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Toward Understanding the Biology of a Complex Phenotype: Rat
Toward Understanding the Biology of a Complex Phenotype: Rat

... weeks before behavioral testing. Although K inney et al. (1999) reported housing lights on at 08:00 hr, the circadian phase in which testing occurred was not clear; in the present study, all testing and drug administration occurred between 10:00 and 17:00 hr. Weiss et al. (1999) recently reported th ...
Lecture notes on Toxicology
Lecture notes on Toxicology

... more chemicals taken together is equivalent to the summation of their individual pharmacological action. ...
Methadone treatment in Victoria User information booklet
Methadone treatment in Victoria User information booklet

... service can speed this up, but it costs more. In some cases, your doctor may have to wait for the results of blood tests before starting you on methadone. Your doctor will start you on a dose of methadone, based on what you have been using and your general physical health. Because methadone can be d ...
Comparison of the effects of cimetidine and hyoscine-n
Comparison of the effects of cimetidine and hyoscine-n

... mediated via alterations in drug absorption, distribution and excretion may also be clinically significant. Cimetidine is an imidazole derivative, H2-receptor antagonist that is used primarily to decrease gastric acid secretion in the management of Peptic ulcer and other acid hypersecretory disorder ...
Activated Charcoal - Paramedic Advantage
Activated Charcoal - Paramedic Advantage

... Precautions: Pregnancy (C), Patient >75 y/o, recent trauma, known bleeding disorders, traumatic CPR Interactions: anticoagulants increase bleeding Routes of Administration: IV Onset & Duration of actions: onset rapid; duration 10min Dosages: ...
cannabis-related shape - Nebraska Council of School Administrators
cannabis-related shape - Nebraska Council of School Administrators

... Teen Marijuana Use: A Growing Problem Despite the negative physical and mental side effects of marijuana, its popularity among the teenage population continues to grow.  In 2012, an average of 3.2 million adolescents used marijuana on any ...
Xenazine® 25 mg
Xenazine® 25 mg

... Tetrabenazine elevates serum prolactin concentrations in humans. Following administration of 25 mg to healthy volunteers, peak plasma prolactin levels increased 4 to 5-fold. Tissue culture experiments indicate that approximately one third of human breast cancers are prolactin-dependent in vitro, a f ...
Caffeine Psychological Effects, Use and Abuse
Caffeine Psychological Effects, Use and Abuse

... disruption. Caffeine decreases five HT turnover in rat brain. Amphetamines do not show the results as demonstrated in this paper, whereas other drugs such as hallucinogens show a similar effect. The implication is that the mechanism of caffeine's action may be similar to hallucinogenic drugs. Effect ...
Japanese Guideline on the Investigation of Drug Interactions, 2014
Japanese Guideline on the Investigation of Drug Interactions, 2014

... 4.1.2. Identification and quantitative evaluation of the major elimination pathway by mass balance studies ...
DOCTORAL THESIS
DOCTORAL THESIS

... (NME) approved by the US Food and Drug Administration (FDA) has not increased accordingly; on the contrary, it has diminished as attrition rates are very high.1 A new molecular entity is defined as a drug that contains no active moiety that has been approved by the Food and Drug Administration (FDA) ...
Treatment of Bronchial Asthma
Treatment of Bronchial Asthma

... induced by many different chemicals (tetrazine, FDC Color #5), and does not involve IgE antibody response. Patients produce high levels of cysteinyl leukotrienes in response to COX inhibitors, probably by shunting of arachidonic acid into leukotriene pathway. Abnormality of the promotor region of th ...
Developing new pharmacotherapies for autism C. Ecker , W. Spooren & D. Murphy
Developing new pharmacotherapies for autism C. Ecker , W. Spooren & D. Murphy

Thyroid medication (desiccated )
Thyroid medication (desiccated )

... T4 in synthetic thyroid preparations to T3. About the only time I find it helpful is for people who are sensitive to Armour Thyroid or for those who have been on synthetic hormones for many years when the benefit for shifting appears to be minimal. I also do not recommend Cytomell, which is a T3 hor ...
2009 St Johns Wort Quality Issues and Active Compounds
2009 St Johns Wort Quality Issues and Active Compounds

... of phase I proteins for rutin, which would lead to an increased bioavailability of simultaneously administered active SJW compounds ...
Analgesia en pacientes con ERC
Analgesia en pacientes con ERC

... Central nervous system: Somnolencia Gastrointestinal: Estreñimiento 1% to 10%: Cardiovascular: Tachycardia or bradycardia, hypotension Central nervous system: Dizziness, lightheadedness, false feeling of well being, malaise, headache, restlessness, paradoxical CNS stimulation, confusion Dermatologic ...
Renal Analgesic Brochure
Renal Analgesic Brochure

... Adverse Effects ...
Clenbuterol and the Horse
Clenbuterol and the Horse

... A large clinical trial of clenbuterol syrup was conducted in COPD-affected horses by Erichsen et al.7 These investigators used a score based on clinical signs of respiratory distress, and administered incremental oral doses of clenbuterol from 0.8 to 3.2 ␮g/kg q 12 h. Twenty-five percent of horses r ...
new zealand data sheet
new zealand data sheet

Analysis of 3, 4-Methylenedioxymethamphetamine (MDMA) and its
Analysis of 3, 4-Methylenedioxymethamphetamine (MDMA) and its

... stance. It shows distinct psychotropic effects, which are different from those of the structurally related stimulant amphetamine or hallucinogenic phenylalkylamines (e.g., 3,4-methylenedioxyamphetamine [MDA]and 3,4,5-trimethoxyphenethylamine [mescaline]) (2-6). MDMA is reported to possess antidepres ...
- Nottingham ePrints
- Nottingham ePrints

... Understanding the modulation of contextual fear learning and memory by the neurotransmitter dopamine is important as it could lead to a greater understanding of the mechanisms underlying anxiety disorders. The effect of D1 receptor antagonism during the contextual fear learning and memory stages was ...
Handbook 1108.1 Controlled Substances Pharmacy
Handbook 1108.1 Controlled Substances Pharmacy

... d. All prescriptions for controlled substances must be stamped with the letter “C,” in red ink, not less than 1 inch high, in the lower right corner, in accordance with 21 CFR 1304.04. NOTE: A waiver from this requirement is identified in 21 CFR 1304.04, if the pharmacy uses an automated system. e. ...
DISSOLUTION PROFILING OF BILAYERED CONVENTIONAL RELEASE PARACETAMOL AND
DISSOLUTION PROFILING OF BILAYERED CONVENTIONAL RELEASE PARACETAMOL AND

... prostaglandin inhibitor in peripheral tissues and possesses no significant ant inflammatory effects. Its one of the most important drugs used for the treatment of mild to moderate pain when an anti inflammatory effect is not necessary. Paracetamol preferred over aspirin as an analgesic antipyretic f ...
Doctoral Thesis
Doctoral Thesis

... discussed, including requirements for them, recent advances and present status of some perspective molecules in clinical and preclinical stages of the investigation and the specific targeting on mycobacteria, a promising contemporary approach. Salicylanilides have revealed a wide spectrum of pharmac ...
Prescribing Information - PI
Prescribing Information - PI

... indicated for the treatment of asthma. BEVESPI AEROSPHERE is contraindicated in patients with hypersensitivity to glycopyrrolate, formoterol fumarate, or to any component of the product [see Warnings and ...
Effects of ivermectin in dairy discharges on terrestrial and aquatic
Effects of ivermectin in dairy discharges on terrestrial and aquatic

... Unmetabolised ivermectin in treated animal faeces can affect dung-dwelling invertebrates and insect species under some circumstances (Wall & Strong 1987; Halley et al. 1993; Floate 1998). This biocidal action could be considered beneficial for the control of pest insects such as stable flies and the ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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