Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Breast cancer The breast cancer research group work in association
Transcript
Professor Rob Sutherland AO FAA B Agr Sc, M Agr Sc (Hons), PhD, DSc (Hon.), FAA, FRACS (Hon.), AO Director, The Kinghorn Cancer Centre Petre Chair of Breast Cancer Research Head, Cancer Research Program, Garvan Institute of Medical Research NHMRC Senior Principal Research Fellow Conjoint Professor, Faculty of Medicine, UNSW Rob is the inaugural Director of The Kinghorn Cancer Centre. Rob’s vision to deliver a personalised medicine facility for cancer patients in Australia exemplifies the value that is gained from placing the patient at the centre of all decisions. Under his leadership, The Kinghorn Cancer Centre embraces a ‘Bedside to Bench’ approach to cancer research and cancer care, supporting the need for better diagnostic and treatment options for cancer patients. Rob also leads the prostate, breast and steroid hormone action research groups at The Kinghorn Cancer Centre. Group research: Breast cancer The breast cancer research group work in association with clinicians at several teaching hospitals in Sydney (St Vincent's, Royal Prince Alfred/Sydney Cancer Centre and St George) and major national and international trials groups (Australia New Zealand Breast Cancer Trials Group and International Breast Cancer Study Group). They have developed large tissue banks and patient databases that are being used to identify and validate new biomarkers of disease subtype, disease progression and response to particular therapies. These studies assist in the implementation of a biomarker-‐guided personal medicine approach to breast cancer treatment. A major joint project with the Cell Cycle, Apoptosis and Steroid Hormone Action Groups is identifying molecular markers of tamoxifen resistance, since loss of response to tamoxifen is a major reason for treatment failure. They are also conducting collaborative studies in-‐house and with other institutions to define the role of newly-‐discovered breast cancer genes in the disease process. Key words Breast cancer, biomarkers, disease progression, genomics, clinical research, drug resistance and therapeutic response parameters
