Parkinson`s disease
... Rationale for drug use • Provide symptomatic relief. • No agent has been proven to slow progression of disease. • Treatment does not alter progression and individual response can be variable, such as in benign tremulous Parkinson’s disease where the tremor may respond poorly, but usually progresses ...
... Rationale for drug use • Provide symptomatic relief. • No agent has been proven to slow progression of disease. • Treatment does not alter progression and individual response can be variable, such as in benign tremulous Parkinson’s disease where the tremor may respond poorly, but usually progresses ...
Tuberculosis: New Drug Discovery Pipelines
... microti, Mycobacterium canettii, Mycobacterium caprae and Mycobacterium pinnipedii are also known to cause the disease. Pathogenesis of TB [14] The steps in TB pathogensis are – exposure, infection, disease and death. Infection with Mtb can be pulmonary or extra pulmonary (affecting other parts of t ...
... microti, Mycobacterium canettii, Mycobacterium caprae and Mycobacterium pinnipedii are also known to cause the disease. Pathogenesis of TB [14] The steps in TB pathogensis are – exposure, infection, disease and death. Infection with Mtb can be pulmonary or extra pulmonary (affecting other parts of t ...
Read the updated advice - Association of Paediatric Anaesthetists
... administered outside the hospital in children with proven sleep apnoea from sleep studies or a strong history of respiratory symptoms during sleep (observed airway obstruction and or respiratory pause). In an ...
... administered outside the hospital in children with proven sleep apnoea from sleep studies or a strong history of respiratory symptoms during sleep (observed airway obstruction and or respiratory pause). In an ...
Drugs and the Drug Laws: Historical and Cultural Contexts
... abuse and it is important not to underestimate the earnestness and legitimacy of many governmental efforts to address very real societal dangers linked to substance abuse. It is equally important, however, to recognize that societies’ historical reactions to drugs and drug-related activity have aris ...
... abuse and it is important not to underestimate the earnestness and legitimacy of many governmental efforts to address very real societal dangers linked to substance abuse. It is equally important, however, to recognize that societies’ historical reactions to drugs and drug-related activity have aris ...
Glutamate receptors, microtubule associated proteins and
... McDonald & Johnstone (1990); both NMDA and non-NMDA receptors have protean roles in neurodevelopment. For example, NMDA receptors promote granule-cell survival (Balazs et al. 1988) and non-NMDA receptors promote synaptogenesis (Mattson et al. 19886). Glutamate stimulates protein synthesis in develop ...
... McDonald & Johnstone (1990); both NMDA and non-NMDA receptors have protean roles in neurodevelopment. For example, NMDA receptors promote granule-cell survival (Balazs et al. 1988) and non-NMDA receptors promote synaptogenesis (Mattson et al. 19886). Glutamate stimulates protein synthesis in develop ...
Herbals – Herbal Secrets –Watchout
... Fish oil is oil derived from the tissues of oily fish. Fish oils contain the omega-3 fatty acids eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), precursors of eicosanoids that are known to reduce inflammation throughout the body, and are thought to have many health benefits. Studies sug ...
... Fish oil is oil derived from the tissues of oily fish. Fish oils contain the omega-3 fatty acids eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), precursors of eicosanoids that are known to reduce inflammation throughout the body, and are thought to have many health benefits. Studies sug ...
Melatonin - Nutritional Frontiers
... synthesized from the amino acid tryptophan by the pineal gland in the back of the brain. • Most of the research on melatonin has focused on its role in maintaining normal sleep/wake rhythms. The rise in plasma melatonin levels is thought to be responsible for bringing on sleep. Nocturnal melatonin p ...
... synthesized from the amino acid tryptophan by the pineal gland in the back of the brain. • Most of the research on melatonin has focused on its role in maintaining normal sleep/wake rhythms. The rise in plasma melatonin levels is thought to be responsible for bringing on sleep. Nocturnal melatonin p ...
ImmuTest Drug/Adulterant Screen Card
... Cocaine is a potent central nervous system stimulant and a local anesthetic found in the leaves of the coca plant. The psychological effects induced by using cocaine are euphoria, confidence and sense of increased energy. These psychological effects are accompanied by increased heart rate, dilation ...
... Cocaine is a potent central nervous system stimulant and a local anesthetic found in the leaves of the coca plant. The psychological effects induced by using cocaine are euphoria, confidence and sense of increased energy. These psychological effects are accompanied by increased heart rate, dilation ...
NOURIAST Tablets 20 mg
... By 18 days after oral administration, 38.9% of the radioactivity was recovered in urine and 48.0% in feces (data in non-Japanese)8). A study using a Caco-2 cell monolayer demonstrated inhibitory effect of istradefylline on P-glycoprotein. 5. Pharmacokinetics in Patients with Hepatic Impairment9) Ste ...
... By 18 days after oral administration, 38.9% of the radioactivity was recovered in urine and 48.0% in feces (data in non-Japanese)8). A study using a Caco-2 cell monolayer demonstrated inhibitory effect of istradefylline on P-glycoprotein. 5. Pharmacokinetics in Patients with Hepatic Impairment9) Ste ...
Is Addiction Really a “Disease?”
... Mice studies separate correlation from causation Addiction can exist where “behavioral” variables do not apply Moral, personality, and social learning variables can sometimes go along with addiction ...
... Mice studies separate correlation from causation Addiction can exist where “behavioral” variables do not apply Moral, personality, and social learning variables can sometimes go along with addiction ...
Updating the Beers Criteria for Potentially Inappropriate Medication
... lems in elderly patients, including the use of lists containing specific drugs to avoid in the elderly and appropriateness indexes applied by pharmacists or clinicians.1,10,11 Systematic review of the evidence-based literature on medication use in elderly patients is another approach to defining th ...
... lems in elderly patients, including the use of lists containing specific drugs to avoid in the elderly and appropriateness indexes applied by pharmacists or clinicians.1,10,11 Systematic review of the evidence-based literature on medication use in elderly patients is another approach to defining th ...
Rx FACTS October 2003
... The World Health Organization reported approximately 50% of people are non-compliant in taking their prescription medications. Doctors believe this may explain why some drugs do well in clinical trials but are not as effective once they are approved. The percentage of non-compliance appears to be th ...
... The World Health Organization reported approximately 50% of people are non-compliant in taking their prescription medications. Doctors believe this may explain why some drugs do well in clinical trials but are not as effective once they are approved. The percentage of non-compliance appears to be th ...
Prototype drug - s3.amazonaws.com
... Triggered by diet, injury, or other stress Attacks often occur at night ...
... Triggered by diet, injury, or other stress Attacks often occur at night ...
ABCs of Psychiatric Medication
... immediate attention so that they can call the doctor in the event that you are unable to seek treatment on your own. Different types of drugs are formulated differently. Fluoxetine, Dothiepin, Nortriptyline, and Duloxetine come in capsule form and should be swallowed whole. Venlafaxine and Bupropion ...
... immediate attention so that they can call the doctor in the event that you are unable to seek treatment on your own. Different types of drugs are formulated differently. Fluoxetine, Dothiepin, Nortriptyline, and Duloxetine come in capsule form and should be swallowed whole. Venlafaxine and Bupropion ...
Clinical pharmacology of facilities used at the diseases of
... A. Quinidine prolongs repolarization and the effective refractory period. B. Mexiletine shortens repolarization and decreases the effective refractory period. C. *Propranolol increases Phase 4 depolarization. D. Verapamil shortens the duration of the action potential. E. Amiodarone prolongs repolari ...
... A. Quinidine prolongs repolarization and the effective refractory period. B. Mexiletine shortens repolarization and decreases the effective refractory period. C. *Propranolol increases Phase 4 depolarization. D. Verapamil shortens the duration of the action potential. E. Amiodarone prolongs repolari ...
COOCH2CH2(OCH2CH2)n OCH3 CH3(CH2)2CH2NH
... Intentional and unintentional overdose may result in death, particularly in children. The drug is chemically related to tetracaine and other topical anesthetics and shares various aspects of their pharmacology and toxicology. Drugs of this type are generally well absorbed after ingestion. Signs and ...
... Intentional and unintentional overdose may result in death, particularly in children. The drug is chemically related to tetracaine and other topical anesthetics and shares various aspects of their pharmacology and toxicology. Drugs of this type are generally well absorbed after ingestion. Signs and ...
Drugs from nature" past achievements, future prospects
... Other significant drugs developed from traditional medicinal plants include: the antihypertensive agent, reserpine, isolated from Rauwolfia serpentina used in Ayurvedic medicine for the treatment of snakebite and other ailments; 4 ephedrine, first isolated in 1887 from Ephedra sinica (Ma Huang), a p ...
... Other significant drugs developed from traditional medicinal plants include: the antihypertensive agent, reserpine, isolated from Rauwolfia serpentina used in Ayurvedic medicine for the treatment of snakebite and other ailments; 4 ephedrine, first isolated in 1887 from Ephedra sinica (Ma Huang), a p ...
20150108- biOasis Q1 - IR Presentation.pptx
... Exploits a natural, biological process to deliver medicines into the brain tissue by linking preexisting drugs to a human protein that freely crosses the BBB through receptors located on the brain capillary wall in a process called Receptor Mediated Transcytosis. ...
... Exploits a natural, biological process to deliver medicines into the brain tissue by linking preexisting drugs to a human protein that freely crosses the BBB through receptors located on the brain capillary wall in a process called Receptor Mediated Transcytosis. ...
Marijuana Background As a word, marijuana is less than a hundred
... blood-brain barrier and into the brain. There, THC attaches to sites on nerve cells, affecting the way those cells work. As THC enters the brain, it causes a user to feel “high” by attaching to sites on nerve cells and changing brain chemistry, specifically in parts of the brain that regu- late move ...
... blood-brain barrier and into the brain. There, THC attaches to sites on nerve cells, affecting the way those cells work. As THC enters the brain, it causes a user to feel “high” by attaching to sites on nerve cells and changing brain chemistry, specifically in parts of the brain that regu- late move ...
Potent synthetic cannabinoid smoking mixtures
... Tolerance to synthetic cannabinoids develops quickly, with increasing dosage and compulsive use commonly reported. It is not thought that synthetic cannabinoids produce physical dependence, but like natural cannabis some people may become anxious about stopping and may experience mild withdrawal sym ...
... Tolerance to synthetic cannabinoids develops quickly, with increasing dosage and compulsive use commonly reported. It is not thought that synthetic cannabinoids produce physical dependence, but like natural cannabis some people may become anxious about stopping and may experience mild withdrawal sym ...
HYPERTENSION IN ICU
... Phentolamine-nonselective-1-10mg I.v. boluses,530mg/hr Phenoxybenzamine-nonselective-1mg/kg/day Labetolol-α1, α2,β1- 20-80mg I.v boluses,0.54mg/min infusion Prazosin- α1—2-10mg/day,8th hourly Carvedilol –oral preparation Side effects Can cause tachycardia, idiosyncratic hypotension ...
... Phentolamine-nonselective-1-10mg I.v. boluses,530mg/hr Phenoxybenzamine-nonselective-1mg/kg/day Labetolol-α1, α2,β1- 20-80mg I.v boluses,0.54mg/min infusion Prazosin- α1—2-10mg/day,8th hourly Carvedilol –oral preparation Side effects Can cause tachycardia, idiosyncratic hypotension ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.