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Percutaneous Cryoablation for Renal Cell
Cancer
• Christos Georgiades MD PhD
• Assistant Professor of Radiology & Surgery
• Vascular & Interventional Radiology
• Johns Hopkins Hospital
Stamping Out Kidney Cancer Without
Surgery
• 55,000 patients are diagnosed with kidney
cancer every year in the US…and increasing
08
20
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03
20
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00
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20
50
19
• 75% of them are
discovered by accident
and most small enough
to be treated by
Interventional
Radiology (Avoid
Surgery)
60000
50000
40000
30000
20000
10000
0
How is Cryoablation done?
Skin
Tumor
1. No incision/No surgery
2. No general anesthesia
Kidney
Needle
3. Ablation needle(s) placed
by Interventional
Radiologist under Image
guidance
Our Experience
– Treated 90 tumors (in 84 patients)
2006-2008
– 80 under sedation
– 4 local anesthesia only
– Never general anesthesia
– Ages 35-90
– Follow up every 3 months up to a year and
then annually
Results
-Of the 90 tumors (1-10 centimeters)
• 88 completely treated without any evidence for
cancer (98%)
• 2 had small tumor left (~1cm), one retreated
with ablation and now no tumor left (99%)
• No patients developed new local cancer or
metastatic cancer after ablation and none
required surgery
Tumor
1-Year
2-Years
3-Years
Summary
• Cryoablation by Interventional Radiology has a near
100% success rate in treating kidney cancers up to 4
and probably up to 7 centimeters in size
• No incision/no surgery/no anesthesia
• Most patients go home same day and can resume
normal activities quickly
• Fewer complications, lesser cost
• In the unlikely case cryoablation fails, patients can still
have the surgery they would have in the first place.
Conclusions
• Cryo-ablation should be the first treatment
choice for patients whose kidney cancer is 4
centimeters or smaller.
and
• If a patient wishes to avoid or cannot have
surgery, even larger lesions can be treated (near
100% success rate cancer up to 7 centimeters in
size)