NON-INFECTIOUS DISEASES
... Leukotriene antagonists (e.g. montelukast, zafirlukast) Glucocorticosteroids Many available for oral or aeorosol use (AEROSOL: beclamethasone, budesonide. fluticasone, triamcinolone, mometasone, ciclesonide – ORAL: prednisone, methylprednisolone, cortisone) ...
... Leukotriene antagonists (e.g. montelukast, zafirlukast) Glucocorticosteroids Many available for oral or aeorosol use (AEROSOL: beclamethasone, budesonide. fluticasone, triamcinolone, mometasone, ciclesonide – ORAL: prednisone, methylprednisolone, cortisone) ...
Chapter 4
... Distribution of drugs within the body Several factors determine the rate at which a drug in the bloodstream reaches sites of action within the brain: Lipid solubility: BBB blocks only water-soluble molecules; thus, lipidsoluble molecules can pass into brain and distribute themselves Depot bi ...
... Distribution of drugs within the body Several factors determine the rate at which a drug in the bloodstream reaches sites of action within the brain: Lipid solubility: BBB blocks only water-soluble molecules; thus, lipidsoluble molecules can pass into brain and distribute themselves Depot bi ...
CHEMICAL SIGNALLING IN THE NERVOUS SYSTEM
... partly by neurons and partly by astrocytes, which convert it to glutamine. Astrocytes release glutamine via a transporter, and neurons take it up and synthesise glutamate. ...
... partly by neurons and partly by astrocytes, which convert it to glutamine. Astrocytes release glutamine via a transporter, and neurons take it up and synthesise glutamate. ...
fff-Antipsychotics (Neuroleptics)
... 1. A straight chain of three carbon atoms linking the basic ring nitrogen with a carbon, nitrogen, or oxygen atom.This atom may be a part of benzoyl group,phenothiazine or thioxanthene (tricyclic system). Y = C, N, O ...
... 1. A straight chain of three carbon atoms linking the basic ring nitrogen with a carbon, nitrogen, or oxygen atom.This atom may be a part of benzoyl group,phenothiazine or thioxanthene (tricyclic system). Y = C, N, O ...
Darifenacin Hydrobromide
... significantly affect anticholinergic receptor activity and selectivity; ...
... significantly affect anticholinergic receptor activity and selectivity; ...
Neuronal function
... A) Autoreceptors and pre-synaptic inhibition 6. Neurotransmitters A) Receptors B) Distribution in brain C) Drug actions Read Kalat chapter 2 and 3 _________________________________________________________________________ Important neuron parts: Dendrites Soma or Cell Body (contains axon hillock) Axo ...
... A) Autoreceptors and pre-synaptic inhibition 6. Neurotransmitters A) Receptors B) Distribution in brain C) Drug actions Read Kalat chapter 2 and 3 _________________________________________________________________________ Important neuron parts: Dendrites Soma or Cell Body (contains axon hillock) Axo ...
Document
... receptors on the receiving neurons their effect may be either excitatory (making the cell more likely to fire) or inhibitory (making the cell less likely to fire). • Neurotransmitters that are not accepted by the receptor sites must be removed from the synapse in order for the next potential stimula ...
... receptors on the receiving neurons their effect may be either excitatory (making the cell more likely to fire) or inhibitory (making the cell less likely to fire). • Neurotransmitters that are not accepted by the receptor sites must be removed from the synapse in order for the next potential stimula ...
Quiz 1 Key - chem.uwec.edu
... 1. On a single graph, draw a typical dose/response curve for the new natural product drug, hartseloic acid. Also draw dose/response curve for the drug in the presence of (A) , a competitive antagonist and (B) a non-competitive antagonist. In addition, include a curve for a newly discovered similar d ...
... 1. On a single graph, draw a typical dose/response curve for the new natural product drug, hartseloic acid. Also draw dose/response curve for the drug in the presence of (A) , a competitive antagonist and (B) a non-competitive antagonist. In addition, include a curve for a newly discovered similar d ...
Evidence for the Existence of Nonmonotonic Dose
... • All complex biological systems do violate the assumptions necessary for receptor occupancy theory to accurately describe the concentration response relationships for many drug, natural and synthetic compounds • Many natural or synthetic compounds (i.e. EDCs) are likely nonselective or have variabl ...
... • All complex biological systems do violate the assumptions necessary for receptor occupancy theory to accurately describe the concentration response relationships for many drug, natural and synthetic compounds • Many natural or synthetic compounds (i.e. EDCs) are likely nonselective or have variabl ...
Pharmacology of the Autonomic Nervous System
... reduced. A clinically useful inhibitor of this enzyme is metyrosine (a-methyl-p-tyrosine). Dopa decarboxylase (dopa to dopamine) is found in the cytoplasm of many nonneural as well as neural tissues and had been called "aromatic-L-amino acid decarboxylase" because of its broad substrate specificity. ...
... reduced. A clinically useful inhibitor of this enzyme is metyrosine (a-methyl-p-tyrosine). Dopa decarboxylase (dopa to dopamine) is found in the cytoplasm of many nonneural as well as neural tissues and had been called "aromatic-L-amino acid decarboxylase" because of its broad substrate specificity. ...
BDS Ist YEAR EXAMINATION 2008-09
... Describe various mechanism of drug action with suitable example. ...
... Describe various mechanism of drug action with suitable example. ...
T5_a: High resolution copy of the slides of the talk
... Chronic or habitual use of any chemical substance to alter states of body or mind for other than medically warranted purposes. Psychological dependence is the subjective feeling that the user needs the drug to maintain a feeling of well‐being; physical dependence is characterized by tolerance (t ...
... Chronic or habitual use of any chemical substance to alter states of body or mind for other than medically warranted purposes. Psychological dependence is the subjective feeling that the user needs the drug to maintain a feeling of well‐being; physical dependence is characterized by tolerance (t ...
Nicotinic agonist
A nicotinic agonist is a drug that mimics the action of acetylcholine (ACh) at nicotinic acetylcholine receptors (nAChRs). The nAChR is named for its affinity for nicotine.Examples include nicotine (by definition), acetylcholine (the endogenous agonist of nAChRs), choline, epibatidine, lobeline, varenicline and cytisine.