The treatment of hypertension IN THE ELDERLY
... a. True. Particularly in case of older well-hydrated patients, therapy with thiazides may result in serious hyponatremia (together with hypokalemia) even with short-term therapy. These diuretics are actively secreted in the proximal tubules and block reabsorption of Na+ and Cl- in the early distal c ...
... a. True. Particularly in case of older well-hydrated patients, therapy with thiazides may result in serious hyponatremia (together with hypokalemia) even with short-term therapy. These diuretics are actively secreted in the proximal tubules and block reabsorption of Na+ and Cl- in the early distal c ...
Revealing the paradox of drug reward in human evolution
... array of chemical defences to deter heterotrophic predators (insect and vertebrate herbivores, fungi and microbes; Wink 1998). All cellular organisms possess internal signalling systems to regulate metabolism, growth and reproduction, which depend on small quantities of simple molecules such as amin ...
... array of chemical defences to deter heterotrophic predators (insect and vertebrate herbivores, fungi and microbes; Wink 1998). All cellular organisms possess internal signalling systems to regulate metabolism, growth and reproduction, which depend on small quantities of simple molecules such as amin ...
February 2008, Number 2
... Ropinirole was reviewed for possible addition in the Formulary due to its relatively high nonformulary use at Shands at UF. Ropinirole is an oral non-ergot alkaloid dopamine agonist with FDA labeled indications for both Parkinson’s disease (PD) and Restless Leg Syndrome (RLS). Ropinirole is an agoni ...
... Ropinirole was reviewed for possible addition in the Formulary due to its relatively high nonformulary use at Shands at UF. Ropinirole is an oral non-ergot alkaloid dopamine agonist with FDA labeled indications for both Parkinson’s disease (PD) and Restless Leg Syndrome (RLS). Ropinirole is an agoni ...
PowerPoint-Präsentation
... Anxiolytic substances occupy a prominent post in the ranking of the most utilized drugs by man. However, the anxiolytic drugs have an unfavorable risk/benefit ratio, especially benzodiazepines. Several medicinal plants have been used in traditional folk medicine for their anxiolytic or sedative prop ...
... Anxiolytic substances occupy a prominent post in the ranking of the most utilized drugs by man. However, the anxiolytic drugs have an unfavorable risk/benefit ratio, especially benzodiazepines. Several medicinal plants have been used in traditional folk medicine for their anxiolytic or sedative prop ...
Me-too drugs: is there a problem
... for most patients, while others are better for a substantial fraction of patients. The increased choice between drugs can be very valuable, particularly for patients for whom the pioneer drug is ineffective or entails undesirable side effects.2 In addition, for some classes of drugs, such as antibio ...
... for most patients, while others are better for a substantial fraction of patients. The increased choice between drugs can be very valuable, particularly for patients for whom the pioneer drug is ineffective or entails undesirable side effects.2 In addition, for some classes of drugs, such as antibio ...
Antiviral for respiratory viral infection
... 6. Protease inhibitors: a protease cuts viral protein chains apart so they can be assembled into their final configuration. 7. Assembly inhibitors: Rifampicin acts at the assembly phase. 8. Release inhibitors: The final stage in the life cycle of a virus is the release of completed viruses from the ...
... 6. Protease inhibitors: a protease cuts viral protein chains apart so they can be assembled into their final configuration. 7. Assembly inhibitors: Rifampicin acts at the assembly phase. 8. Release inhibitors: The final stage in the life cycle of a virus is the release of completed viruses from the ...
Use of ophthalmic medications during pregnancy
... aqueous humour and hence decrease the intra-ocular pressure. A review suggested that β-adrenergic tone affects the foetal heart rate and that β-blockers are potentially harmful to the developing foetus.32 In 1979, the use of timolol and its association with an episode of apnoea in an 18-month-old ch ...
... aqueous humour and hence decrease the intra-ocular pressure. A review suggested that β-adrenergic tone affects the foetal heart rate and that β-blockers are potentially harmful to the developing foetus.32 In 1979, the use of timolol and its association with an episode of apnoea in an 18-month-old ch ...
Muscarinic antagonist
... pupils, photophobia, dry mouth and potentially extreme confusion, dissociative hallucinations and excitation especially amongst the elderly. These latter effects are because atropine is able to cross the blood-brain barrier. Because of the hallucinogenic properties, some have used the drug recreatio ...
... pupils, photophobia, dry mouth and potentially extreme confusion, dissociative hallucinations and excitation especially amongst the elderly. These latter effects are because atropine is able to cross the blood-brain barrier. Because of the hallucinogenic properties, some have used the drug recreatio ...
DRUGS INFLUENCING COGNITIVE FUNCTION
... the treatment of geriatric disorders like Alzheimer's which have become one of the major problems socially and medically. Considerable evidence has been gathered in the last decade to support the observation that children with epilepsy have more learning difficulties than age matched controls (2, 3) ...
... the treatment of geriatric disorders like Alzheimer's which have become one of the major problems socially and medically. Considerable evidence has been gathered in the last decade to support the observation that children with epilepsy have more learning difficulties than age matched controls (2, 3) ...
Atropine
... pupils, photophobia, dry mouth and potentially extreme confusion, dissociative hallucinations and excitation especially amongst the elderly. These latter effects are because atropine is able to cross the blood-brain barrier. Because of the hallucinogenic properties, some have used the drug recreatio ...
... pupils, photophobia, dry mouth and potentially extreme confusion, dissociative hallucinations and excitation especially amongst the elderly. These latter effects are because atropine is able to cross the blood-brain barrier. Because of the hallucinogenic properties, some have used the drug recreatio ...
2007 Guidelines for the Management of Arterial Hypertension
... Antihypertensive treatment is beneficial in hypertensive patients as well as in subjects with BP in the high normal range. So, BP goal should be <130/80 ...
... Antihypertensive treatment is beneficial in hypertensive patients as well as in subjects with BP in the high normal range. So, BP goal should be <130/80 ...
NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS) AND
... These drugs can reduce pain, stiffness, movement limitations or swelling associated with either soft tissue injuries or rheumatic dysfunction. However, conclusive evidence on the role of these drugs as adjuvants to physiotherapy needs to be established. Because all NSAIDs are not equipotent and ther ...
... These drugs can reduce pain, stiffness, movement limitations or swelling associated with either soft tissue injuries or rheumatic dysfunction. However, conclusive evidence on the role of these drugs as adjuvants to physiotherapy needs to be established. Because all NSAIDs are not equipotent and ther ...
Treatment of Headaches During Pregnancy and Lactation g y
... – Lipophilicity – Protein binding – Ionisation (e.g. pKa of a drug and “milk‐trapping”) ...
... – Lipophilicity – Protein binding – Ionisation (e.g. pKa of a drug and “milk‐trapping”) ...
File - Riske Science
... well as possible side-effects and potential problems of tolerance and addiction. • Determining appropriate dosage is usually quite dif cult as there are so many variables involved – for example the age, sex, and weight of the patient, as well as factors such as diet and environment. Interactions wit ...
... well as possible side-effects and potential problems of tolerance and addiction. • Determining appropriate dosage is usually quite dif cult as there are so many variables involved – for example the age, sex, and weight of the patient, as well as factors such as diet and environment. Interactions wit ...
cat june2006 fri finley - California Association of Toxicologists
... Artifact (ie - preliminary data only) Depressed children/adolescents are more impulsive Children are receiving proportionately higher doses Antidepressants have different PK/PD properties in children Greater influence/activity of 5HT system in children ...
... Artifact (ie - preliminary data only) Depressed children/adolescents are more impulsive Children are receiving proportionately higher doses Antidepressants have different PK/PD properties in children Greater influence/activity of 5HT system in children ...
RAYMOND GEORGE RESEARCH SYNOPSIS
... The laboratory is on track to an Investigational New Drug (IND) Application regarding novel drug(s) that target brain serotonin receptors for treatment of neuropsychiatric disorders, including, autism spectrum disorder, obsessive-compulsive disorders (binge eating, attention deficit-hyperactivity di ...
... The laboratory is on track to an Investigational New Drug (IND) Application regarding novel drug(s) that target brain serotonin receptors for treatment of neuropsychiatric disorders, including, autism spectrum disorder, obsessive-compulsive disorders (binge eating, attention deficit-hyperactivity di ...
Cimetidine - Doctors Foster and Smith
... Cimetidine is in a class of drugs called H2 receptor antagonists. It is used to decrease the amount of stomach acid produced. This aids in the treatment of ulcers that are present and helps prevent ulcer formation. It is also used in the treatment of gastritis (inflammation of the stomach), esophagi ...
... Cimetidine is in a class of drugs called H2 receptor antagonists. It is used to decrease the amount of stomach acid produced. This aids in the treatment of ulcers that are present and helps prevent ulcer formation. It is also used in the treatment of gastritis (inflammation of the stomach), esophagi ...
Therapy of peptic ulcer
... The oral dose in peptic ulcer is 300 mg for 4-8 weeks, then, 150 mg daily for 6 months or more as maintenance dose. )Ranitidine doesn’t significantly affect the cytochrome oxidase P-450, thus the subsequent drug interactions are not reported. The risk of untoward antiandrogenic effects and hyperprol ...
... The oral dose in peptic ulcer is 300 mg for 4-8 weeks, then, 150 mg daily for 6 months or more as maintenance dose. )Ranitidine doesn’t significantly affect the cytochrome oxidase P-450, thus the subsequent drug interactions are not reported. The risk of untoward antiandrogenic effects and hyperprol ...
Muscle Relaxers
... Spasmolytics are referred to as “centrally acting muscle relaxants” because they can be used to target specific regions of the body such as low back and neck. ...
... Spasmolytics are referred to as “centrally acting muscle relaxants” because they can be used to target specific regions of the body such as low back and neck. ...
often marketed as " incense." Citing an imminent
... material in granular, loose leaf or powder form, or in liquid or as a food additive, or any herbal- incense -type stimulant or hallucinogen product, when the label is in any way false ...
... material in granular, loose leaf or powder form, or in liquid or as a food additive, or any herbal- incense -type stimulant or hallucinogen product, when the label is in any way false ...
Dermatologic Pharmacology
... sunscreen is a measure of its effectiveness in absorbing erythrogenic ultraviolet light. It is determined by measuring the minimal erythema (abnormal redness of the skin) dose with and without the sunscreen in a group of normal people. The ratio of the minimal erythema dose with sunscreen to the min ...
... sunscreen is a measure of its effectiveness in absorbing erythrogenic ultraviolet light. It is determined by measuring the minimal erythema (abnormal redness of the skin) dose with and without the sunscreen in a group of normal people. The ratio of the minimal erythema dose with sunscreen to the min ...
70-ORGANIC PHARMACEUTICAL CHEMISTRY III
... Aims are the critical knowledge and thorough examination of synthesis, structure, correlation of structure with drug action, fate of the drugs in the organism, sites of loss, therefore duration of drug action. Aim is also to familiarise the students with relations governing molecules acting on CNS a ...
... Aims are the critical knowledge and thorough examination of synthesis, structure, correlation of structure with drug action, fate of the drugs in the organism, sites of loss, therefore duration of drug action. Aim is also to familiarise the students with relations governing molecules acting on CNS a ...
this PDF file - Journal of the Indian Institute of Science
... I is assunlcd that there :ire three kinds of inleraction between an opiate and membranes containing opiate receptorsL1: (1) A non-specific saturable binding consisting primarily of interactions between thc protonated nitrogen atom of Lhe opiate and anionic group:, of monbrntlc niacromolecules. (2) A ...
... I is assunlcd that there :ire three kinds of inleraction between an opiate and membranes containing opiate receptorsL1: (1) A non-specific saturable binding consisting primarily of interactions between thc protonated nitrogen atom of Lhe opiate and anionic group:, of monbrntlc niacromolecules. (2) A ...
THE SAFE HANDLING, COLLECTION AND DISPOSAL OF DRUGS
... Children must be informed what procedure to follow. A child must not touch the substance but inform a member of staff immediately. ...
... Children must be informed what procedure to follow. A child must not touch the substance but inform a member of staff immediately. ...
Sleep Pharmacology
... with priapism as a rare side effect Fluoxetin causes “Prozac eyes in nonnon-REM sleep Mirtazepine is a H1 receptor antagonist with sedating properties ...
... with priapism as a rare side effect Fluoxetin causes “Prozac eyes in nonnon-REM sleep Mirtazepine is a H1 receptor antagonist with sedating properties ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.