Microbial Diseases of the Nervous System
... (farms, horse trails, even if animals have not been around recently). • Symptoms: toxin causes rigid paralysis. Death occurs from suffocation (“lockjaw” prevents mouth from opening). ...
... (farms, horse trails, even if animals have not been around recently). • Symptoms: toxin causes rigid paralysis. Death occurs from suffocation (“lockjaw” prevents mouth from opening). ...
ACUTE FLACCID PARALYSIS (AFP)
... AFP (acute flaccid paralysis) is a universal abbreviation because it is very imp. as it can be caused by several disorders such as botulism, polio... AFP is the acute onset of generalized flaccid weakness in the absence of symptoms of encephalopathy, it implicates the motor unit so we mean a lower m ...
... AFP (acute flaccid paralysis) is a universal abbreviation because it is very imp. as it can be caused by several disorders such as botulism, polio... AFP is the acute onset of generalized flaccid weakness in the absence of symptoms of encephalopathy, it implicates the motor unit so we mean a lower m ...
Control of Communicable Diseases Manual
... In wound botulism the same clinical picture is seen after the causative organism contaminates a wound in which anaerobic conditions develop. Intestinal (infant) botulism is the most common form of botulism in the USA; it results from ingestion of Clostridium botulinum spores with subsequent outgrowt ...
... In wound botulism the same clinical picture is seen after the causative organism contaminates a wound in which anaerobic conditions develop. Intestinal (infant) botulism is the most common form of botulism in the USA; it results from ingestion of Clostridium botulinum spores with subsequent outgrowt ...
... characterized by constipation, poor feeding, and failure to thrive that may be followed by progressive weakness, impaired respiration, and death. Physician awareness of infant botulism is paramount to early recognition and intervention, because more than 70 percent of these infants will eventually r ...
Bioterrorism Readiness Plan
... • usually non-fatal if treated with antibiotics and a 25% mortality rate if untreated Gastro-intestinal Anthrax (ingestion) • bloody diarrhea, hematemesis • + blood cultures after 2-3 days • usually fatal ( almost 100% mortality) after progression to toxemia and sepsis ...
... • usually non-fatal if treated with antibiotics and a 25% mortality rate if untreated Gastro-intestinal Anthrax (ingestion) • bloody diarrhea, hematemesis • + blood cultures after 2-3 days • usually fatal ( almost 100% mortality) after progression to toxemia and sepsis ...
Overview of Category A Bioterrorism Agents
... Botulism ~ Clostridium botulinum • Spore-forming bacteria; found naturally in soil • Produces most poisonous substance known • Toxins are colorless, odorless, tasteless • Inactivated by heat (> 85°C for 5 min) ...
... Botulism ~ Clostridium botulinum • Spore-forming bacteria; found naturally in soil • Produces most poisonous substance known • Toxins are colorless, odorless, tasteless • Inactivated by heat (> 85°C for 5 min) ...
#1 - School of Public Health
... Botulism ~ Clostridium botulinum • Spore-forming bacteria; found naturally in soil • Produces most poisonous substance known • Toxins are colorless, odorless, tasteless • Inactivated by heat (> 85°C for 5 min) ...
... Botulism ~ Clostridium botulinum • Spore-forming bacteria; found naturally in soil • Produces most poisonous substance known • Toxins are colorless, odorless, tasteless • Inactivated by heat (> 85°C for 5 min) ...
Biological Threats - Georgia Poison Center
... – Absorbed via mucosal surface or wound, not intact skin – Interferes with nerve transmission Æ paralysis ...
... – Absorbed via mucosal surface or wound, not intact skin – Interferes with nerve transmission Æ paralysis ...
Carcinogens:
... Click here for a list of toxins as determined by the State of California and the EPA: pdf ACUTELY TOXIC SUBSTANCES Acutely toxic substances produce adverse effects when exposed individuals receive only small doses of that substance for a short period of time. (e.g. hydrogen fluoride). Substances wit ...
... Click here for a list of toxins as determined by the State of California and the EPA: pdf ACUTELY TOXIC SUBSTANCES Acutely toxic substances produce adverse effects when exposed individuals receive only small doses of that substance for a short period of time. (e.g. hydrogen fluoride). Substances wit ...
Biological Warfare Agents
... Clostridium botulinum: from soil into food (home canned food, foiled wrapped potatoes, garlic in oil, yoghurt, cream cheese, infant formula, cream cheese) / wound toxin absorbed; major potential in bioterrorism, inhaled; most poisonous substance known to man; no human-human spread; toxin in blood ...
... Clostridium botulinum: from soil into food (home canned food, foiled wrapped potatoes, garlic in oil, yoghurt, cream cheese, infant formula, cream cheese) / wound toxin absorbed; major potential in bioterrorism, inhaled; most poisonous substance known to man; no human-human spread; toxin in blood ...
Bioterrorism: Key Facts about Anthrax, Smallpox, Plague and Botulism
... and wear a face mask for the first two days of treatment. There is no available effective vaccine. 4. BOTULISM Botulism is caused by ingestion of the toxin produced by Clostridium botulinum, or by formation of the toxin by bacteria infecting a wound or the gastrointestinal tract. Botulinum toxin can ...
... and wear a face mask for the first two days of treatment. There is no available effective vaccine. 4. BOTULISM Botulism is caused by ingestion of the toxin produced by Clostridium botulinum, or by formation of the toxin by bacteria infecting a wound or the gastrointestinal tract. Botulinum toxin can ...
Bioterrorism PP
... • Incubation period: – Neurological S/S for food borne botulism – 12-36 hours after ingestion – Neurological S/S for inhalation botulism – 24-72 hours after exposure ...
... • Incubation period: – Neurological S/S for food borne botulism – 12-36 hours after ingestion – Neurological S/S for inhalation botulism – 24-72 hours after exposure ...
File
... • Clostridium botulinum – rare but severe intoxication usually from home canned food • C. botulinum is distributed throughout the environment. The spores find their way into preserved or canned foods with low oxygen levels and nutrients that support growth. • Seven antigenic varieties of toxin (A–G) ...
... • Clostridium botulinum – rare but severe intoxication usually from home canned food • C. botulinum is distributed throughout the environment. The spores find their way into preserved or canned foods with low oxygen levels and nutrients that support growth. • Seven antigenic varieties of toxin (A–G) ...
Syndrom of diarrhea
... • Most common from home-canned foods – Asparagus, green beans, beets, corn, baked potatoes, garlic, chile peppers, tomatoes; type A – Improperly fermented fish (Alaska); type E ...
... • Most common from home-canned foods – Asparagus, green beans, beets, corn, baked potatoes, garlic, chile peppers, tomatoes; type A – Improperly fermented fish (Alaska); type E ...
Chapter 5 ( Contd.)
... toxin, causes serious paralytic illness. Botulinic toxin is a powerful known toxins: about one microgram is lethal to humans. It blocks nerve function and leads to respiratory and musculoskeletal paralysis. ...
... toxin, causes serious paralytic illness. Botulinic toxin is a powerful known toxins: about one microgram is lethal to humans. It blocks nerve function and leads to respiratory and musculoskeletal paralysis. ...
Type E botulism associated with fish product - EFSA
... Five cases of botulism caused by botulinum neurotoxin type E (BoNT E) have been diagnosed in November 2016 in two countries: three cases in males in Germany and two cases in partners (one male and one female) in Spain. Two German and two Spanish cases had symptom onset in early November and the thir ...
... Five cases of botulism caused by botulinum neurotoxin type E (BoNT E) have been diagnosed in November 2016 in two countries: three cases in males in Germany and two cases in partners (one male and one female) in Spain. Two German and two Spanish cases had symptom onset in early November and the thir ...
clostridium botulinum - World Health Organization
... nerves usually beginning with cranial nerves. It occurs when neuromuscular transmission is interrupted by a protein neurotoxin produced by the spore-forming, obligate anaerobic bacterium Clostridium botulinum. Paralysis begins with the cranial nerves, then affects the upper extremities, the respirat ...
... nerves usually beginning with cranial nerves. It occurs when neuromuscular transmission is interrupted by a protein neurotoxin produced by the spore-forming, obligate anaerobic bacterium Clostridium botulinum. Paralysis begins with the cranial nerves, then affects the upper extremities, the respirat ...
Chapter 19
... intoxication usually from home canned food • Clostridium perfringens – mild intestinal illness; second most common form of food poisoning worldwide ...
... intoxication usually from home canned food • Clostridium perfringens – mild intestinal illness; second most common form of food poisoning worldwide ...
Microviewer and microscope for pathogens and
... f) Look at slide #6. This is Clostridium botulinum, the bacteria that cause botulism – a very severe and deadly type of food poisoning. The botulinum toxin is one of the deadliest toxins known. Draw what you see in the microviewer. The round structures are spores. Label your diagram. ...
... f) Look at slide #6. This is Clostridium botulinum, the bacteria that cause botulism – a very severe and deadly type of food poisoning. The botulinum toxin is one of the deadliest toxins known. Draw what you see in the microviewer. The round structures are spores. Label your diagram. ...
Gram positive pathogens
... Based on the signs and symptoms of the disease Loss of sensation in skin lesions in the case of ...
... Based on the signs and symptoms of the disease Loss of sensation in skin lesions in the case of ...
Recognition and Management of Bioterrorism Agents
... Know treatment/prophylaxis of BT agents Know how to report suspected BT cases Help protect your facility from contamination ...
... Know treatment/prophylaxis of BT agents Know how to report suspected BT cases Help protect your facility from contamination ...
Chapter 19
... • Tetanospasmin – neurotoxin causes paralysis by binding to motor nerve endings; blocking the release of neurotransmitter for muscular contraction inhibition; muscles contract uncontrollably • Death most often due to paralysis of respiratory muscles ...
... • Tetanospasmin – neurotoxin causes paralysis by binding to motor nerve endings; blocking the release of neurotransmitter for muscular contraction inhibition; muscles contract uncontrollably • Death most often due to paralysis of respiratory muscles ...
Botulism
Botulism US /ˈbɒtʃʉlɪzəm/ UK /ˈbɒtjʊlɪzəm/ (Latin, botulus, a sausage) is a rare and potentially fatal illness caused by a toxin produced by the bacterium Clostridium botulinum. The disease begins with weakness, trouble seeing, feeling tired, and trouble speaking. This may then be followed by weakness of the arms, chest muscles, and legs. The disease does not usually affect consciousness or cause a fever.Botulism can occur in a few different ways. The bacterial spores that cause it are common in both soil and water. They produce botulinum toxin when exposed to low oxygen levels and certain temperatures. Foodborne botulism happens when food containing the toxin is eaten. Infant botulism happens when the bacteria develops in the intestines and releases toxin. Typically this only happens in children less than six months of age as after that protective mechanisms develop. Wound botulism is found most often among those who inject street drugs. In this situation spores enter a wound and, in the absence of oxygen, release toxin. It is not passed directly between people. The diagnosis is confirmed by finding the toxin or bacteria in the person in question.Prevention is primarily by proper food preparation. The toxin, though not the organism, is destroyed by heating to more than 85 °C (185 °F) for longer than 5 minutes. Honey can contain the organism, and for this reason honey should not be fed to children of under 12 months. Treatment is with an antitoxin. In those who lose their ability to breathe on their own, mechanical ventilation, potentially for months may be required. Antibiotics may be used for wound botulism. Death occurs in 5 to 10% of people. Botulism can affect many other animals.