PDF - Pharmacological Reviews
... C. Truth or fallacy and its consequences. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . D. An approach for extinguishing controversies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . II. Theoretical basis for d ...
... C. Truth or fallacy and its consequences. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . D. An approach for extinguishing controversies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . II. Theoretical basis for d ...
Syed Fatehyab Ali Address - Dottorato in Neuroscienze
... The International Drug Abuse Research Society (Co-founder) International Brain Research Organization (IBRO) International Society for Neurochemistry International Society for Developmental Neuroscience Society of Toxicology (USA) Society for Neuroscience (USA) Founder Member of Society of Toxicology ...
... The International Drug Abuse Research Society (Co-founder) International Brain Research Organization (IBRO) International Society for Neurochemistry International Society for Developmental Neuroscience Society of Toxicology (USA) Society for Neuroscience (USA) Founder Member of Society of Toxicology ...
Organic Anion Transporters and Their Implications in
... these features allow OATs to mediate drug-drug interactions during competition of two or more agents for the same transporter and mediate cellular toxicity as a result of transporting cytotoxic drugs (Koepsell and Endou, 2004; Rizwan and Burckhardt, 2007). These factors imply that OATs have a fundam ...
... these features allow OATs to mediate drug-drug interactions during competition of two or more agents for the same transporter and mediate cellular toxicity as a result of transporting cytotoxic drugs (Koepsell and Endou, 2004; Rizwan and Burckhardt, 2007). These factors imply that OATs have a fundam ...
Research Article www.ijrap.net
... A simple and reproducible U.V. spectrophotometric method for the quantitative determination of Curcumin and Quercetin in Madhujeevan churna (MJC) was developed and validated. The hydroalcoholic extract of developed churna was obtained by continuous heat extraction method. The method was validated us ...
... A simple and reproducible U.V. spectrophotometric method for the quantitative determination of Curcumin and Quercetin in Madhujeevan churna (MJC) was developed and validated. The hydroalcoholic extract of developed churna was obtained by continuous heat extraction method. The method was validated us ...
A Closer Look at the Risks vs. Benefits of Kava (Piper methysticum)
... treatments used in the study, the treatments with the best evidence of effectiveness for anxiety were Kava, exercise, and relaxation training. The study included a description of evidence for at least 16 homeopathic remedies. 19 Another recent review (2012), conducted a literature search for complem ...
... treatments used in the study, the treatments with the best evidence of effectiveness for anxiety were Kava, exercise, and relaxation training. The study included a description of evidence for at least 16 homeopathic remedies. 19 Another recent review (2012), conducted a literature search for complem ...
Dynorphin A1–13 Stimulates Ovine Fetal Pituitary
... To determine whether dynorphin A1–13 is acting via the hypothalamic secretagogues, CRF or AVP, some fetuses were pretreated with antagonists of CRF or AVP before dynorphin A1–13 administration. a-Helical CRF [Sigma Chemical Co,, St. Louis, MO; 20 mg icv followed by 10 mg/hr icv infusion (Bennet et a ...
... To determine whether dynorphin A1–13 is acting via the hypothalamic secretagogues, CRF or AVP, some fetuses were pretreated with antagonists of CRF or AVP before dynorphin A1–13 administration. a-Helical CRF [Sigma Chemical Co,, St. Louis, MO; 20 mg icv followed by 10 mg/hr icv infusion (Bennet et a ...
Bodybuilders - What Kind of Risk are These?
... and duration can increase. In addition, non-medical steroid use by adolescents correlates with poorer attitudes related to health(8). Please note that some of these side effects can be seen in non-steroid-using athletes, but steroid use may accelerate the process. Also note that steroids can have a ...
... and duration can increase. In addition, non-medical steroid use by adolescents correlates with poorer attitudes related to health(8). Please note that some of these side effects can be seen in non-steroid-using athletes, but steroid use may accelerate the process. Also note that steroids can have a ...
TYLENOL® with Codeine
... The minimum effective analgesic concentration will vary widely among patients, especially among patients who have been previously treated with potent agonist opioids. The minimum effective analgesic concentration of codeine for any individual patient may increase over time due to an increase in pain ...
... The minimum effective analgesic concentration will vary widely among patients, especially among patients who have been previously treated with potent agonist opioids. The minimum effective analgesic concentration of codeine for any individual patient may increase over time due to an increase in pain ...
Ketoconazole and Itraconazole Pharmacokinetic
... cyclosporine, phenytoin and warfarin. It is therefore, possible that the increases in AUC0-∞, Cmax, tl/2 and MRT, seen in this study, when CIP was given together with KTC may be due to the inhibition of cytochromes by KTC. Similarly the fluoroquinolone antibiotics cause both class-specific and agent ...
... cyclosporine, phenytoin and warfarin. It is therefore, possible that the increases in AUC0-∞, Cmax, tl/2 and MRT, seen in this study, when CIP was given together with KTC may be due to the inhibition of cytochromes by KTC. Similarly the fluoroquinolone antibiotics cause both class-specific and agent ...
product monograph
... RISPERDAL CONSTA® (risperidone) powder for injectable prolonged-release suspension is indicated for the management of the manifestations of schizophrenia and related psychotic disorders. RISPERDAL CONSTA® was found to improve both positive and negative symptoms of schizophrenia. The efficacy of RISP ...
... RISPERDAL CONSTA® (risperidone) powder for injectable prolonged-release suspension is indicated for the management of the manifestations of schizophrenia and related psychotic disorders. RISPERDAL CONSTA® was found to improve both positive and negative symptoms of schizophrenia. The efficacy of RISP ...
ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS
... cautiously so as to prevent withdrawal symptoms and to prevent a return to illicit drug use. If the treatment is continued, hepatic function should be monitored closely. As buprenorphine is an opioid, pain as a symptom of a disease may be attenuated. Athletes must be aware that this medicine may cau ...
... cautiously so as to prevent withdrawal symptoms and to prevent a return to illicit drug use. If the treatment is continued, hepatic function should be monitored closely. As buprenorphine is an opioid, pain as a symptom of a disease may be attenuated. Athletes must be aware that this medicine may cau ...
The Psychology of Chocolate
... chocolate works more indirectly to produce its 'high'. As well as anandamide itself, chocolate contains two chemicals known to slow the breakdown of anandamide. Chocolate might therefore work by prolonging the action of this natural stimulant in the brain. The animation below shows how this could wo ...
... chocolate works more indirectly to produce its 'high'. As well as anandamide itself, chocolate contains two chemicals known to slow the breakdown of anandamide. Chocolate might therefore work by prolonging the action of this natural stimulant in the brain. The animation below shows how this could wo ...
Gamma-butyrolactone (GBL) - World Health Organization
... Schedule II of the 1971 Convention. GHB is easily synthesized from GBL by changing the pH with addition of an alkali (e.g. sodium hydroxide), and recipes and "kits" have been provided on the Internet identifying or providing the ingredients to do so. Synthetic conversion of GBL to make GHB is unnece ...
... Schedule II of the 1971 Convention. GHB is easily synthesized from GBL by changing the pH with addition of an alkali (e.g. sodium hydroxide), and recipes and "kits" have been provided on the Internet identifying or providing the ingredients to do so. Synthetic conversion of GBL to make GHB is unnece ...
Model-based Analysis of the Effects of Thioridazine Enantiomers on the... Papillary Action Potential
... by ICaL inhibition. Using the inverse method, the levels of IKr inhibition determined at higher doses were very similar to those found using the forward method. However, the shortening observed at 0.1 mg L-1 meant that zero IKr inhibition was determined. In addition, even attributing ICaL inhibition ...
... by ICaL inhibition. Using the inverse method, the levels of IKr inhibition determined at higher doses were very similar to those found using the forward method. However, the shortening observed at 0.1 mg L-1 meant that zero IKr inhibition was determined. In addition, even attributing ICaL inhibition ...
Albuterol Sulfate Inhalation Solution 0.5%
... population of beta2-receptors in the human heart existing in a concentration between 10% and 50%. The precise function of these receptors has not been established. In controlled clinical trials, albuterol has been shown to have more effect on the respiratory tract, in the form of bronchial smooth mu ...
... population of beta2-receptors in the human heart existing in a concentration between 10% and 50%. The precise function of these receptors has not been established. In controlled clinical trials, albuterol has been shown to have more effect on the respiratory tract, in the form of bronchial smooth mu ...
Review articles Treatment of Myoclonus
... replicate clinically (Flicker and Grimley Evans, 1999). Piracetam, the first of the class, was developed by pioneering research by C. Giurgea in the late 1960s ; it was he who coined the term “nootropic”, to mean enhancement of learning and memory. The term is sometimes extended to include other act ...
... replicate clinically (Flicker and Grimley Evans, 1999). Piracetam, the first of the class, was developed by pioneering research by C. Giurgea in the late 1960s ; it was he who coined the term “nootropic”, to mean enhancement of learning and memory. The term is sometimes extended to include other act ...
Martindale: The Complete Drug Reference
... Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with diclofenac in doses of 10 to 25 mg1 and the UK CSM has received a report of an aspirinsensitive patient who died from acute asthma 4 hours after a single 25-mg dos ...
... Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with diclofenac in doses of 10 to 25 mg1 and the UK CSM has received a report of an aspirinsensitive patient who died from acute asthma 4 hours after a single 25-mg dos ...
Min2008 online
... Fragile X (FX) mice display an increased susceptibility to audiogenic seizures (‘‘AGS’’) (Chen and Toth, 2001; Musumeci et al., 2000). The intensity and population frequency of such seizures is affected by the mouse strain background (Yan et al., 2004). Use of the fmr1tm1Cgr (FX) allele in the more ...
... Fragile X (FX) mice display an increased susceptibility to audiogenic seizures (‘‘AGS’’) (Chen and Toth, 2001; Musumeci et al., 2000). The intensity and population frequency of such seizures is affected by the mouse strain background (Yan et al., 2004). Use of the fmr1tm1Cgr (FX) allele in the more ...
Depakene/Depakote/ Depakote
... Depakene (valproic acid) and Depakote (divalproex sodium) are better known as anticonvulsants—medications for treating epilepsy. This may present some confusion for patients, as well as their families, when they are prescribed an anticonvulsant without a history of seizures. In the past decade, anti ...
... Depakene (valproic acid) and Depakote (divalproex sodium) are better known as anticonvulsants—medications for treating epilepsy. This may present some confusion for patients, as well as their families, when they are prescribed an anticonvulsant without a history of seizures. In the past decade, anti ...
Simvastatin
... levels and in such patients measurements should be repeated promptly and then performed more frequently. If the transaminase levels show evidence of progression, particularly if they rise to three times the upper limit of normal and are persistent, the drug should be discontinued. Liver biopsy shoul ...
... levels and in such patients measurements should be repeated promptly and then performed more frequently. If the transaminase levels show evidence of progression, particularly if they rise to three times the upper limit of normal and are persistent, the drug should be discontinued. Liver biopsy shoul ...
Albuterol Sulfate Inhalation Solution 0.083%
... monoamine oxidase inhibitors or tricyclic anti-depressants, since the action of albuterol on the vascular system may be potentiated. Beta-receptor blocking agents and albuterol inhibit the effect of each other. Carcinogenesis, Mutagenesis, and Impairment of Fertility: Albuterol sulfate caused a sign ...
... monoamine oxidase inhibitors or tricyclic anti-depressants, since the action of albuterol on the vascular system may be potentiated. Beta-receptor blocking agents and albuterol inhibit the effect of each other. Carcinogenesis, Mutagenesis, and Impairment of Fertility: Albuterol sulfate caused a sign ...
Diphenhydramine versus nonsedating antihistamines for acute
... Despite the known sedative effects, diphenhydramine remains the most commonly used antihistamine in the ED for the treatment for acute allergic reactions.6,7 In a recent multicenter study of food-related allergic reactions in the ED, 72% of patients received antihistamines, with 90% receiving diphen ...
... Despite the known sedative effects, diphenhydramine remains the most commonly used antihistamine in the ED for the treatment for acute allergic reactions.6,7 In a recent multicenter study of food-related allergic reactions in the ED, 72% of patients received antihistamines, with 90% receiving diphen ...
1 Hepatoprotective effect of silymarin (Silybum marianum) on
... The liver is involved in detoxification and elimination of drugs and a liver injury could affects pharmacokinetics parameters of drugs, and increases the risk of adverse drug-effects. Liver injuries induced by APAP is one of the best characterized system of xenobiotic-induced hepatotoxicity. It is c ...
... The liver is involved in detoxification and elimination of drugs and a liver injury could affects pharmacokinetics parameters of drugs, and increases the risk of adverse drug-effects. Liver injuries induced by APAP is one of the best characterized system of xenobiotic-induced hepatotoxicity. It is c ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.