Higher medication doses in heart failure?
... based in part on non–dose-response HF studies.9-11 ...
... based in part on non–dose-response HF studies.9-11 ...
“Decoding” Food Labels
... Omapatrilat (Vanlev from Bristol-Meyers Squibb) combines 2 effects: it blocks ACE and it inhibits neutral endopeptidase (NEP), to keep atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) levels up. ANP & BNP work to get rid of sodium (and thus excess fluid), lower blood pressure, an ...
... Omapatrilat (Vanlev from Bristol-Meyers Squibb) combines 2 effects: it blocks ACE and it inhibits neutral endopeptidase (NEP), to keep atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) levels up. ANP & BNP work to get rid of sodium (and thus excess fluid), lower blood pressure, an ...
hypnotics and sedatives
... • structurally unrelated to each other and to benzodiazepines • therapeutic efficacy as hypnotics is due to agonist effects on the benzodiazepine site of the GABAA receptor • Compared to benzodiazepines, Z compounds are -less effective as anticonvulsants or muscle relaxants -which may be related to ...
... • structurally unrelated to each other and to benzodiazepines • therapeutic efficacy as hypnotics is due to agonist effects on the benzodiazepine site of the GABAA receptor • Compared to benzodiazepines, Z compounds are -less effective as anticonvulsants or muscle relaxants -which may be related to ...
classical vs. neuropeptides
... 2. Autoreceptor: refers to transmitter receptors, on or near presynaptic terminals, which are sensitive to the transmitter(s) released by the terminal itself •Classification by transduction mechanism 1. Ligand-gated channels: - either excitatory or inhibitory actions - rapid action & rapidly reversi ...
... 2. Autoreceptor: refers to transmitter receptors, on or near presynaptic terminals, which are sensitive to the transmitter(s) released by the terminal itself •Classification by transduction mechanism 1. Ligand-gated channels: - either excitatory or inhibitory actions - rapid action & rapidly reversi ...
Bromo-DragonFly
... synthetised in 1998, when it was used to investigate the structure and activity of the brain’s serotonin receptors as part of animal studies. In Finland, Bromo-DragonFly was first intercepted in early 2007. It momentarily generated a lot of buzz on a variety of online drug forums, after which intere ...
... synthetised in 1998, when it was used to investigate the structure and activity of the brain’s serotonin receptors as part of animal studies. In Finland, Bromo-DragonFly was first intercepted in early 2007. It momentarily generated a lot of buzz on a variety of online drug forums, after which intere ...
LÉČIVA OVLIVŇUJÍCÍ CHOLINERGNÍ RECEPTORY
... low dose (less than 0.5 mg) (result of central vagal stimulation + block of presynaptic M-autoreceptor inhibitory effects); as the muscarinic (M2) receptors on the SA node are blocked by higher concentrations of atropine, tachycardia results - at therapeutic doses – atropine has only mild effect on ...
... low dose (less than 0.5 mg) (result of central vagal stimulation + block of presynaptic M-autoreceptor inhibitory effects); as the muscarinic (M2) receptors on the SA node are blocked by higher concentrations of atropine, tachycardia results - at therapeutic doses – atropine has only mild effect on ...
