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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 B.Sc. DEGREE EXAMINATION – ADVANCED ZOOLOGY & BIOTECH. FIFTH SEMESTER – NOVEMBER 2011 AZ 5513 - GENETICS Date : 04-11-2011 Time : 9:00 - 12:00 Dept. No. Max. : 100 Marks PART-A Answer ALL the questions (10x2=20) 1. Define Linkage map. 2. What is Codominance? Give an example. 3. Distinguish between Cistron and Muton 4. Name the enzymes involved in DNA replication. 5. What is Inbreeding Depression? 6. List the factors that affect gene frequencies. 7. Mention any two applications of pedigree analysis. 8. What are transposons? 9. Give any two examples for sex chromosomal anomalies. 10. Comment on Gene Therapy. PART-B Answer any FOUR of the following (4x10=40) 11. Define Epistasis. Explain the Dominant Epistasis with a suitable example. 12. Explain the mode of inheritance of red green colour blindness in man. 13. Describe the structure and functions of different types of RNA. 14. Briefly discuss the role of plasmids and restriction enzymes in Genetic Engineering. 15. With neat labelled diagrams explain the Lytic Cycle of bacteriophages. 16. Illustrate the Phenylalanine metabolic pathway and add a note on the characteristic features of various metabolic disorders associated with it. PART-C Answer any TWO of the following (2x20=40) 17. Define Multiple allelism. Explain the same with reference to ABO blood groups in human. Add a note on the significance of Rh antigen. 18. Describe in detail the three different modes of Genetic Recombination in Bacteria. 19. Give an account on Genetic Counselling and planned genotypes. 20. State the differences between Cytoplasmic Inheritance and Nuclear Inheritance. Give any three examples for Cytoplasmic Inheritance. $$$$$$$