Lecture-Oxidative Phsphorylation
... Oxidative Phosphorylation What is mitochondria? 2 membranes: Inner - only permeable to O2, H2O transporters req’d for ATP, Pi, pyruvate, etc. folding increases surface area (site of ox. phos. machinery) Matrix contains: citric acid cycle enzymes Fatty acid oxidation enzymes (discuss later) ...
... Oxidative Phosphorylation What is mitochondria? 2 membranes: Inner - only permeable to O2, H2O transporters req’d for ATP, Pi, pyruvate, etc. folding increases surface area (site of ox. phos. machinery) Matrix contains: citric acid cycle enzymes Fatty acid oxidation enzymes (discuss later) ...
ENZYMES
... MICHAELIS-MENTEN EQUATION -the rate equation for a one-substrate enzyme catalyzed reaction. ...
... MICHAELIS-MENTEN EQUATION -the rate equation for a one-substrate enzyme catalyzed reaction. ...
Bioinformatics Analysis of Phenylacetaldehyde Synthase (PAAS), a
... or primary structure of a protein is the most important indication for its function. However, it is approved that prediction of protein characteristics from the primary amino acid sequence is not possible directly. Therefore, methods to predict protein characteristics have converged on tertiary and ...
... or primary structure of a protein is the most important indication for its function. However, it is approved that prediction of protein characteristics from the primary amino acid sequence is not possible directly. Therefore, methods to predict protein characteristics have converged on tertiary and ...
Chapter 7 - Medical Image Analysis
... regulation of the activity of transporters and enzymes involved in glucose and fatty acid metabolism in skeletal muscle. We know that the activity of transporters and enzymes is not only modulated by means of phosphorylation/dephosphorylation, but also by translocation from one subcellular compartme ...
... regulation of the activity of transporters and enzymes involved in glucose and fatty acid metabolism in skeletal muscle. We know that the activity of transporters and enzymes is not only modulated by means of phosphorylation/dephosphorylation, but also by translocation from one subcellular compartme ...
Biochemistry 6/e
... Hormone-sensitive lipases convert TAGs to free fatty acids and glycerol. At low carbohydrate and low insulin concentrations, TAG hydrolysis is stimulated by increased epinephrine and glucagon which activate Protein kinase A through Gprotein transduction. ...
... Hormone-sensitive lipases convert TAGs to free fatty acids and glycerol. At low carbohydrate and low insulin concentrations, TAG hydrolysis is stimulated by increased epinephrine and glucagon which activate Protein kinase A through Gprotein transduction. ...
A Protein Factor in the Nutrition of Paramecium
... Island, New York, U.S.A., but not all of these proved adaptable to artificial media. Suitable strains were obtained by selecting individuals from cultures containing the natural bacterial flora and washing them by a modification of the Parpart (1928) technique previously published (Kidder, Lilly & C ...
... Island, New York, U.S.A., but not all of these proved adaptable to artificial media. Suitable strains were obtained by selecting individuals from cultures containing the natural bacterial flora and washing them by a modification of the Parpart (1928) technique previously published (Kidder, Lilly & C ...
Divergence and Convergence in Enzyme Evolution
... group of the second substrate (27). Until recently, the only deviations from this pattern were succinyl-CoA synthetase and pyruvate-phosphate dikinase, which form phosphohistidine intermediates that are attacked by a thiol or carbonyl group, respectively. However, two newly described ATP-grasp enzym ...
... group of the second substrate (27). Until recently, the only deviations from this pattern were succinyl-CoA synthetase and pyruvate-phosphate dikinase, which form phosphohistidine intermediates that are attacked by a thiol or carbonyl group, respectively. However, two newly described ATP-grasp enzym ...
Lipid Transport & Storage
... Brown adipose tissue is involved in metabolism particularly at times when heat generation is necessary ...
... Brown adipose tissue is involved in metabolism particularly at times when heat generation is necessary ...
Role of the ubiquitinselective CDC48UFD1/NPL4 chaperone
... signi®cantly stabilized in all three mutants. But since the CDC48UFD1/NPL4 complex is essential for the production of UFAs (Rape et al., 2001), we considered the possibility that the observed stabilization might be caused by UFA depletion. However, as shown in Figure 3B, addition of oleic acid had e ...
... signi®cantly stabilized in all three mutants. But since the CDC48UFD1/NPL4 complex is essential for the production of UFAs (Rape et al., 2001), we considered the possibility that the observed stabilization might be caused by UFA depletion. However, as shown in Figure 3B, addition of oleic acid had e ...
Structure and physical-chemical properties of enzymes
... veegatable pepsin for digesion of proteins. These enzymes help loosen nercotic and encrusted waste material from the intestinal walls.Pepsina proteolytic enzyme that breaks down proteins into peptides. Can digest 3500 times its weight in proteins.Proteasedigests proteinsRenninhelps digest cow's milk ...
... veegatable pepsin for digesion of proteins. These enzymes help loosen nercotic and encrusted waste material from the intestinal walls.Pepsina proteolytic enzyme that breaks down proteins into peptides. Can digest 3500 times its weight in proteins.Proteasedigests proteinsRenninhelps digest cow's milk ...
Quiz - Columbus Labs
... MWC Heterotropic allosteric effects: “K” The linked equilibria lead to changes in the relative amounts of R and T and, therefore, shifts in the substrate saturation curve. This behavior, depicted by the graph, defines an allosteric “K” system. The parameters of such a system are: (1) S and A (or I) ...
... MWC Heterotropic allosteric effects: “K” The linked equilibria lead to changes in the relative amounts of R and T and, therefore, shifts in the substrate saturation curve. This behavior, depicted by the graph, defines an allosteric “K” system. The parameters of such a system are: (1) S and A (or I) ...
Sporopollenin biosynthetic enzymes interact and constitute a
... polymerisation in the microspore walls are not known. In Arabidopsis anther, secretion into the locule may involve the ABC transporter ABCG26/WBC27 (Choi et al., 2011; Dou et al., 2011; Quilichini et al., 2010). In rice, lipid transfer proteins (LTPs) have been shown to be required for exine formati ...
... polymerisation in the microspore walls are not known. In Arabidopsis anther, secretion into the locule may involve the ABC transporter ABCG26/WBC27 (Choi et al., 2011; Dou et al., 2011; Quilichini et al., 2010). In rice, lipid transfer proteins (LTPs) have been shown to be required for exine formati ...
Regulation of metabolic pathways at the cellular level
... Overview of the lecture • Overview of regulation of metabolic pathways – regulation of respiratory chain and aerobic phosphorylation – regulation of the Krebs cycle – regulation of the oxidative decarboxylation of pyruvate – regulation of glycolysis and gluconeogenesis – regulation of glycogen meta ...
... Overview of the lecture • Overview of regulation of metabolic pathways – regulation of respiratory chain and aerobic phosphorylation – regulation of the Krebs cycle – regulation of the oxidative decarboxylation of pyruvate – regulation of glycolysis and gluconeogenesis – regulation of glycogen meta ...
Compartmentalisation of metabolic pathways
... capacity to synthesize fat – fasting: ↓in quantity of lipogenetic enzymes; enzymes of gluconeogenesis are induced (↑synthesis) ...
... capacity to synthesize fat – fasting: ↓in quantity of lipogenetic enzymes; enzymes of gluconeogenesis are induced (↑synthesis) ...
Lipid metabolism
... Endogenous: In all cell. Liver is responsible for plasma phospholipids synthesis and degradation Plasma levels: The average total phospholipids are about 200 mg/dl (60% lecithins, 25% cephalins and 15% sphingomyelins). Digestion and absorption: begins in the intestine Phospholipids reaching the inte ...
... Endogenous: In all cell. Liver is responsible for plasma phospholipids synthesis and degradation Plasma levels: The average total phospholipids are about 200 mg/dl (60% lecithins, 25% cephalins and 15% sphingomyelins). Digestion and absorption: begins in the intestine Phospholipids reaching the inte ...
Ch 19 - Chemistry Courses: About
... • Looks allosteric, but this is monomeric enzyme • May be due to conformational change upon product release— stays in active state at high concentration of glucose ...
... • Looks allosteric, but this is monomeric enzyme • May be due to conformational change upon product release— stays in active state at high concentration of glucose ...
Presentation
... • Elimination of water from C-2 and C-3 yields the enol-phosphate PEP • PEP has a very high phosphoryl group transfer potential because it exists in its unstable enol form ...
... • Elimination of water from C-2 and C-3 yields the enol-phosphate PEP • PEP has a very high phosphoryl group transfer potential because it exists in its unstable enol form ...
Enzymes
... Competitive inhibition • Competitive inhibitor „competes“ with a substrate S for binding at enzyme´s active site. • It is bound to an active site but not converted by the enzyme. • Vmax value is unchanged. • KM value is elevated (it is necessary to add more S to reach the original enzyme activity) ...
... Competitive inhibition • Competitive inhibitor „competes“ with a substrate S for binding at enzyme´s active site. • It is bound to an active site but not converted by the enzyme. • Vmax value is unchanged. • KM value is elevated (it is necessary to add more S to reach the original enzyme activity) ...
Activin Receptor IIB human (A9579) - Datasheet - Sigma
... 3. Sporn, M.B., and Roberts, A.B., eds. Peptide Growth Factors and Their Receptors, SpringerVerlang Heidelberg, Vol. II, pp 217-235 (1991). 4. De Jong, F., et al., Effects of factors from ovarian follicular fluid and Sertoli cell culture medium on invivo and in-vitro release of pituitary gonadotroph ...
... 3. Sporn, M.B., and Roberts, A.B., eds. Peptide Growth Factors and Their Receptors, SpringerVerlang Heidelberg, Vol. II, pp 217-235 (1991). 4. De Jong, F., et al., Effects of factors from ovarian follicular fluid and Sertoli cell culture medium on invivo and in-vitro release of pituitary gonadotroph ...
ppt
... • Describe basic steps for synthesis of fatty acids from dietary glucose (or amino acids) in the liver • Explain the role of VLDL lipoprotein particles • Explain the use of fatty acids for triglyceride ...
... • Describe basic steps for synthesis of fatty acids from dietary glucose (or amino acids) in the liver • Explain the role of VLDL lipoprotein particles • Explain the use of fatty acids for triglyceride ...
Ch. 33 Synthesis of Fatty acids, Triacylglycerols, Membrane lipids
... • Receptors for viruses Ceramide is central molecule • Serine basis • Fatty acid addition, release CO2 • Reduction • Other fatty acid to NH2 group • Oxidation ...
... • Receptors for viruses Ceramide is central molecule • Serine basis • Fatty acid addition, release CO2 • Reduction • Other fatty acid to NH2 group • Oxidation ...
Protein and Amino Acids
... Protein Bioavailability Why do substrates have different protein digestibilities? Different amino acid profiles Different amounts of CP ...
... Protein Bioavailability Why do substrates have different protein digestibilities? Different amino acid profiles Different amounts of CP ...
Oxytocin Hormone synthesis and regulation in the Body
... the cytosol, which carry the bioregulator inside the target cell (page 53, book). The GPCR once activated interact with others G proteins such as Gs protein, Gi protein or Gq protein. The interaction between these G proteins causes the activation of different second messenger such as cAMP for t ...
... the cytosol, which carry the bioregulator inside the target cell (page 53, book). The GPCR once activated interact with others G proteins such as Gs protein, Gi protein or Gq protein. The interaction between these G proteins causes the activation of different second messenger such as cAMP for t ...
COPYRIGHTED MATERIAL
... awareness of the existence of metabolic pools is essential to an understanding of human metabolism. For example, one might expect that a fasted individual would show a fall in all essential nutrient levels in the plasma pool. In many instances this is not the case initially because of the existence ...
... awareness of the existence of metabolic pools is essential to an understanding of human metabolism. For example, one might expect that a fasted individual would show a fall in all essential nutrient levels in the plasma pool. In many instances this is not the case initially because of the existence ...
Lipid signaling
Lipid signaling, broadly defined, refers to any biological signaling event involving a lipid messenger that binds a protein target, such as a receptor, kinase or phosphatase, which in turn mediate the effects of these lipids on specific cellular responses. Lipid signaling is thought to be qualitatively different from other classical signaling paradigms (such as monoamine neurotransmission) because lipids can freely diffuse through membranes (see osmosis.) One consequence of this is that lipid messengers cannot be stored in vesicles prior to release and so are often biosynthesized ""on demand"" at their intended site of action. As such, many lipid signaling molecules cannot circulate freely in solution but, rather, exist bound to special carrier proteins in serum.