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Transcript
Endocrine control of osmolarity Antidiuretic hormone (ADH) Aldosterone Atrial natriuretic peptide (ANP) Osmoregulation: ADH • • • • Induces H2O conservation Released from posterior pituitary Peptide hormone Activates kidney cells to increase water pores on membrane surface inside collecting duct • Net effect: water conservation Figure 45.6a Hormones of the hypothalamus and pituitary glands Osmoregulation: Vasopressin (ADH) Osmoregulation: Aldosterone • Induces Na+ conservation • Synthesized and released from adrenal cortex • Steroid hormone (moves in and out of cells by diffusion) • Acts on kidney cells to increase production of Na+ membrane channels and Na+/K+ pumps Osmoregulation: Aldosterone Osmoreg.:Atrial natriuretic peptide • Induces Na+ and water excretion • Released from the heart when plasma volume is high • Peptide hormone • Acts on the kidney to increase Na+ & water excretion, mechanisms not well understood • Also act as antagonist to vasopressin and aldosterone Aldosterone & ADH effects on OsM • If aldosterone rises OsM increases or decreases? • If ADH rises OsM increases or decreases? Endocrine control of basal metabolic rate - thyroxine and triiodothyronine Figure 45.6b Hormones of the hypothalamus and pituitary glands Thyroid hormones - amines from thyroid that regulate BMR Thyroid hormone control and function Hypothalamus Anterior pituitary Thyroid glands Indicate whether level is increased, decreased or no change Primary thyroid tumor hypersecreting hypothalamus anterior pituitary thyroid gland TRH Secondary hypothalamic atrophy due to local stroke TRH Iodine deficiency TRH TSH TSH TSH T3 & thyroxine T3 & thyroxine T3 & thyroxine metabolic rate metabolic rate metabolic rate Endocrine response to stress - epinephrine and norepinephrine - cortisol Figure 45.14 Stress and the adrenal gland Catecholamine hormones - amines that control our response to acute stress - Cardiac output increases - Blood vessels to skel. muscles dilate - Blood vessels to dig. organs constrict - Liver produces glucose Cortisol control Diurnal rhythm & chronic stress hypothalamus CRH (+) anterior pituitary ACTH negative feedback (-) (+) adrenal cortex cortisol catabolic effects Break down proteins and fats to make more plasma glucose