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Topographical distribution of bacteria on skin sites. The skin microbiome is highly dependent on the microenvironment of the sampled site. The family-level classification of bacteria colonizing an individual subject is shown with the phyla in bold. The sites selected were those that show a predilection for skin bacterial infections and are grouped as sebaceous or oily (blue circles); moist (typically skin creases; green circles); and dry, flat surfaces (red circles). The sebaceous sites are the glabella (between the eyebrows), alar crease (side of the nostril; external auditory canal [inside the ear]), retroauricular crease (behind the ear), occiput (back of the scalp), antecubital fossa (inner elbow), interdigital web space (between the middle and ring fingers), inguinal crease (side of the groin), gluteal crease (topmost part of the fold between the buttocks), popliteal fossa (behind the knee), plantar heel (bottom of the heel of the Source: Normal Human Microbiota, Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e foot), toe web space, and umbilicus (navel). Dry sites are the volar forearm (inside of the midforearm), hypothenar palm (palm of the hand proximal to the Carroll KC, Hobden JA, Miller S,from Morse SA, Mietzner TA, Detrick B, Mitchell TG, McKerrow JA. Jawetz, & little finger), Citation: and buttock. (Reprinted by permission Macmillan Publishers Ltd: Grice EA, Segre JA, The JH, skinSakanari microbiome. NatureMelnick, Rev Microbiol Adelberg’s Medical Microbiology, 27e; 2015 Available at: http://mhmedical.com/ Accessed: May 13, 2017 2011;9:244-253. Copyright © 2011.) Copyright © 2017 McGraw-Hill Education. All rights reserved