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Introduction BIO 411 Medical Microbiology The Prophet’s View of Education • “You are all in school. Do not waste your time. This is a time of great opportunity that you will never have again as long as you live. Make the most of it right now…. • “…you can’t afford to waste your time. There is so much to learn. Give it the very best that you have.” – Gordon B. Hinckley Syllabus • So what are we going to learn about this semester? • Syllabus • What does it take to succeed in Bro. Wray’s class? • First Assignment – Elder Eyring Article Medical Microbiology Chapter 1 Intro. to Medical Microbiology Intro. to Medical Microbiology • History of Microbiology – Anton van Leeuwenhoek (1674) – Friedrich Henle (1840) – Germ Theory of Disease – Robert Koch and Louis Pasteur (late 1800’s) – Alexander Fleming (1928) - Penicillin Intro. to Medical Microbiology • Groups of Microorganisms – Viruses • • • • • • DNA or RNA genome Protein coat (capsid) Some have a membrane envelope Obligate intracellular parasites Pathogenesis Diseases? Intro. to Medical Microbiology – Bacteria • • • • • • Prokaryotic organisms Peptidoglycan cell wall Gram + and Gram – Cell shapes and arrangements Pathogenesis - toxins Diseases? Intro. to Medical Microbiology – Fungi • Eukaryotic • Yeasts, molds, dimorphic fungi • Diseases? – Parasites Intro. to Medical Microbiology • Microbial Disease – Most organisms don’t cause a single disease • Staphylococcus aureus, meningitis, etc. – Few microbes are always pathogenic – Exogenous infections vs. endogenous infections • Normal Flora