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Terms and symbols - Guide to Pharmacology
Terms and symbols - Guide to Pharmacology

New Drug Update
New Drug Update

... • Acute decompensate heart failure • Blood pressure less than 90/50 ...
563-2180-2-SP - Iranian Journal of Kidney Diseases
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... the morbidity rate of these patients (1). In 1980, it was first recognized that excreting of albumin even in lesser amounts (which can be evaluated by sensitive protein measuring methods ) may be regarded as an important predicting factor in renal insufficiency of patients with types I and II diabet ...
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Cross-Regional Webinar on Synthetic Cannabinoids
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... expression in the large intestine.3 While PGE2 gastroprotective action is mediated by EP1, the healing-promoting action of PGE2 in the stomach is mediated by the EP4 receptor.4 In the kidney, the PGE2 antinatiuretic effect is mediated by the EP4 receptor.5 EP4 receptors are abundantly expressed in t ...
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Antifungal Agents

... • The basic structural requirement is weak basic imidazole ring or 1,2,4-triazole ring bonded by N-C linkage to rest structure. • At molecular level N3 of imidazole and N4 of triazole bind to the heme iron of enzyme CYP450 to inhibit activation of molecular oxygen. • Most potent azole possess 2 or 3 ...
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`Spice` and other herbal blends: harmless incense or cannabinoid

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2. Virtual Screening of Molecular Properties and Bioactivity Score of

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Pharmacology of the Autonomic Nervous System

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Predicting new molecular targets for known drugs

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Atacand Product Information

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Name: Date: ______ 1. All of the following are
Name: Date: ______ 1. All of the following are

Interaction of Plant Extracts with Central Nervous System Receptors
Interaction of Plant Extracts with Central Nervous System Receptors

< 1 ... 42 43 44 45 46 47 48 49 50 ... 85 >

Discovery and development of angiotensin receptor blockers

The angiotensin receptor blockers (ARBs), also called angiotensin (AT1) receptor antagonists or sartans, are a group of antihypertensive drugs that act by blocking the effects of the hormone angiotensin II (Ang II) in the body, thereby lowering blood pressure. Their structure is similar to Ang II and they bind to Ang II receptors as inhibitors, e.g., [T24 from Rhys Healthcare].ARBs are widely used drugs in the clinical setting today, their main indications being mild to moderate hypertension, chronic heart failure, secondary stroke prevention and diabetic nephropathy.The discovery and development of ARBs is a demonstrative example of modern rational drug design and how design can be used to gain further knowledge of physiological systems, in this case, the characterization of the subtypes of Ang II receptors.
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