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Organism In biology, an organism is any contiguous living system (such as animal, plant, fungus, or micro-organism). In at least some form, all organisms are capable of response to stimuli, reproduction, growth and development, and maintenance of homoeostasis as a stable whole. An organism may either be unicellular (single-celled) or be composed of, as in humans, many trillions of cells grouped into specialized tissues and organs. The term multicellular (many-celled) describes any organism made up of more than one cell.