Download Cell Metabolism - Buffalo State College Faculty and Staff

Cell Metabolism
Mader Chapter 3.3
Organismal
vs. cellular
respiration
Enzymes are proteins that
catalyze chemical reactions in
cells.
Enzymes combine temporarily with specific substrates to facilitate
a reaction and they are released at the end of the reaction, unchanged.
The mitochondrion – site of
oxidative metabolism
Oxidation of glucose
Matrix
Inner
Memb.
6
2
2
NAD+ 2e-  NADH2
2 + 2 + 34 = 38 ATP
34
Exercise (aerobic & anaerobic)
Anerobic – fermentation of
glucose (0xygen debit)
O2
LIVER
MUSCLE
H2O
CO2
Glucose
Blood
When muscle operates
anaerobically, glycolysis
generates NADH2
NAD is regenerated by
putting the H2 on pyruvic
acid making lactic acid.
When oxygen becomes
available, lactic acid is
converted to pyruvic acid in
the liver. The puruvic acid is
metbolized to CO2 & H20 and
ATP is generated