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Neuromuscular junction in health and disease
Neuromuscular junction in health and disease

... MG is the most common disorder affecting the postsynaptic membrane.47 This autoimmune disease has an annual incidence of 0.25 – 2.0 per 100 000 population and a bimodal distribution, tending to affect young women and older men. It appears that the incidence in the latter group is increasing. In the ...
PDF full-Text - Journal of Investigational Allergology and Clinical
PDF full-Text - Journal of Investigational Allergology and Clinical

... and its interaction with active transport pumps such as glycoprotein-P (P-gp) or organic anion transporter proteins (OATP), responsible for the outflow or expulsion of xenobiotics from the CNS [12]. Various 2nd generation AH are substrata of P-gp, which has been related with their low penetration in ...
drugs and the kidney
drugs and the kidney

... drug concentrationtime profile that is ...
Biological Treatments for depression (PPH) 2011
Biological Treatments for depression (PPH) 2011

... The most serious side-effects usually associated with Prozac are fainting and an irregular/fast heartbeat. Allergic reactions to Prozac are unlikely but include rash, itching, swelling, dizziness and trouble breathing. ...
Exposure to antidepressants and the risk of cryptogenic
Exposure to antidepressants and the risk of cryptogenic

... [15]. Briefly, cases were defined as those with a diagnosis of CFA recorded anywhere in the GPRD record, and the date of diagnosis defined as the date of this condition. The authors have previously reviewed hospital clinic letters for a subsample of these cases and established that the diagnosis of ...
Asthma
Asthma

... COPD (seventh most common reason for hospital admission in Canada): Physicians and patients view COPD differently. A 2002 study that showed that because combined therapy with inhaled corticosteroids and long-acting ßagonists produced a larger benefit than either therapy alone, it was easier to noti ...
Cognitive therapies
Cognitive therapies

... we need to compare its effectiveness to the rates of the following: – Normal recovery among untreated people – Recovery due to the placebo effect • In double-blind (neither scientist nor subject know who is getting the real drug) studies, several types of drugs have proven useful in treating psychol ...
proforma for registration of subjects for pg dissertation
proforma for registration of subjects for pg dissertation

... for each formulation. The patients with 25% or less than 25% psoriatic lesions were included for the study.The results are calculated using PASI scoring. Changes in the disease signs and symptoms indicated that both agents have anti psoriatic activity but not with placebo gel. However lesions treate ...
Cognitive therapies
Cognitive therapies

OL Chapter 13 - NSCC NetID: Personal Web Space
OL Chapter 13 - NSCC NetID: Personal Web Space

REFERENCE GUIDE FOR THE PHARMACY LICENSING EXAM
REFERENCE GUIDE FOR THE PHARMACY LICENSING EXAM

... patients who are at high risk for perioperative blood loss from elective, noncardiac, nonvascular surgery. 3). In clinical studies, patients experienced greater risks for death, serious cardiovascular events, and stroke when administered erythropoiesis-stimulating agents (ESAs) to target hemoglobin ...
Marijuana in Pregnancy - ANNALS Academy of Medicine Singapore
Marijuana in Pregnancy - ANNALS Academy of Medicine Singapore

... situations, such as request for labour analgesia. Substances most commonly used in pregnancy include ethanol, tobacco, caffeine, marijuana, cocaine, amphetamines and opioids. Poly-substance abuse is very common.1,12 The majority of patients with a history of drug abuse or substance addiction deny it ...
Dr E Harrop – Spasticity, Dystonia and Symptom Management in
Dr E Harrop – Spasticity, Dystonia and Symptom Management in

... • The Care Team / parents have already tried giving these staggered and also more slowly – to limited avail • He now has a PEG-J tube for his feed – how can we rationalise his medication schedule to minimise reflux / vomits? • He is on Movicol (Paed), baclofen, ranitidine and diazepam – what would y ...
Calgon, take me away….
Calgon, take me away….

... • Many patients report adverse effects lasting for days • Panic attacks and prolonged anxiety may occur at higher doses and with regular use ...
Antiamoebic Drugs
Antiamoebic Drugs

...  Protozoa are eukaryotes, the unicellular protozoal cells have metabolic processes closer to those of the human host than to prokaryotic bacterial pathogens. ...
Testing for Overdose of Acetaminophen
Testing for Overdose of Acetaminophen

... and excreted via the kidneys and can be detected in urine for several days after an exposure. While there is a lack of correlation between urine drug concentration and impairment, urine drug screening offers the advantages of noninvasive collection and relatively easy, cost-effective, proven detecti ...
Antihistamine - People Server at UNCW
Antihistamine - People Server at UNCW

... • 1938: President Roosevelt signed the Federal Food, Drug and Cosmetic Act into law. This law required new drugs to be tested for safety before marketing, the results of which would be submitted to FDA in a new drug application (NDA). The law also required that drugs have adequate labeling for safe ...
a review on drug approval process for us, europe and india
a review on drug approval process for us, europe and india

... different regulatory requirements for approval of new drug. For marketing authorization application (MAA) a single regulatory approach is applicable to various countries is almost a difficult task. Therefore it is necessary to have knowledge about regulatory requirement for MAA of each country. The ...
spinraza
spinraza

... • Thrombocytopenia and nephrotoxicity are potential complications associated with nusinersen therapy • Common side effects include respiratory ...
TARGETED DRUG DELIVERY FOR CENTRAL NERVOUS SYSTEM: A REVIEW Research Article
TARGETED DRUG DELIVERY FOR CENTRAL NERVOUS SYSTEM: A REVIEW Research Article

united states securities and exchange commission - corporate
united states securities and exchange commission - corporate

How does it work? What does it mean?
How does it work? What does it mean?

... then in the context of social stimuli, whether physical or emotional, magnocellular OXT neurons might be activated. Such activation would result in release from terminals in the pituitary as well as from some dendrites or collaterals that project into the brain. It will be important for investigator ...
Assessing Impairment from Opioids and Polypharmacy
Assessing Impairment from Opioids and Polypharmacy

... Encourage treating doctors who prescribe narcotic medications to frequently have the patient tested to ensure that the drug is in the patient’s system and in the intended amount. ...
Forensic Toxicology
Forensic Toxicology

...  Many (most?) of the pesticides we spray on our lawns, gardens, etc. are poisonous  Growing in popularity  Easy to obtain  Common enough that it won’t raise suspicions as quickly if traces found ...
“The Comparative Efficacy of Citrus Fragrance and Fluoxetine in the
“The Comparative Efficacy of Citrus Fragrance and Fluoxetine in the

... The results of this study showed that taking CF could improve MDD symptoms in the 6 weeks of treatment and its effects were comparable with effects of Fluoxetine. These results confirmed the research hypothesis. Taking 10 drops of CF was more effective than 20 mg of Fluoxetine after 6 weeks, but the ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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