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Product Monograph for Herbal Magic
Chewable Multi
NPN 80056032
GENERAL INFORMATION
Herbal Magic’s Chewable Multi is a great tasting chewable multivitamin/mineral tablet which contains a blend of vitamins and
minerals formulated to help meet the nutritional needs of those
aged 12 and over. Vitamins by definition are dietary substances
required for good health and normal development. Their functions
can be quite complex wherein any particular vitamin may have
various metabolic and chemical roles. Minerals, like vitamins, act
as co-enzymes enabling the body to perform its functions including
energy production, growth and healing. This formulation is useful
for those who have difficulty swallowing tablets or capsules.
Chewable Multi is a fundamental comprehensive multivitamin/mineral designed to fill potential nutritional gaps and
support successful weight management.
This daily multivitamin helps to:

Ensure the body is functioning optimally

Promote efficient metabolism by breaking down food and
ensuring optimal thyroid function

Ensure optimal intake of nutrients to prevent nutritional
deficiencies

Support healthy skin
RECOMMENDED USES

Primary Uses: helps maintain good health; helps in the
metabolism of carbohydrates, fats and proteins; helps normal
growth and development.

Secondary Use: Supports healthy skin.
MECHANISM OF ACTION
Research Suggests
Biotin
Biotin is a water-soluble vitamin that plays an essential role in
maintaining metabolic homeostasis. Biotin acts as a cofactor in
gluconeogenesis, fatty acid synthesis and amino acid catabolism.
1,2,3
Copper
Copper is an essential trace metal that plays an integral part in
numerous critical enzyme processes affecting vital biological
systems. Copper helps to produce and repair connective tissue,
and aids in formation of red blood cells. 4,5
Iron
Iron is a vital trace mineral that participates in a wide variety of
metabolic processes, including oxygen transport, DNA synthesis,
and electron transport. Iron concentrations in the body are tightly
regulated. 6,7 Low iron stores can lead to fatigue, weakness,
decreased energy, loss of appetite and impaired cognitive
functioning.8
Magnesium
Magnesium is critical to normal human homeostasis playing many
roles in energy metabolism: as an enzyme cofactor, in electrolyte
balance, and in the maintenance of the properties of various cell
membranes. As one of the four most abundant cations in the
body, magnesium is present in more than 300 enzymatic systems.
9,10
Magnesium helps the body to metabolize carbohydrates, fats
and proteins. Magnesium also plays an important role in
maintaining muscle function and in the absorption of calcium. 10,11
Niacinamide
Niacinamide is an essential organic compound for metabolism,
essential for energy production from carbohydrates, fatty acids,
and amino acids.12 Niacinamide is necessary for a variety of
diverse biological processes including energy production and acts
as an antioxidant.13
Pantothenic acid
Pantothenic acid is involved in the metabolism of carbohydrates,
proteins and lipids and is a component of coenzyme A, a molecule
necessary for many vital chemical reactions to occur in cells.14,15
Riboflavin
Riboflavin is a water-soluble vitamin, important for human
metabolism, protecting against cancer and cardiovascular disease.
The body requires more riboflavin in cases of increased metabolic
demand such as during weight loss or in periods of high stress. In
such cases, the supply may be rapidly depleted so it is important
to ensure frequent and sufficient replenishing of this essential
vitamin. 16,17
Thiamine
Thiamine is a water-soluble vitamin, essential in metabolic energy
production and the metabolism of fats, carbohydrates and
proteins. As humans are unable to synthesize thiamine, this
vitamin must be obtained exogenously. The body requires more
thiamine in cases of increased metabolic demand such as during
weight loss. In such cases, the supply may be rapidly depleted so
it is important to ensure frequent and adequate supply of this
essential vitamin. 18,19
Vitamin A
Vitamin A has several functions in the body, including supporting
healthy growth, repair and maintenance of epithelial cells, bone
and tooth development, and a healthy immune system. Vitamin A
is also critical in the maintenance of healthy vision. Due to
deficiency in the diet, or lack of variety in the diet, many may be
missing important nutrients for maintaining eye health. Vitamin A
supports the healthy surface linings of the eyes, without which the
eyes could become susceptible to infection. Additionally, a
deficiency in vitamin A could lead to night blindness. 20
Vitamin B6
Vitamin B6 acts as cofactor in more than 140 different enzyme
reactions and has critical functions in cellular metabolism and
stress responses. It is a potent antioxidant that effectively
quenches reactive oxygen species and is thus of high importance
for cellular health. 21,22,23
Vitamin B12
Vitamin B12 aids in the formation and regeneration of red blood
cells, thereby preventing anemia. Vitamin B12 promotes growth
and is essential for the maintenance of a healthy nervous system.
Vitamin B12 supports normal DNA synthesis, promotes growth24,
and also assists in the proper utilization of fats, carbohydrates and
proteins.18,25
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Vitamin C
Humans are unable to synthesize vitamin C and therefore must
obtain this vitamin exogenously. Vitamin C works as an antioxidant
in the body and is one of the most important vitamins responsible
for collagen, carnitine and neurotransmitter biosynthesis. 26,27,28 As
an antioxidant, vitamin C can help to limit the damaging effects of
free radicals29 which can compromise the vital health of cells and
can lead to the onset of various chronic conditions.30,31
Vitamin D
Vitamin D is a fat-soluble vitamin that plays a pivotal role in
maintaining health.32 Vitamin D assists the absorption of calcium
and phosphorus in the intestines and is important during periods
of growth as it plays a critical role in bone mineralization.33,34 While
the majority of individuals may be deficient in Vitamin D, several
groups are at high risk for vitamin D deficiency, including
overweight individuals.35,36 Supplementation in these groups is,
therefore, especially important. A healthy diet with adequate
calcium and vitamin D, and regular physical activity, helps to
achieve strong bones.37
Vitamin E
Vitamin E is a fat-soluble vitamin, best known for its major
function as an antioxidant that prevents the formation of free
radicals and repairs free radical cell damage.38
Zinc
Zinc is an essential co-factor in a variety of cellular processes
affecting reproduction, bone formation, growth, and wound
healing. Zinc has been purported to play an important role in
normal thyroid homeostasis. 39,40,41
RECOMMENDED DOSAGE
For Ages 12+: 1 chewable tab 2x/day with meals, a few hours
before or after other medications.
CAUTIONS AND WARNINGS
No Statement.
DISEASE/CONDITION INTERACTIONS
No Statement.
DRUG INTERATIONS
No Statement.
To prevent any interactions, all Herbal Magic centres offer our
unique Medication Cross-Reference System, designed to provide
evidence-based safe dosing options for Herbal Magic products
such as Chewable Multi with other medications that the client is
taking.
FORMULATION
Medicinal Ingredients per chewable:
Biotin ............................................................................. 5 mcg
Copper (Cupric citrate) .................................................. 500 mcg
Iron (Ferrous fumarate) ..................................................... 5 mg
Magnesium (Magnesium oxide) ......................................... 10 mg
Niacinamide ...................................................................... 5 mg
Pantothenic acid (Calcium-D-pantothenate) ..................... 2.5 mcg
Riboflavin ....................................................................... 2.5 mg
Thiamine (Thiamine mononitrate) .................................... 2.5 mg
Vitamin A (All-trans retinyl palmitate) ………. 700 mcg RAE/2316 IU
Vitamin B6 (Pyridoxine hydrochloride) ................................. 1 mg
Vitamin B12 (Cyanocobalamin) .......................................... 2 mcg
Vitamin C (Ascorbic acid) .................................................. 50 mg
Vitamin D (Cholecalciferol) ................................ 2.5 mcg / 100 IU
Vitamin E (dl-α-Tocopheryl acetate) …................. 1.4 mg AT/ 3 IU
Zinc (Zinc sulfate) ........................................................... 0.5 mg
Non-medicinal Ingredients:
Sucrose, stearic acid, natural fruit flavor, citric acid, turmeric,
magnesium stearate, silica, beetroot red.
Features:

Gluten Free

Dairy Free

Only natural colours and flavours are included.
For further information, please contact the Herbal Magic
Scientific Advisory Team at 1-866-787-0050.
REFERENCES
1 Zempleni J, Wijeratne SS, Hassan YI. Biotin. Biofactors.
2009;35(1):36-46.
2 Health Canada. Natural Health Products Directorate. Product
Monographs. Biotin. 2007. Available at: http://webprod.hcsc.gc.ca/nhpid-bdipsn/monoReq.do?id=41&lang=eng.
Accessed May 21, 2015.
3 Gravel RA, Narang MA. Molecular genetics of biotin metabolism:
old vitamin, new science. J Nutr Biochem. 2005;16(7):428-31.
4 Health Canada. Natural Health Products Directorate. Product
Monographs. Copper. 2007. Available at: www.hc-sc.gc.ca
Accessed May 21, 2015.
5 Gaetke L.M, Chow CK. Copper toxicity, oxidative stress, and
antioxidant nutrients, Toxicology. 2003;189(1-2):147-63.
6 Lieu PT, Heiskala M, Peterson PA, et al. The roles of iron in
health and disease. Mol Aspects Med. 2001;22(1-2):1-87.
7 Nadadur SS, Srirama K, Mudipalli A. Iron transport &
homeostasis mechanisms: their role in health & disease.
Indian J Med Res. 2008;128(4):533-44.
8 National Institutes of Health. Dietary Supplement Fact Sheet:
Iron. http://ods.od.nih.gov/factsheets/IronHealthProfessional.
9 Health Canada. Natural Health Products Directorate. Product
Monographs. Magnesium. 2007. Available at: www.hc-sc.gc.ca
Accessed May 21, 2015.
10 Fox C, Ramsoomair D, Carter C. Magnesium: Its Proven and
Potential Clinical Significance. South Med J. 2001;94(12):1195201.
11 Health Canada. Natural Health Products Directorate. Product
Monographs. Magnesium. 2007. Available at:
http://webprod.hc-sc.gc.ca/nhpidbdipsn/monoReq.do?id=135&lang=eng. Accessed May 21,
2015.
12 Health Canada. Natural Health Products Directorate. Product
Monographs. Niacinamide 2009. Available at
http://webprod.hc-sc.gc.ca/nhpidbdipsn/monoReq.do?id=142&lang=eng. Accessed May 21,
2015.
13 Bogan KL, Brenner C. Nicotinic acid, nicotinamide, and
nicotinamide riboside: a molecular evaluation of NAD+
F OR PROFESSIONAL U SE O NLY
F OR P ROFESSIONALS TO RECEIVE A PRINTED COPY OF THIS MONOGRAPH , CONTACT HERBAL M AGIC CLINICAL
SUPPORT AT [email protected] OR 1-866-787-0050.
11/09/15 Rev 0
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precursor vitamins in human nutrition. Annu Rev Nutr.
2008;28:115-30.
14 Picciano MF, Pregnancy and lactation: physiological
adjustments, nutritional requirements and the role of dietary
supplements. J. Nutr. 2003;133(6): 1997S-2002S.
31 Shils M.E., Olson J.A., Shike M., Ross A.C., editors. (2006).
Modern Nutrition in Health and Disease, 10th edition.
Lippincott Williams and Wilkins
32 Planton J, Meyer JO, Edlund BJ. Vitamin d. J Gerontol Nurs.
2011;37(1):9-13.
15 Health Canada. Natural Health Products Directorate. Product
Monographs. Pantothenic Acid 2007. Available at: www.hcsc.gc.ca Accessed May 21, 2015.
33 Health Canada. Natural Health Products Directorate. Product
Monographs.Vitamin D. 2007. Available at: www.hc-sc.gc.ca
Accessed May 21, 2015.
16 Powers HJ. Riboflavin (vitamin B-2) and health. Am J Clin Nutr.
2003;77(6):1352-60.
34 Rabovsky BA, Komarov AM, Ivie JS, Minimization of free radical
damage by metalcatalysis of multivitamin/multimineral
supplements. Nutrition Journal. 2010;9:61.
17 Woolf K, Manore MM. B-vitamins and exercise: does exercise
alter requirements? Int J Sport Nutr Exerc Metab. 2006;
16(5):453-84.
18 Gagnolf M, Czerniecki J, Radermecker M. Thiamine Status in
Humans and Content of Phosphorylated Thiamine Derivatives
in Biopsies and Cultured Cells. PLoS ONE. 2010;5:10, e13616.
19 Singleton CK, Martin PR. Molecular mechanisms of thiamine
utilization. Curr Mol Med. 2001;1(2):197-207.
20 National Institutes of Health: Office of Dietary Supplements.
Dietary Supplement Fact Sheet: Vitamin A and Carotenoids.
Available at: http://ods.od.nih.gov/factsheets/VitaminA
21 di Salvo ML, Contestabile R, Safo MK. Vitamin B(6) salvage
enzymes: Mechanism, structure and regulation. Biochim
Biophys Acta. 2010;[Epub ahead of print].
22 Mooney S, Leuendorf JE, Hendrickson C, et al. Vitamin B6: a
long known compound of surprising complexity. Molecules.
2009;14(1):329-51.
23 Health Canada. Natural Health Products Directorate. Product
Monographs. Pyroxidine-5-phosphate. 2007. Available at:
www.hc-sc.gc.ca. Accessed May 21, 2015.
24 Institute of Medicine (US) Standing Committee on the Scientific
Evaluation of Dietary Reference Intakes and its Panel on
Folate, Other B Vitamins, and Choline. Dietary Reference
Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate,
Vitamin B12, Pantothenic Acid, Biotin, and Choline.
Washington (DC): National Academies Press (US);
1998. Available from:
http://www.ncbi.nlm.nih.gov/books/NBK114310
35 Caan B, Neuhouser M, Aragak A, et al. Calcium Plus Vitamin D
Supplementation and the Risk of Postmenopausal Weight Gain.
Arch Intern Med. 2007;167(9):893-902.
36 De-Regil Luz, Palacios Cristina, Ansary Ali, et al. Vitamin D
supplementation for women during pregnancy. Cochrane
Database of Systematic Reviews, 2012;Issue 2.
37 L'Abbe MR, Whiting SJ, Hanley DA. The Canadian health claim
for calcium, vitamin D and osteoporosis. J Am Coll Nutr. 2004;
23:303-8.
38 Herrera E, Barbas C. Vitamin E: action, metabolism and
perspectives. J Physiol Biochem. 2001;57(1):43-56.)(
Mustacich DJ, Bruno RS, Traber MG. Vitamin E. Vitam Horm.
2007;76:1-21.
39 Ertek S, Cicero AF, Caglar O, Erdogan G. Relationship between
serum zinc levels, thyroid hormones and thyroid volume
following successful iodine supplementation. Hormones
(Athens). 2010;9(3):263-8.
40 Health Canada. Natural Health Products Directorate. Product
Monographs. Zinc. 2007. Available at: www.hc-sc.gc.ca.
Accessed May 21, 2015.
41 Barceloux DG. Zinc. J Toxicol Clin Toxicol. 1999;37(2):279-92.
25 Health Canada. Natural Health Products Directorate. Product
Monographs. Cyanocobalamin. 2007. Available at: www.hcsc.gc.ca. Accessed May 21, 2015.
26 Padayatty JS, Katz A. Vitamin C as an Antioxidant: Evaluation of
Its Role in Disease Prevention. J Am Coll Nutr. 2003;22(1):1835.
27 Carr AC, Frei B, Toward a new recommended dietary allowance
for vitamin C based on antioxidant and health effects in
human. Am J Clin Nutr. 1999;69:1086–107.
28 Health Canada. Natural Health Products Directorate. Product
Monographs. Vitamin C. 2007. Available at: www.hc-sc.gc.ca
Accessed Jan 4, 2011. 15 Planton J, Meyer JO, Edlund
29 National Institutes of Health. Dietary Supplement Fact Sheet:
Vitamin C. http://ods.od.nih.gov/factsheets/VitaminC-Health
Professional.
30 Groff J. & Gropper S. (2000). Advanced Nutrition and Human
Metabolism, 3rd edition. Wadsworth/ Thomson Learning.
F OR PROFESSIONAL U SE O NLY
F OR P ROFESSIONALS TO RECEIVE A PRINTED COPY OF THIS MONOGRAPH , CONTACT HERBAL M AGIC CLINICAL
SUPPORT AT [email protected] OR 1-866-787-0050.
11/09/15 Rev 0
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