs) or serotonin noradrenalin ...
and drug
... Theoretically, the amount of randomly selected drugs having bioavailability in the CNS is less than 2% of small molecules and practically 0% of large molecules. These numbers are also reflected by the drugs currently available for CNS diseases. Of over 7,000 potential drugs in the comprehensive medi ...
... Theoretically, the amount of randomly selected drugs having bioavailability in the CNS is less than 2% of small molecules and practically 0% of large molecules. These numbers are also reflected by the drugs currently available for CNS diseases. Of over 7,000 potential drugs in the comprehensive medi ...
Opioids OD fact sheet
... Dextropropoxyphene: significant Na channel blocking effect ( long QRS, HB, arrhythmia), seizures if >1g, may require larger doses of naloxone, can cause death in <1hr Tramadol: µ-receptor and M1 action; inhibits reuptake of 5-HT and NAD, stimulate 5-HT release; toxic dose > 1.5g (>10mg/kg); 70-90% ...
... Dextropropoxyphene: significant Na channel blocking effect ( long QRS, HB, arrhythmia), seizures if >1g, may require larger doses of naloxone, can cause death in <1hr Tramadol: µ-receptor and M1 action; inhibits reuptake of 5-HT and NAD, stimulate 5-HT release; toxic dose > 1.5g (>10mg/kg); 70-90% ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.