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Review sheet – Chapter 4 Know that Robert Hooke was the first person to describe cells with a microscope and that Antoni van Leeuwenhoek was the first person to describe/see bacteria Be able to describe the cell theory Understand that the electron microscope provides greater resolution than a traditional light microscope and allowed for scientists to examine the internal anatomy of cells Know that some cells can be large (up to 1m) but most are microscopic Know that cells are limited in size by the internal molecules and structures necessary for survival (minimum size) and by the surface area/volume relationship (as you get bigger, your SA/V decreases) needed to obtain nutrients and exchange gases with the environment Understand that prokaryotic cells are small (1-10µm) while eukaryotic cells are somewhat larger (10-100µm) Understand that a larger cell has more surface area and more volume than a smaller cell, but that the surface area/volume ratio of a larger cell is less than that of a smaller cell Know the difference between eukaryotic cell and prokaryotic cells in terms of size, internal structure and DNA storage Understand that all cells – prokaryotic or eukaryotic – are bounded by a plasma membrane, have chromosomes made of DNA, and contain ribosomes Understand the four basic functional groups of organelles (manufacturing, hydrolysis, energy processing, and support/movement/communication) and which organelles belong to which Understand the differences between plant and animal cells (chloroplasts, cell walls, central vacuole = plant) Know what cytoplasm is Understand the function and structure of the plasma membrane; understand that proteins form channels enabling specific ions and other molecules to cross Understand that the nucleus contains most of the cell’s DNA (where is the rest?) and controls the cell’s activities by directing protein synthesis Know what chromatin is and be familiar with its ‘beads-on-a-string’ structure Understand that the nucleolus is the site where ribosomal RNA (rRNA) is synthesized and that rRNA assembles proteins to form ribosomes Know what each organelle’s function is in the cell (ribosomes, smooth and rough ER, Golgi apparatus, lysosomes, vacuoles, mitochondria, the cytoskeleton, and the extracellular matrix) Know the difference (structure and function) between rough and smooth ER Understand that organelles are membrane-bound and the significance of this Be familiar with the 3 different types of vacuoles Understand the process of cellular respiration (by definition; we go more into this in Chapter 6) Understand that mitochrondria and chloroplasts provide evidence for endosymbiosis (how?) Know the 3 types of filaments: microfilaments, microtubules, and intermediate, and how they differ by size Know the difference between cilia and flagella and that they are made up of microtubules in a “9+2” arrangement Know what a gap junction is