Novel pharmacotherapeutic treatments for cocaine addiction R E V I E W
... cocaine in one subjective measure (P = 0.02). Importantly, this early study suggested safety as well as the possibility of a cocaine-blunting effect with modafinil. In addition to examining the impact of modafinil on the euphorigenic effects of cocaine, early research focused on the similarity of mo ...
... cocaine in one subjective measure (P = 0.02). Importantly, this early study suggested safety as well as the possibility of a cocaine-blunting effect with modafinil. In addition to examining the impact of modafinil on the euphorigenic effects of cocaine, early research focused on the similarity of mo ...
Product Information
... Hypersensitivity to any dihydropyridine or any ingredient of the preparation. Lercanidipine is also contraindicated during pregnancy and during lactation, in women of child-bearing potential unless effective contraception is used, in patients with left ventricular outflow tract obstruction, untreate ...
... Hypersensitivity to any dihydropyridine or any ingredient of the preparation. Lercanidipine is also contraindicated during pregnancy and during lactation, in women of child-bearing potential unless effective contraception is used, in patients with left ventricular outflow tract obstruction, untreate ...
Obsessive-Compulsive Disorder Fact Sheet
... patient gradually experiences less anxiety from the obsessive thoughts and becomes able to refrain from the compulsive actions for extended periods of time. Some patients will not agree to participate in behavior therapy because it can be difficult. Others also have depression, which must be treated ...
... patient gradually experiences less anxiety from the obsessive thoughts and becomes able to refrain from the compulsive actions for extended periods of time. Some patients will not agree to participate in behavior therapy because it can be difficult. Others also have depression, which must be treated ...
Drugs for Neoplasia
... laboratory synthesis. The drugs have diverse actions against Cancer cells, disrupting DNA or RNA production, or having toxic action against metabolic pathways. The result is a slowing or stopping of growth, and/or killing of the cancer cell. Antineoplastic Drugs are more effective against rapidly re ...
... laboratory synthesis. The drugs have diverse actions against Cancer cells, disrupting DNA or RNA production, or having toxic action against metabolic pathways. The result is a slowing or stopping of growth, and/or killing of the cancer cell. Antineoplastic Drugs are more effective against rapidly re ...
Electrophysiological Effects of LU111995 on Canine Hearts: In Vivo
... screw-type electrode (model 6917; Medtronic) was placed in the left ventricle near the apex. The electrode lead was connected to a programmable Medtronic pacemaker (MINIX 8340) that was placed in a s.c. pouch. For studying ERP and for monitoring ventricular conduction time, three platinum bipolar el ...
... screw-type electrode (model 6917; Medtronic) was placed in the left ventricle near the apex. The electrode lead was connected to a programmable Medtronic pacemaker (MINIX 8340) that was placed in a s.c. pouch. For studying ERP and for monitoring ventricular conduction time, three platinum bipolar el ...
Griffin 460 Mobile GC/MS Analysis of Designer
... marketed under the guise of herbal incense and bath salts. The reality is that people have found ways to consume these products for their hallucinogenic affects. K2 and Spice are two herbal incense products marketed as novelties and are labeled “not for human consumption.” The herbal incense contain ...
... marketed under the guise of herbal incense and bath salts. The reality is that people have found ways to consume these products for their hallucinogenic affects. K2 and Spice are two herbal incense products marketed as novelties and are labeled “not for human consumption.” The herbal incense contain ...
The Effect of Cytochrome P450 Metabolism on Drug Response
... CYP2D6, and CYP3A4).13 Drugs that cause CYP450 metabolic drug interactions are referred to as either inhibitors or inducers (Table 110,14-16). Inhibitors block the metabolic activity of one or more CYP450 enzymes. The extent to which an inhibitor affects the metabolism of a drug depends upon factors ...
... CYP2D6, and CYP3A4).13 Drugs that cause CYP450 metabolic drug interactions are referred to as either inhibitors or inducers (Table 110,14-16). Inhibitors block the metabolic activity of one or more CYP450 enzymes. The extent to which an inhibitor affects the metabolism of a drug depends upon factors ...
Legalization Of Drugs: The Myths And The Facts
... that, "The legalization of drugs would put drug dealers out of business."She added that it would also reduce the prison population and create a perpetual source of tax revenue.[27] Former Surgeon General Elders told a National Press Club luncheon,"Sixty percent of violent crimes are drug- or alcohol ...
... that, "The legalization of drugs would put drug dealers out of business."She added that it would also reduce the prison population and create a perpetual source of tax revenue.[27] Former Surgeon General Elders told a National Press Club luncheon,"Sixty percent of violent crimes are drug- or alcohol ...
Anti-TB - PharmaStreet
... •It thus enhances its own metabolism as well as that of many drugs including warfarin, oral contraceptives, corticosteroids, sulfonyl ureas, steroids, HIV protease inhibitors, non nucleoside reverse transcriptase inhibitors(NNRTIs), theophylline,metaprolol,fluconazol,ketoconazole, clarithromycin, ph ...
... •It thus enhances its own metabolism as well as that of many drugs including warfarin, oral contraceptives, corticosteroids, sulfonyl ureas, steroids, HIV protease inhibitors, non nucleoside reverse transcriptase inhibitors(NNRTIs), theophylline,metaprolol,fluconazol,ketoconazole, clarithromycin, ph ...
PROVISIONAL ANSWER KEY NAME OF THE POST
... fission reaction, which then detonates a fusion reaction. It is often referred to as a thermo-nuclear or hydrogen device and has unlimited destructive potential. (B) A fusion reaction is created when the nuclei of two light elements are combined, the reaction resulting in heavier elements fragmentin ...
... fission reaction, which then detonates a fusion reaction. It is often referred to as a thermo-nuclear or hydrogen device and has unlimited destructive potential. (B) A fusion reaction is created when the nuclei of two light elements are combined, the reaction resulting in heavier elements fragmentin ...
Overview of ARV Drug Classes and Individual Drugs
... Enfuvirtide (T-20) or Fuzeon ◦ Injectable drug, twice daily. ◦ Essentially doubles the cost of HIV treatment ◦ Rarely used; less potent than most other available HIV medications ◦ “condom for the HIV virus” Prevents the HIV virus from attaching to the CD4 cell by blocking the attachment of the gp4 ...
... Enfuvirtide (T-20) or Fuzeon ◦ Injectable drug, twice daily. ◦ Essentially doubles the cost of HIV treatment ◦ Rarely used; less potent than most other available HIV medications ◦ “condom for the HIV virus” Prevents the HIV virus from attaching to the CD4 cell by blocking the attachment of the gp4 ...
Dewormer Chart for Goats
... The effectiveness of a dewormer should always be tested before being used by performing a Fecal Egg Count Reduction Test (FECRT) or DrenchRite larval development assay (contact Sue Howell in D ...
... The effectiveness of a dewormer should always be tested before being used by performing a Fecal Egg Count Reduction Test (FECRT) or DrenchRite larval development assay (contact Sue Howell in D ...
tetrahydrogestrinone (THG)
... periods up to 12 days in direct comparison to testosterone propionate (o.1mg/animal/day s. c.): THG induced (a dose dependent) androgenic effect on prostate and vesicular seminales parameters and LH serum levels in doses of 1,3,10mg/animal. This androgenic stimulation could be antagonized by the sim ...
... periods up to 12 days in direct comparison to testosterone propionate (o.1mg/animal/day s. c.): THG induced (a dose dependent) androgenic effect on prostate and vesicular seminales parameters and LH serum levels in doses of 1,3,10mg/animal. This androgenic stimulation could be antagonized by the sim ...
Narcotics and Dangerous Drugs
... – Narcotics are drugs with a depressant effect on the central nervous system. – Euphoria and a general feeling of warmth and well-being are frequently associated with their use. – Used to relieve pain and induce sleep. Copyright ©2008 The McGraw-Hill Companies, Inc. All rights reserved. ...
... – Narcotics are drugs with a depressant effect on the central nervous system. – Euphoria and a general feeling of warmth and well-being are frequently associated with their use. – Used to relieve pain and induce sleep. Copyright ©2008 The McGraw-Hill Companies, Inc. All rights reserved. ...
Objectives Drugs that we use/prescribe Drugs our patients take
... Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus ...
... Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus ...
Understanding Pharmacokinetics & Drug-Drug Interactions
... Timing of in vivo Drug Interaction Studies: General Principles • Amount of data: should be adequate to allow safe conduct of each phase of development – 10 day monotherapy study – interaction data not needed – Phase II/III trials – more data needed • Number of studies: no specific number needed pri ...
... Timing of in vivo Drug Interaction Studies: General Principles • Amount of data: should be adequate to allow safe conduct of each phase of development – 10 day monotherapy study – interaction data not needed – Phase II/III trials – more data needed • Number of studies: no specific number needed pri ...
Q1. Viruses and bacteria cause diseases in humans. (a) Draw a ring
... Before treatment all the mice did badly in memory tests. Half the mice were given a daily dose of caffeine in their drinking water. The dose was equivalent to the amount of caffeine in six cups of coffee for a human. The other mice were given ordinary water. After two months, the caffeine-drinking m ...
... Before treatment all the mice did badly in memory tests. Half the mice were given a daily dose of caffeine in their drinking water. The dose was equivalent to the amount of caffeine in six cups of coffee for a human. The other mice were given ordinary water. After two months, the caffeine-drinking m ...
Non-steroidal Anti-inflammatory Drugs (NSAIDs) Presentation
... Liver and Renal toxicity (hepatoxicity) Renal toxicity is more common than liver toxicity Symptoms include nausea, fatigue, jaundice, right upper quadrant abdominal pain, flu-like symptoms Use caution when administering to those with history of heart failure, hypertension, or kidney disease ...
... Liver and Renal toxicity (hepatoxicity) Renal toxicity is more common than liver toxicity Symptoms include nausea, fatigue, jaundice, right upper quadrant abdominal pain, flu-like symptoms Use caution when administering to those with history of heart failure, hypertension, or kidney disease ...
III Clinical trials
... studies to be under taken to verify that data generated in Indian population is in confirmatory will data already generated abroad. ...
... studies to be under taken to verify that data generated in Indian population is in confirmatory will data already generated abroad. ...
Med-Psych Drug-Drug Interactions Update Triptans
... These modest findings reflect almotriptan’s multiple avenues of metabolism, which allow the drug to be biotransformed despite “roadblocks” at some of its metabolic sites. We could not find case reports or studies concerning triptan use with potent 3A4 inhibitors. We suspect that more potent inhibito ...
... These modest findings reflect almotriptan’s multiple avenues of metabolism, which allow the drug to be biotransformed despite “roadblocks” at some of its metabolic sites. We could not find case reports or studies concerning triptan use with potent 3A4 inhibitors. We suspect that more potent inhibito ...
Incentive Salience and the Transition to Addiction
... unpleasant that an addict would do anything to stop it and so relapse occurs as an escape from withdrawal. All these explanations certainly play a role in relapse, yet several considerations suggest that they leave out many situations where relapse occurs. First, drug pleasure or euphoria certainly ...
... unpleasant that an addict would do anything to stop it and so relapse occurs as an escape from withdrawal. All these explanations certainly play a role in relapse, yet several considerations suggest that they leave out many situations where relapse occurs. First, drug pleasure or euphoria certainly ...
Anti-viral drugs
... • Activity: both influenza A and influenza B viruses. • Early administration is crucial because replication of influenza virus peaks at 24–72 hours after the onset of illness. • Oseltamivir is FDA-approved for patients 1 year and older, whereas zanamivir is approved in patients 7 years or older. ...
... • Activity: both influenza A and influenza B viruses. • Early administration is crucial because replication of influenza virus peaks at 24–72 hours after the onset of illness. • Oseltamivir is FDA-approved for patients 1 year and older, whereas zanamivir is approved in patients 7 years or older. ...
Therapeutic drug monitoring of atypical antipsychotic drugs
... plasma clozapine concentrations confirm the usefulness of TDM. Both the antipsychotic efficacy and the adverse effects of clozapine are positively correlated with the plasma concentration of the drug. Norclozapine is not a useful predictor of therapeutic response (30). Most researchers have found th ...
... plasma clozapine concentrations confirm the usefulness of TDM. Both the antipsychotic efficacy and the adverse effects of clozapine are positively correlated with the plasma concentration of the drug. Norclozapine is not a useful predictor of therapeutic response (30). Most researchers have found th ...
ANAFRANIL® 25 mg Coated tablets, 75 mg Sustained
... administer an antipsychotic agent. After such episodes have subsided, low dose therapy with Anafranil may be resumed if required. In predisposed patients, tricyclic antidepressants may provoke pharmacogenic (delirious) psychoses, particularly at night. These disappear within a few days of withdrawin ...
... administer an antipsychotic agent. After such episodes have subsided, low dose therapy with Anafranil may be resumed if required. In predisposed patients, tricyclic antidepressants may provoke pharmacogenic (delirious) psychoses, particularly at night. These disappear within a few days of withdrawin ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.