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Principles of prescribing • Non-specialists do not usually have
Principles of prescribing • Non-specialists do not usually have

... Selegiline Selegiline can be useful at the onset of motor fluctuations as an alternative to dopamine agonists or COMT inhibition. It can be used as monotherapy but the evidence for any neuroprotective effect in early disease is not established.2 ...
GI system - WEB БАЗИРАНО ОБУЧЕНИЕ ПО
GI system - WEB БАЗИРАНО ОБУЧЕНИЕ ПО

... it also blocks 5-HT3-receptors. It crosses BBB. Its prokinetic action (stimulation of GI motility) is connected with stimulation of 5-HT4-receptors, present on excitatory interneurons, which enhances ACh release from primary cholinergic neurons in myenteric plexus. Metoclopramide is used as antiemet ...
Click here for handout
Click here for handout

Neuroprotective effects of some newer and potential antiepileptic
Neuroprotective effects of some newer and potential antiepileptic

... Other neurological conditions are also associated with neurodegeneration, for example, stroke, head injury and chronic neurodegenerative diseases. In this review, the neuroprotective effects of a number of newer or potential antiepileptic drugs (AEDs) are considered in general in models of experimen ...
E: Psychoactive Drugs Other than Narcotics and Stimulants
E: Psychoactive Drugs Other than Narcotics and Stimulants

False Positive Urine Screens for Phencyclidine
False Positive Urine Screens for Phencyclidine

... False Positive Urine Screens for Phencyclidine Antibody-based enzyme-mediated immunoassays are used in the emergency department for screening of the urine for substances of abuse. These immunoassays have become the prevailing technology despite limitations such as the weak specificity for phencyclid ...
April 2009, Number 04
April 2009, Number 04

... opioid with compli­cated pharmacokinetic properties and pharmacodynamic effects that make it difficult to use. Since methadone is a “longacting” opioid, it can be used for the treatment of pain, which is regulated like all other Schedule II controlled substances. Methadone has a black box warning in ...
Drugs for Bacterial Infections
Drugs for Bacterial Infections

... ACTION: Prevent the enzyme cholinesterase (CHE) from inactivating acetycholine (ACh), thereby increasing the amount of ACh available at receptor sites. Transmission of nerve impulses is increased at all sites responding to ACh as a transmitter Therapeutic Use (TU) increases muscle strength by increa ...
Legal Highs: Harms and Effects
Legal Highs: Harms and Effects

... impact on your short term memory so can be very disruptive to your study, work and can increase heart rate and blood pressure. They are powerful dissociative drugs and can give very disturbing and prolonged experience particularly for less experienced drug takers. There may be a high risk of physica ...
How to Dispose of Unused Medicines I
How to Dispose of Unused Medicines I

... manufacturer, has determined this method to be the most appropriate route of disposal that presents the least risk to safety. About a dozen drugs, such as powerful narcotic pain relievers and other controlled substances, carry instructions for flushing to reduce the danger of unintentional use or ov ...
antimycobacterials
antimycobacterials

... Isoniazid may increase levels of phenytoin, carbamazepine, diazepam, ethosuximide, primidone, theophylline, and warfarin. ...
What`s Cannabis Got To Do With It
What`s Cannabis Got To Do With It

... are no more common now than they were in times when pot was uncommon, so it is not likely that cannabis causes these illnesses. However, if you have emotional or psychological problems, you should know that people who use cannabis have more episodes of their illness and relapse more often. They gene ...
Spring 2015-Chapter 24
Spring 2015-Chapter 24

... linked to diseases ranging from irritable bowel syndrome and cardiovascular disease, to osteoporosis. Now, researchers from the California Institute of Technology (Caltech) in Pasadena report a study in the journal Cell that shows certain bacteria in the gut play an important role in the production ...
7 Intro to Antibiotic Therapy- A
7 Intro to Antibiotic Therapy- A

... The rise of the resistance movement Indiscriminate use of antimicrobial drugs has serious consequences. Unnecessary exposure of organisms to these drugs encourages the emergence of resistant strains, which are likely to do far more damage than their predecessors. ...
Premedication mgmc
Premedication mgmc

... parental presence on induction of anesthesia an increase in heart rate and skin conductance levels in mothers Oral midaz better than parent and the combined is not very superior IV midaz – wait for 4.8 minutes Intranasal – 10 minutes ...
Targeting the dopamine D receptor in schizophrenia
Targeting the dopamine D receptor in schizophrenia

... relation to their clinical antipsychotic potencies, as illustrated in Figure 2. No other receptor, including any other dopamine receptor, or any of the serotonin receptors or glutamate receptors, exhibit such a correlation. Although this well-established finding in Figure 2 may be criticised as simp ...
Drug dosing in HD-Almadinah-2014
Drug dosing in HD-Almadinah-2014

... • drugs with larger MW removed by HD take longer to equilibrate from intra/extracellular compartments and may result in post-dialysis rebound Protein binding of drug – high protein bound = less clearance ...
orciprenaline condensed - EBL
orciprenaline condensed - EBL

... •It is marketed by GlaxoSmithKline as Ventolin, Aerolin or Ventorlin. •Salbutamol was the first selective Β2-receptor agonist to be marketed — in 1968. It was first sold by Allen & Hanburys under the brand name Ventolin. •Salbutamol is specifically indicated by Acute asthma. •The most common side ef ...
Microbiology
Microbiology

Posttraumatic Stress Disorder and Military Veterans
Posttraumatic Stress Disorder and Military Veterans

... It’s based on Social Cognitive Theory that focuses on how the traumatic event is construed and coped with by the client who is trying to regain a sense of mastery and control in their life. The theory behind CPT conceptualizes PTSD as a disorder of "non-recovery" in which erroneous beliefs about the ...
Slide () - Access Emergency Medicine
Slide () - Access Emergency Medicine

... CYP2C9 and CYP1A9 to primary metabolites that retain affinity and ability to bind with cannabinoid receptors. One JWH-018 primary metabolite, acts as a antagonist at CB1. Secondary metabolites are formed by conjugation. These metabolites may retain ability to bind to cannabinoid receptors but at thi ...
NIDA InfoFacts- Steroids (Anabolic-Androgenic)
NIDA InfoFacts- Steroids (Anabolic-Androgenic)

... Animal studies have shown that AAS are reinforcing—that is, animals will self-administer AAS when given the opportunity, just as they do with other addictive drugs. 3,4 This property is more difficult to demonstrate in humans, but the potential for AAS abusers to become addicted is consistent with t ...
ALLEGRON
ALLEGRON

... debrisoquin, dextromethorphan and the tricyclic antidepressants. These individuals may have higher than expected plasma concentrations of tricyclic antidepressants when given usual doses. In addition, certain drugs that are metabolised by this isoenzyme, including many antidepressants (tricyclic ant ...
Antimalarial Drugs
Antimalarial Drugs

... Acts by inhibiting the Dihyrofolate Reductase enzyme Used with combination atavaquone (primarily) for o Multi-drug resistance falciparum malaria Very safe CLASS 2 ANTIMALARIAL DRUGS ...
Oxycodone - getuponit.ca
Oxycodone - getuponit.ca

... Oxycodone is in a group of drugs known as opioids or narcotic analgesic pain relievers. It is a drug available in liquid, tablet and capsule form used to medically relieve moderate to severe short term and long term pain. It reduces pain by working on the central nervous system and changing the way ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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