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Lactanase
®
Supplies nutrients important for the formation of acetyl coenzyme A, the gateway to efficient release of cellular
energy
• Special combination of riboflavin, pantothenic acid, thiamine, niacin and lipoic acid
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Helps cells efficiently deliver fuel from anaerobic metabolism to the Krebs cycle for energy release
Contains the key nutrients needed to release energy from both carbohydrates and fats
A favorite of Thoroughbred and Standardbred trainers and veterinarians
Easily absorbed, so it can be given shortly before performance for extra metabolic power
What Is Lactanase? Lactanase supplies nutrients important for the formation of acetyl coenzyme A in the horse's body.
Acetyl coenzyme A is the gateway to the Krebs cycle, where the release of cellular energy takes place. This formula was the
first pre-performance supplement to focus on the need for acetyl coenzyme A during intensive exercise, when the horse
cannot rely upon oxygen for energy release. Lactanase has been tested by Thoroughbred and Standardbred trainers and
veterinarians at the nation's leading racetracks. It is now available to all horsemen for optimum support of horses involved in
intensive exercise and performance.
Anaerobic Metabolism is Used To Maintain Intensive Exercise When horses perform or exercise intensely, they quickly
face a demand for energy that is greater than the amount of oxygen available to produce it. When more than half of the
horse's energy is produced without oxygen, the horse is performing anaerobically. Anaerobic metabolism typically begins to
dominate after galloping only one-quarter of a mile, and for many horses it kicks in sooner. Lactanase addresses some of the
fundamental nutritional needs of anaerobic metabolism to provide targeted support for high-intensity equine athletes.
The Bridge to ATP D-Glycogen is the main energy source for intensive exercise that lasts more than a few seconds. It is
converted through many steps to enter the Krebs cycle to produce ATP, the basic biological energy source. In the anaerobic
metabolism of intense exercise, these steps must be made without additional oxygen. A crucial junction is the conversion of
pyruvate (from glycogen) to acetyl coenzyme A, where it enters the Krebs cycle. If the cell lacks the necessary nutrients to
form acetyl coenzyme A, pyruvate will be changed into lactic acid (lactate). Lactic acid must be reconverted or transported to
the liver for processing through the Cori cycle. Researchers point to the buildup of lactic acid in the blood and within the
muscle cells as a possible indication of fatigue and inability of the cells to produce energy and control muscle function.
The Essential Co-Factors And The Lactanase Formula Lactanase supplies nutrients that serve as substrates of key
enzymes needed for the conversion of pyruvate to acetyl coenzyme A. Thiamine, also known as vitamin B1, forms thiamine
pyrophosphate, or TPP, a coenzyme used to begin pyruvate conversion. Lipoic acid is a sulfur-bearing fatty acid that is
produced within the body, and is also found in low levels in yeast, liver and other foods. Lipoic acid's unique arrangement of
electrons gives it a key role in the synthesis of acetyl coenzyme A. Pantothenic acid, sometimes called vitamin B5, is a major
building block of acetyl coenzyme A. Riboflavin, or B2, is the basis of an enzyme called FAD, and niacinamide (a form of
vitamin B3) is used to produce NAD, a coenzyme. These are the nutrients supplied by Lactanase. Together they help the cells
to efficiently deliver fuel from anaerobic metabolism to the Krebs cycle for energy release. Because the horse can quickly and
easily absorb these nutrients, Lactanase can be given shortly before performance to provide extra metabolic power when you
really need it.
Bonus: Lactanase And The Metabolism Of Fats One of the main pathways to release energy from fats produces a fatty
acid called alpha-ketoglutarate. Like pyruvate, alpha-ketoglutarate must cross a crucial bridge before it can be used in the
Krebs cycle. Thiamine, lipoic acid, pantothenic acid and niacinamide support the enzymes that get the job done. Lactanase
does double duty with key nutrients the horse needs to release energy from both carbohydrates and fats.
Feeding Instructions: Blend thoroughly with feed. For support under stressful conditions, feed one packet daily for two days.
Thereafter feed one-half to one packet as needed. For performance support, feed one packet 2 to 3 hours prior to
performance. For maximum support, feed one additional packet the evening before performance.
© 2005 Vita Flex Nutrition