Phencyclidine (PCP) - Center for Substance Abuse Research
... PCP disrupts the functioning of receptors for the neurotransmitter glutamate, which plays a major role in the perception of pain as well as in learning, memory, and emotion. It also influences the actions of the neurotransmitter dopamine, which causes the euphoria associated with drug use.16 Addicti ...
... PCP disrupts the functioning of receptors for the neurotransmitter glutamate, which plays a major role in the perception of pain as well as in learning, memory, and emotion. It also influences the actions of the neurotransmitter dopamine, which causes the euphoria associated with drug use.16 Addicti ...
Your slides - Learning
... Antecedent liver injury and the use of potentially hepatotoxic drugs 6. Diagnosis of drug-induced liver disease 7. Management of drug-induced liver disease ...
... Antecedent liver injury and the use of potentially hepatotoxic drugs 6. Diagnosis of drug-induced liver disease 7. Management of drug-induced liver disease ...
Withdrawal - Calgary Emergency Medicine
... – Cessation/reduction of heavy/prolonged alcohol use resulting in the development of two or more of the following: ANS hyperactivity, increased hand tremor, insomnia, N, V, transient hallucinations, psychomotor agitation, anxiety, sz, affected global function ...
... – Cessation/reduction of heavy/prolonged alcohol use resulting in the development of two or more of the following: ANS hyperactivity, increased hand tremor, insomnia, N, V, transient hallucinations, psychomotor agitation, anxiety, sz, affected global function ...
Pharma. MCQs
... Which of the following statements best describes the mechanism of action of benzodiazepines? a. Benzodiazepines activate GABAB -receptors in the spinal cord. b. They inhibit GABA-transaminase leading to increased levels of GABA. c. They block glutamate receptors in hierarchical neuronal pathways in ...
... Which of the following statements best describes the mechanism of action of benzodiazepines? a. Benzodiazepines activate GABAB -receptors in the spinal cord. b. They inhibit GABA-transaminase leading to increased levels of GABA. c. They block glutamate receptors in hierarchical neuronal pathways in ...
Logistic Regression Part 2
... Strength: balances risk factors across all groups => equal socio-demographic characteristics => equal health status, health behaviors => equal pre-clinical and clinical disease risk factors ...
... Strength: balances risk factors across all groups => equal socio-demographic characteristics => equal health status, health behaviors => equal pre-clinical and clinical disease risk factors ...
EPILEPSY
... • There is loss of consciousness during the seizure. • The tonic phase, consisting of increased muscle tone (rigidity), is followed by The Clonic phase, which involves jerking of the ...
... • There is loss of consciousness during the seizure. • The tonic phase, consisting of increased muscle tone (rigidity), is followed by The Clonic phase, which involves jerking of the ...
Relative Reinforcing Effects of Cocaine, Remifentanil, and Their
... heroin) produced the same reinforcing effect as would be anticipated by simple addition of effects. This combination also produced a leftward shift in the heroin dose-response function of percentage of drug choice over food, rate of responding, and total reinforcers. The majority of these studies in ...
... heroin) produced the same reinforcing effect as would be anticipated by simple addition of effects. This combination also produced a leftward shift in the heroin dose-response function of percentage of drug choice over food, rate of responding, and total reinforcers. The majority of these studies in ...
Location of enkephalinase and functional effects of
... FC in the SO of the same magnitude as those produced by morphine. These effects exclude ketamine as an appropriate anaesthetic agent when studying opiates in vivo. Dose-response analysis for [Leu'lenkephalin demonstrated that the feline SO is highly sensitive to this drug and that the effect is medi ...
... FC in the SO of the same magnitude as those produced by morphine. These effects exclude ketamine as an appropriate anaesthetic agent when studying opiates in vivo. Dose-response analysis for [Leu'lenkephalin demonstrated that the feline SO is highly sensitive to this drug and that the effect is medi ...
Diagnosis & Management of Dementia
... Not used anymore Prototypical cholinesterase inhibitor for the treatment of Alzheimer's disease ...
... Not used anymore Prototypical cholinesterase inhibitor for the treatment of Alzheimer's disease ...
Herb-Drug Interactions The Good, The Bad and The Ugly
... extract, in far greater concentration that would occur with oral doses, had MAOI activity • R. rosea extracts in therapeutic doses contain such small amounts of MAOIs that they have no clinical significance when taken by mouth • R. rosea has been combined with all classes of antidepressants (except ...
... extract, in far greater concentration that would occur with oral doses, had MAOI activity • R. rosea extracts in therapeutic doses contain such small amounts of MAOIs that they have no clinical significance when taken by mouth • R. rosea has been combined with all classes of antidepressants (except ...
Insomnia Final - The Rx Consultant
... Individuals with insomnia may have difficulty falling or staying asleep, or feel unrefreshed from sleep despite having adequate opportunity to sleep. Up to half of all adults complain of occasional trouble sleeping in any given year. About 10-25% have chronic symptoms with serious daytime consequenc ...
... Individuals with insomnia may have difficulty falling or staying asleep, or feel unrefreshed from sleep despite having adequate opportunity to sleep. Up to half of all adults complain of occasional trouble sleeping in any given year. About 10-25% have chronic symptoms with serious daytime consequenc ...
melatonin - don`t lose sleep over it 1
... for 4 to 5 hours after taking melatonin.11 There have also been reports of transient anxiety, irritability and confusion.1 Note: Melatonin used in excessive doses can lead to receptor desensitization and exacerbate the condition that is being treated.3 ...
... for 4 to 5 hours after taking melatonin.11 There have also been reports of transient anxiety, irritability and confusion.1 Note: Melatonin used in excessive doses can lead to receptor desensitization and exacerbate the condition that is being treated.3 ...
The Development of New Therapeutics for Alzheimerʼns Disease
... disease-modifying agents for the treatment of AD are now neuropharmacologic research priorities.4–6 Molecular Neuropathology of Ad ...
... disease-modifying agents for the treatment of AD are now neuropharmacologic research priorities.4–6 Molecular Neuropathology of Ad ...
Nikch, Hargrave, Devans SC Doyle ,* ,,&torneys and Counselors
... (11, there are limited data about the toxic effects of PPA when taken in overdose ...
... (11, there are limited data about the toxic effects of PPA when taken in overdose ...
Anti-platelet agents
... Platelet surface receptor, receptor for fibrinogen and von willebrand factor,which anchors platelets to foreign surface and each other thereby mediating aggregation. Receptor is activated by TXA2, Collagen, and thrombin to developbinding sites for its ligands. Inhibition of binding to this receptor ...
... Platelet surface receptor, receptor for fibrinogen and von willebrand factor,which anchors platelets to foreign surface and each other thereby mediating aggregation. Receptor is activated by TXA2, Collagen, and thrombin to developbinding sites for its ligands. Inhibition of binding to this receptor ...
STATUS OF FIXED DOSE DRUG COMBINATION IN ANTIDIABETIC DRUG
... • Without significant increase in clinically important side effects. ...
... • Without significant increase in clinically important side effects. ...
Clinical evaluation of colon specific drug delivery
... Oral controlled drug deliveys system ADVANTAGES: Increased patient compliance Reduction in dosing frequency Reduced fluctuations in circulatory drug levels Employ less total drug and eliminate local side effects Better utilization of the drugs More uniform effect Better control over th ...
... Oral controlled drug deliveys system ADVANTAGES: Increased patient compliance Reduction in dosing frequency Reduced fluctuations in circulatory drug levels Employ less total drug and eliminate local side effects Better utilization of the drugs More uniform effect Better control over th ...
Analgesia Quiz
... CT scans are not routinely recommended as there is a high prevalence of disc abnormalities on CT in patients without back pain. ...
... CT scans are not routinely recommended as there is a high prevalence of disc abnormalities on CT in patients without back pain. ...
Obstetric Analgesia and Anesthesia
... stretching of the perineum S2,3,4 this can be blocked by an epidural block but may inhibit the pushing effort Bupivicaine and Chlorprocaine have become the agents of choice for epidural anesthesia (IV of either can cause cardiac collapse and death ...
... stretching of the perineum S2,3,4 this can be blocked by an epidural block but may inhibit the pushing effort Bupivicaine and Chlorprocaine have become the agents of choice for epidural anesthesia (IV of either can cause cardiac collapse and death ...
The Food and Drug Administration (FDA) - Overview
... producers meet certain standards, FDA protects consumers and enables them to know what they're buying. For example, the agency requires that drugs--both prescription and over-the-counter--be proven safe and effective. In deciding whether to approve new drugs, FDA does not itself do research, but rat ...
... producers meet certain standards, FDA protects consumers and enables them to know what they're buying. For example, the agency requires that drugs--both prescription and over-the-counter--be proven safe and effective. In deciding whether to approve new drugs, FDA does not itself do research, but rat ...
PATIENT INFORMATION SHEET CHRONIC MIGRAINE
... exam, etc). I normally suggest that acute attack medication (e.g. painkiller + domperidone, or triptan drug) is strictly limited to such circumstances (but ideally no more than 2-3 times per year, and definitely less than once every month or two). By using such acute attack medications, patients ris ...
... exam, etc). I normally suggest that acute attack medication (e.g. painkiller + domperidone, or triptan drug) is strictly limited to such circumstances (but ideally no more than 2-3 times per year, and definitely less than once every month or two). By using such acute attack medications, patients ris ...
Drug Main action Side effects Notes
... membranes or BBB. - Excreted unchanged. - Calcium channel blockers and aminoglycosides enhance their action. - Depolarizing blocker. - Agonist that leads to desensitization of the receptor. - Doesn’t respond to AchE. -Short onset of action. - Given IV. - Doesn’t penetrate membranes or BBB. - Excrete ...
... membranes or BBB. - Excreted unchanged. - Calcium channel blockers and aminoglycosides enhance their action. - Depolarizing blocker. - Agonist that leads to desensitization of the receptor. - Doesn’t respond to AchE. -Short onset of action. - Given IV. - Doesn’t penetrate membranes or BBB. - Excrete ...
Oral Drugs for Type 2 For complete drug information, see the
... takes 4 to 6 weeks to see an effect on blood glucose. Advantages: May improve HDL (“good”) cholesterol and triglycerides. Possible side effects: Can cause weight gain and fluid retention. Caution: These drugs can cause heart failure. People with heart failure and those at risk for heart failure shou ...
... takes 4 to 6 weeks to see an effect on blood glucose. Advantages: May improve HDL (“good”) cholesterol and triglycerides. Possible side effects: Can cause weight gain and fluid retention. Caution: These drugs can cause heart failure. People with heart failure and those at risk for heart failure shou ...
... modem clinical description was given by JoNES et al. [2] of Liverpool, UK in 1962. Exercise is acknowledged by many paediatricians to be the most common cause for an attack of asttuna in child-ren, and the presence of EIA is diagnostic of asthma. Using standardized protocols for exercise challenge, ...
Notes - ADHD Association of Greater Edmonton
... Absenteeism and productivity levels affected at work. 2 to 4 times as many motor accidents. ...
... Absenteeism and productivity levels affected at work. 2 to 4 times as many motor accidents. ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.