like palatable food con
... Current treatments for obesity and eating disorders lack sufficient efficacy and are complicated by high relapse rates and a wide range of side effects, thus highlighting the need to identify novel pharmacological targets that could lead to the development of more effective and safer therapies. Rese ...
... Current treatments for obesity and eating disorders lack sufficient efficacy and are complicated by high relapse rates and a wide range of side effects, thus highlighting the need to identify novel pharmacological targets that could lead to the development of more effective and safer therapies. Rese ...
Investigational Drugs
... Role of the Pharmacist in Investigational Drug Process • Serving on the Institutional Review Board (IRB)- sets up guidelines, reviews financial evaluations, review of proposal to investigate • Disseminating communication (preparation of DDS (drug data sheets), protocols for IDP • Accountability rec ...
... Role of the Pharmacist in Investigational Drug Process • Serving on the Institutional Review Board (IRB)- sets up guidelines, reviews financial evaluations, review of proposal to investigate • Disseminating communication (preparation of DDS (drug data sheets), protocols for IDP • Accountability rec ...
Medical Marijuana Pros and Cons - Colorado Behavioral Healthcare
... Will need to get a thorough history - medically, psychiatrically and substance abuse – keep a chart and have a patient/physician relationship Will need to attempt to decide what level of marijuana use is most appropriate Will need to recommend patients not drive etc. when under the influence Will ne ...
... Will need to get a thorough history - medically, psychiatrically and substance abuse – keep a chart and have a patient/physician relationship Will need to attempt to decide what level of marijuana use is most appropriate Will need to recommend patients not drive etc. when under the influence Will ne ...
Hydroxyzine-Induced Dystonia
... Dystonia is abnormal, involuntary muscle movements due to sustained muscle contractions resulting in twisting and/or repetitive, patterned movements. In children, dystonia is more commonly secondary and thus usually represents a symptom caused by an underlying brain disorders. Triggers include infec ...
... Dystonia is abnormal, involuntary muscle movements due to sustained muscle contractions resulting in twisting and/or repetitive, patterned movements. In children, dystonia is more commonly secondary and thus usually represents a symptom caused by an underlying brain disorders. Triggers include infec ...
Adulterated and misbranded drugs
... ii. an accurate statement of the quantity of the contents in terms of weight, measure, or numerical count. 3. If it does not contain any statement, word or other information required by or under authority of this Act to appear on the label so as to render it likely to be read and understood by the o ...
... ii. an accurate statement of the quantity of the contents in terms of weight, measure, or numerical count. 3. If it does not contain any statement, word or other information required by or under authority of this Act to appear on the label so as to render it likely to be read and understood by the o ...
pethidine
... People with decreased production of natural steroid hormones by the adrenal glands. Addison's disease Tumor of the adrenal gland ...
... People with decreased production of natural steroid hormones by the adrenal glands. Addison's disease Tumor of the adrenal gland ...
Session 1 Anxiety disorders
... Generalised anxiety disorder Acute anxiety attacks (Panic episodes) Substance-induced panic episodes Panic disorder ...
... Generalised anxiety disorder Acute anxiety attacks (Panic episodes) Substance-induced panic episodes Panic disorder ...
Treatment issues for psychiatric comorbidities of epilepsy
... Two main issues are relevant when using antidepressant drugs in patients with epilepsy, namely pharmacological interactions (both pharmacodynamics and pharmacokinetics) and the potential impact on seizure threshold [21] . In general terms, new antidepressants, such as selective serotonin reuptake in ...
... Two main issues are relevant when using antidepressant drugs in patients with epilepsy, namely pharmacological interactions (both pharmacodynamics and pharmacokinetics) and the potential impact on seizure threshold [21] . In general terms, new antidepressants, such as selective serotonin reuptake in ...
Opioids and Sucrose: An Overview
... derived from the poppy seed Papaver somniferum. First reference to the substance dates back to 300B.C. ► An important active principle in opium was isolated in 19th century and named morphine (after Morpheus, Greek god of dreams). ► Attempts to separate analgesic properties of these compounds from t ...
... derived from the poppy seed Papaver somniferum. First reference to the substance dates back to 300B.C. ► An important active principle in opium was isolated in 19th century and named morphine (after Morpheus, Greek god of dreams). ► Attempts to separate analgesic properties of these compounds from t ...
AEDs - BC Epilepsy Society
... – Increases frequency at which GABA opens Clchannels (different site than benzodiazepines) – Antagonizes glutamate action at AMPA/kainate receptor subtype – Inhibition of carbonic anydrase ...
... – Increases frequency at which GABA opens Clchannels (different site than benzodiazepines) – Antagonizes glutamate action at AMPA/kainate receptor subtype – Inhibition of carbonic anydrase ...
Local Anesthetics
... LA: Reversibly block impulse conduction along nerve axons & other excitable membrane that utilize Na+ channels for Action Potential generation. Uses: block pain sensation (nociception) from specific area of ! body. Cocaine was ! 1st LA isolated from Coca plant as an ophthalmic anesthetic; Its chroni ...
... LA: Reversibly block impulse conduction along nerve axons & other excitable membrane that utilize Na+ channels for Action Potential generation. Uses: block pain sensation (nociception) from specific area of ! body. Cocaine was ! 1st LA isolated from Coca plant as an ophthalmic anesthetic; Its chroni ...
Tough Anesthesia Cases - VCA Specialty Animal Hospitals
... Higher risk patients = more potential for anesthetic complications If a patient was stable under anesthesia + this acutely changes = check the patient + check the machine! Pre‐op workup, vigilant monitoring + post‐op care is critical Pre‐oxygenate + minimize stress Drug choice, drug administrati ...
... Higher risk patients = more potential for anesthetic complications If a patient was stable under anesthesia + this acutely changes = check the patient + check the machine! Pre‐op workup, vigilant monitoring + post‐op care is critical Pre‐oxygenate + minimize stress Drug choice, drug administrati ...
Chapter 11
... Most widely consumed drug in the United States Such drugs increase alertness and increase energy Examples include amphetamines, cocaine, nicotine, and caffeine ...
... Most widely consumed drug in the United States Such drugs increase alertness and increase energy Examples include amphetamines, cocaine, nicotine, and caffeine ...
Patient Education DIAZEPAM
... IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your hea ...
... IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your hea ...
Caffeinism
... Half-life is reduced by 30–50 percent in smokers; doubled in women on oral contraceptives (and prolonged during last trimester of pregnancy). ...
... Half-life is reduced by 30–50 percent in smokers; doubled in women on oral contraceptives (and prolonged during last trimester of pregnancy). ...
trauma & pain relief
... In every trauma patient, main symptom will be pain. It is important to alleviate the pain so as the management of trauma becomes easy and make the patient comfortable. Inadequate control of pain will lead to more suffering of the patient and increase of hospital stay. ...
... In every trauma patient, main symptom will be pain. It is important to alleviate the pain so as the management of trauma becomes easy and make the patient comfortable. Inadequate control of pain will lead to more suffering of the patient and increase of hospital stay. ...
Drug Metabolism
... o Induction of CYP1A: exposure to polycyclic aromatic hydrocarbons from industrial pollutants, cigarette smoke, and charbroiled meats (induction both in liver and extrahepatically) o Induction of CYP3A4: glucocorticoids, anticonvulsants o Induction of CYP2E1: isoniazid, acetone, chronic EtOH consump ...
... o Induction of CYP1A: exposure to polycyclic aromatic hydrocarbons from industrial pollutants, cigarette smoke, and charbroiled meats (induction both in liver and extrahepatically) o Induction of CYP3A4: glucocorticoids, anticonvulsants o Induction of CYP2E1: isoniazid, acetone, chronic EtOH consump ...
Disinfectant
... 1. Give an antimicrobial drug only when it is indicated by rational choices 2. Give a sufficiently large amount of an effective drug as early as possible 3. Continue treatment long enough to ensure eradication of infection ...
... 1. Give an antimicrobial drug only when it is indicated by rational choices 2. Give a sufficiently large amount of an effective drug as early as possible 3. Continue treatment long enough to ensure eradication of infection ...
Chronic Microglial Activation and Excitotoxicity Secondary to
... is particularly important when considering that the persistence of measles virus in the brain is known to occur in 20 percent of the cases of exposure to the virus. This is much higher than is clinically evident. It is not even necessary that the virus enter the neurons, as with HIV-1 dementia. In t ...
... is particularly important when considering that the persistence of measles virus in the brain is known to occur in 20 percent of the cases of exposure to the virus. This is much higher than is clinically evident. It is not even necessary that the virus enter the neurons, as with HIV-1 dementia. In t ...
Extrapolating from animal studies to the efficacy in humans of a
... data to the expected effects in humans has been one of the basic problems in pharmacological and toxicological studies for many years (e.g. see Rall 1969; Levy 1987), and is especially critical in OP poisoning studies (e.g. see Burton 2003). Various species may differ in both the affinity and distri ...
... data to the expected effects in humans has been one of the basic problems in pharmacological and toxicological studies for many years (e.g. see Rall 1969; Levy 1987), and is especially critical in OP poisoning studies (e.g. see Burton 2003). Various species may differ in both the affinity and distri ...
... need in the study of drug action on aggression. The ethological approach has produced biologically valid test situations and detailed behavioral measurements in an effort to gain insight into causative and functional determinants of aggressive, defensive, submissive, and flight behaviors (25). This ...
Metabolism Phase-I
... 3. Some drugs can be partially eliminated from the body without any metabolism. Why? 4. Drug interacts with metabolizing enzyme in a manner similar to drug-target interaction. However, the later interaction leads to no products. Is it the similarity of drug to enzyme substrate will determine whether ...
... 3. Some drugs can be partially eliminated from the body without any metabolism. Why? 4. Drug interacts with metabolizing enzyme in a manner similar to drug-target interaction. However, the later interaction leads to no products. Is it the similarity of drug to enzyme substrate will determine whether ...
Anticholinergics for Overactive Bladder Therapy: Central Nervous
... The adverse events most commonly associated with the use of antimuscarinic OAB drugs are the expected side effects of anticholinergics, such as dry mouth and constipation. CNS adverse events were generally observed in fewer than 10% of patients in phase III clinical trials, and were highest in patie ...
... The adverse events most commonly associated with the use of antimuscarinic OAB drugs are the expected side effects of anticholinergics, such as dry mouth and constipation. CNS adverse events were generally observed in fewer than 10% of patients in phase III clinical trials, and were highest in patie ...
Chapter 16 Cholinesterase Inhibitors
... May occur with diarrhea, constipation, or both Considered IBS when symptoms have been present for 12 weeks over the past year ...
... May occur with diarrhea, constipation, or both Considered IBS when symptoms have been present for 12 weeks over the past year ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.