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Transcript
Mutations Definition • A mutation is a change in an organism’s DNA – Silent mutations are changes that do not result in a change to the organisms phenotype – Mutations that occur in germ cells (sperm, eggs) are passed on to offspring – Mutations in somatic (body) cells may be harmless, or may result in disease such as cancer Chromosomal Mutations A Point Mutation Resulting in Nonsense A Point Mutation: An Analogy the red dog bit the tan cat the red mog bit the tan cat This point mutation changes the meaning, resulting in nonsense A Point Mutation Resulting in Missense A Point Mutation: An Analogy the red dog bit the tan cat the red hog bit the tan cat This point mutation changes the meaning, resulting in missense An Insertion Mutation in a Gene An Insertion Mutation: An Analogy the red dog bit the tan cat the red rdo gbi tth eta nca This insertion mutation changes the reading frame A Deletion Mutation in a Gene An Deletion Mutation: An Analogy the red dog bit the tan cat the red ogb itt het anc at_ This deletion mutation changes the reading frame A Frameshift Mutation
