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CATARACT SURGERY AND GENITOURINARY MEDICATIONS Frank J. Weinstock, MD, FACS When you have any surgery performed it is essential that you tell your surgeon all of the medications that you take since many may interfere with your surgery, such as causing bleeding, untoward reactions to anesthesia etc. One of the main concerns is the group of men who have BPH (benign prostatic hypertrophy) and are given Flomax (tamsulosin). Because of extensive advertising of Flomax, it is often assumed that it is totally safe (warnings are mentioned if you pay attention). However, when undergoing cataract surgery, patients using Flomax have a significantly high number of complications than those who do not use it. In an article by David Chang, MD, it is mentioned that the risk of severe postoperative complications such as retinal detachment is 2.3 tunes the incidence of other patients who do not use the medication. What happens is that the iris (the colored portion of the eye around the pupil) becomes “floppy” in some of these patients This is called the IFIS or floppy iris syndrome. Since, in cataract surgery, it is necessary to dilate or enlarge the pupil in order to perform the surgery, inability to dilate the pupil may lead to major complications. Although well know to most ophthalmologists, primary care physicians are often not familiar with this. Therefore, it is essential that your ophthalmologist and primary care physician know about these medications beforehand. In one of Dr. Chang’s studies, the “floppy iris syndrome” showed up in patients in up to 2 years after stopping Flomax. In one study by ASCRS (The American Society of Cataract and Refractive Surgery), 95% of surgeons felt that tamsulosin made cataract surgery more difficult and 77% felt that the risks of complications were greater. 95% would try to avoid it for themselves if they had cataracts. What can the patient do? First, be sure to notify your ophthalmologist that you are using tamsulosin (Flomax). Ask your surgeon if he or she feels comfortable doing the cataract surgery. Recognize that most ophthalmologists have experience dealing with this meaning that they can usually avoid surgical complications and rarely have problems if they know about Flomax prior to surgery. If you have cataracts and require medications for BPH, discuss this with your physician and you may want to ask him or her to consider other medications since the other medications available do not seem to cause a problem, especially if you have not used Flomax beforehand. It might be a good idea for your primary care physician or urologist to communicate with your ophthalmologist about this. Frank J. Weinstock, MD, FACS Boca Pointe- Canton, Ohio Professor of Ophthalmology- NEOUCOM Affiliate Clinical Professor in The Charles E. Schmidt College of Biomedical Science at Florida Atlantic University, Boca Raton. Volunteer Professor of Ophthalmology – The University of Miami Leonard M. Miller School of Medicine