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1 External and Internal Respirations The process by which Oxygen and Carbon dioxide diffuse in and out of the blood is respiration. Respiration occurs in two areas of the body and is also referred to as gas exchange. The gas exchange across the respiratory membrane in the lungs is known as External respiration while gas exchange across the respiratory membrane in the metabolizing tissues is known as the Internal respiration. In external respiration, the exchange of gases takes place between the alveoli and lung capillaries. Oxygen is distributed into the blood from the alveoli and Carbon dioxide moves from the blood in the alveoli. While in internal respiration the exchange of gases is only in body tissues. Gas exchange in the lungs is called as external respiration as the alveolar air is outside of the body. As blood flows through the pulmonary capillaries, Oxygen diffuses into the blood and Carbon dioxide diffuses into the alveolar gas. Both the gases diffuse down their own partial pressure gradient and equilibrate. Oxygen -rich blood will then be delivered to the tissues. The gases move in opposite directions in internal respiration compared to external respiration. Oxygen is diffused out of the blood into the tissues and Carbon dioxide is diffused out of the tissues into the blood. In external respiration, air is drawn into the body to supply Oxygen to the lungs and air is expelled from the lungs to remove Carbon dioxide from the body. In internal respiration, the gases in the air which is already inhaled in the lungs by external respiration are exchanged with gases in the tissues. As a result of internal respiration, Carbon dioxide is removed from the blood and is replaced with Oxygen. 2 Reference External and Internal Respiration in the Lungs: Definition & Process. In Education Portal. Retrieved on March 27, 2014 from http://education-portal.com/academy/lesson/externaland-internal-respiration-in-the-lungs-definition-process.html#lesson