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Neuronal adaptation
Jagat Ramdin
Neuromorpho.org
• Neuromorpho.org is a regularly updated
online database of neurons of many species
and brain reasons.
• Because it is free to access, if one wishes to
take data or images, it can easily be done.
Acquiring the Data
• The goal of this exercise was to consolidate data
on the most commonly gathered brain regions
from humans. Only pyramidal neurons were
examined.
• The regions chosen were the top four found:
• 1) Prefrontal Cortex -392 entries
• 2) Parietal Lobe -100 entries
• 3)Anterior Cingulate -20 entries
• 4) Fronto-Insula -16 entries
• Total entries: 528 neurons
Data analysis
• Using WEKA, through a combination of
different classification programs, the following
was generated:
Histograms
• The next slides will show histograms based on
the 20 attributes recorded by the
experimenters who submitted these neurons
• There was very little variation in these
histograms. Despite the dark blue, prefrontal
cortex data being the most abundant, there is no
outstanding attributes to any of these 4 brain
region’s pyramidal neurons.
• It should be noted that some of the Anterior
Cingulate neurons were the most prevalent in
terms of outliers when the category referenced
length or size.
• More data from this region is necessary to make
claim, however.
Clusters based on 20 attributes
• The circles and black lines were done via
paint.
• This was purely to illustrate the groups for the
audience and highlight the lack of clusters for
group 2.
• X axis is the actual group while Y axis is the
predicted group from a classifier.
• The previous graph shows that prefrontal and
parietal lobe neurons are near
indistinguishable. While it appears unhelpful,
it emphasizes just how much the frontal and
parietal lobes communicate. The prefrontal
cortex is responsible for high end cognitive
functions while the parietal lobe collates
information from different sensory systems;
touch, sight, etc.
• While the blue and red near the front of the
brain, the green and light blue are deeper in.
These two brain areas rarely clashed with the
blue and red areas in terms of being misclassified
together.
• This suggests that it isn’t function that causes
neurons to differentiate, but its neighbors who it
connects to instead.
• That being said, there is far too little on the green
and light blue regions to make any affirmative
statement.
Future research
• Rather than humans, use of primate or rats
with humans to determine if empirical data is
proportional to substitute for humans.
• Waiting for or performing research in other
brain areas to gather more data on neurons
that are not researched as often.