Biomedical aspects of chiral molecules
... A large proportion of pharmacologically active compounds possesses a chiral centre and therefore exists in at least two stereoisomeric forms. Because the human body is essentially a chiral structure incorporating many chiral drug targets, such as enzymes, receptors and ion channels the effect is tha ...
... A large proportion of pharmacologically active compounds possesses a chiral centre and therefore exists in at least two stereoisomeric forms. Because the human body is essentially a chiral structure incorporating many chiral drug targets, such as enzymes, receptors and ion channels the effect is tha ...
Post Operative Nausea & Vomiting
... (Substance P Receptors) Work on the final common pathway from the emetic center ...
... (Substance P Receptors) Work on the final common pathway from the emetic center ...
Back_to_basics_pharmacology 1, 2, 3 and 4 Dr Riachi 2012
... Meperidine: – 10 times less potent than morphine with shorter duration of action – Should only be used for acute pain – Contraindicated for treatment of chronic pain – Risk of accumulation of toxic metabolite normeperidine which could lead to anxiety, tremors, myoclonus, seizures with repeated doses ...
... Meperidine: – 10 times less potent than morphine with shorter duration of action – Should only be used for acute pain – Contraindicated for treatment of chronic pain – Risk of accumulation of toxic metabolite normeperidine which could lead to anxiety, tremors, myoclonus, seizures with repeated doses ...
Clinical Treatments
... o Pregnancy/pregnancy potential o Some drug-specific concerns o Adherence issues NNRTI Based Regimens: ...
... o Pregnancy/pregnancy potential o Some drug-specific concerns o Adherence issues NNRTI Based Regimens: ...
Essentials of ADHD Medications: From Mechanisms of Action to
... monoamine transporter (VMAT). After being taken up into the DA terminal via DAT (2), amphetamine is packaged into vesicles (3). At high levels, it will displace DA from the vesicles into the terminal (4), which will lead to DA being expelled from the terminal via two mechanisms: the opening of chann ...
... monoamine transporter (VMAT). After being taken up into the DA terminal via DAT (2), amphetamine is packaged into vesicles (3). At high levels, it will displace DA from the vesicles into the terminal (4), which will lead to DA being expelled from the terminal via two mechanisms: the opening of chann ...
Phosphodiesterase as drug targets in kinetoplastid parasites
... • Many different types and families, most important function is to catalyze reaction from cAMP to 5‘-AMP – Antagonist of Adenylylcyclases ...
... • Many different types and families, most important function is to catalyze reaction from cAMP to 5‘-AMP – Antagonist of Adenylylcyclases ...
THE KOREAN HERBAL PHARMACOPOEIA
... Pharmacopoeia are the title names and the commonly used names adopted in the official monographs. In the official monographs, the titles are accompanied with chemical names or Latin names as the occasion demands. Quasi drugs are excluded from drugs, but general requirements for drugs are similarly a ...
... Pharmacopoeia are the title names and the commonly used names adopted in the official monographs. In the official monographs, the titles are accompanied with chemical names or Latin names as the occasion demands. Quasi drugs are excluded from drugs, but general requirements for drugs are similarly a ...
ANTI MYCOBACTERIAL DRUGS
... Individuals with this latent tuberculosis infection do not have active disease and can not transmit the organism to others. However, reactivation of disease may occur if the host’s immune defenses are impaired. ...
... Individuals with this latent tuberculosis infection do not have active disease and can not transmit the organism to others. However, reactivation of disease may occur if the host’s immune defenses are impaired. ...
KINETICS OF ELIMINATION
... Drugs are administered in such a way so as to maintain a steady state of drug in the body ...
... Drugs are administered in such a way so as to maintain a steady state of drug in the body ...
Drugs Involved in Significant Pharmacokinetic Drug
... This table lists drugs those have been demonstrated or anticipated to be involved in pharmacokinetic drug-drug interactions (DDIs) at therapeutic doses in human, and caused by gastric pH changes, chelate formations or alternations in activity of the drug metabolizing enzymes and transporters. Most o ...
... This table lists drugs those have been demonstrated or anticipated to be involved in pharmacokinetic drug-drug interactions (DDIs) at therapeutic doses in human, and caused by gastric pH changes, chelate formations or alternations in activity of the drug metabolizing enzymes and transporters. Most o ...
Obsessive Compulsive Disorder
... o a tricyclic antidepressant with specific inhibitor of the reuptake of serotonin o increases activity of certain chemicals in the brain o 25mg every day at bedtime ● 1980s controlled o found to be an important advancement o trials then lead to a superior drug ● Fluvoxemine o SSRI (selective seroton ...
... o a tricyclic antidepressant with specific inhibitor of the reuptake of serotonin o increases activity of certain chemicals in the brain o 25mg every day at bedtime ● 1980s controlled o found to be an important advancement o trials then lead to a superior drug ● Fluvoxemine o SSRI (selective seroton ...
gcse biology - School
... Sheet on how do microbes get into the body (Boardworks also good here) http://www.abpischools.org.uk/page/modules/infectiousdiseases_pathogens/pathogens8.cfm? coSiteNavigation_allTopic=1 this site has some good info on bacteria and viruses and a nice animation on how viruses infect cells and multipl ...
... Sheet on how do microbes get into the body (Boardworks also good here) http://www.abpischools.org.uk/page/modules/infectiousdiseases_pathogens/pathogens8.cfm? coSiteNavigation_allTopic=1 this site has some good info on bacteria and viruses and a nice animation on how viruses infect cells and multipl ...
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... to detailed investigation of their structure and pharmacological action. Some of the compounds were found to possess a definite physiological activity and later it was observed that the physiological activity of a compound is associated with a particular structural unit or group and if this structur ...
... to detailed investigation of their structure and pharmacological action. Some of the compounds were found to possess a definite physiological activity and later it was observed that the physiological activity of a compound is associated with a particular structural unit or group and if this structur ...
Krok 2. Pharmacy Клінічна фармація 1 6 months after treatment a
... A 56-year-old patient suffering from essential hypertension was prescribed an inhibitor of angiotensin converting enzyme (ACE) and a potassium-sparing diuretic. Such combination is: A Unreasonable because it increases risk of hyperkaliemia development B Reasonable because it decreases risk of hyperk ...
... A 56-year-old patient suffering from essential hypertension was prescribed an inhibitor of angiotensin converting enzyme (ACE) and a potassium-sparing diuretic. Such combination is: A Unreasonable because it increases risk of hyperkaliemia development B Reasonable because it decreases risk of hyperk ...
Research advances in basic mechanisms of seizures and
... production and metabolism in the central nervous system, large body of evidence has been recently accumulated on the role of GABA receptors in the mechanism of seizures and in the action of antiepileptic drugs. GABA exerts its action via ionotropic GABAA and the metabotropic GABAB receptors. The pen ...
... production and metabolism in the central nervous system, large body of evidence has been recently accumulated on the role of GABA receptors in the mechanism of seizures and in the action of antiepileptic drugs. GABA exerts its action via ionotropic GABAA and the metabotropic GABAB receptors. The pen ...
Pharmacotherapy and Children With Autism Spectrum Disorder: A
... with autism spectrum disorder (ASD; e.g., central nervous system stimulants, noradrenergic reuptake inhibitors, alpha-2 adrenergic agonists, antipsychotics, anticonvulsants, selective serotonin reuptake inhibitors, benzodiazepines) in regard to their mechanism of action, behaviors treated, and poten ...
... with autism spectrum disorder (ASD; e.g., central nervous system stimulants, noradrenergic reuptake inhibitors, alpha-2 adrenergic agonists, antipsychotics, anticonvulsants, selective serotonin reuptake inhibitors, benzodiazepines) in regard to their mechanism of action, behaviors treated, and poten ...
Drug Action Measurement
... …… Potency corresponds to the strength of a drug, while Efficacy corresponds to the effectiveness of a drug. …… e.g., if 1 mg of drug A relieves pain as effectively as 10 mg of drug B, drug A is twice as potent as drug B …… the diuretic furosemide eliminates much more salt and water through urine th ...
... …… Potency corresponds to the strength of a drug, while Efficacy corresponds to the effectiveness of a drug. …… e.g., if 1 mg of drug A relieves pain as effectively as 10 mg of drug B, drug A is twice as potent as drug B …… the diuretic furosemide eliminates much more salt and water through urine th ...
A Matching Law Analysis of the Effect of Amphetamine
... of reinforcement was successively shifted through the following sequence: fixed ratio (FR) 1 response, VR 3 response, VR 5 response, VR 9 response, and VR 15 response. Subjects remained on each schedule for 3 days before advancing to the next schedule. During this period of training on the series of ...
... of reinforcement was successively shifted through the following sequence: fixed ratio (FR) 1 response, VR 3 response, VR 5 response, VR 9 response, and VR 15 response. Subjects remained on each schedule for 3 days before advancing to the next schedule. During this period of training on the series of ...
เภสัชจลนศาสตร์
... Irritating cpds have less effects than other routes – Cons: unretreatable, toxic conc, lipid solvent cannot be given by this route (hemolysis), closely monitored ...
... Irritating cpds have less effects than other routes – Cons: unretreatable, toxic conc, lipid solvent cannot be given by this route (hemolysis), closely monitored ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.