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Transcript
Stages in the early development of the spinal cord. A. The neural plate is generated from ectodermal cells that overlie the notochord (N) and the future
somites (S). It is flanked by the epidermal ectoderm.
B. The neural plate folds dorsally at its midline to form the neural fold. Floor plate cells (blue) differentiate at the ventral midline of the neural tube.
C. The neural tube forms by fusion of the dorsal tips of the neural folds. Roof plate cells form at the dorsal midline of the neural tube. Neural crest cells
migrate from the neural tube into and past the somites before populating the sensory and sympathetic ganglia.
Source:of
Patterning
System,
Principles
of Neuralpositions
Science,in
Fifth
D. Distinct classes
neurons the
are Nervous
generated
at different
dorsoventral
theEditon
embryonic spinal cord. Ventral interneurons (V0–V3) and motor
neurons (MN)Citation:
differentiate
from
in the
spinal SA,
cord.Hudspeth
Six classes
earlyS.dorsal
interneurons
to D6) Fifth
develop
in the
dorsal
half
Kandel
ER,progenitor
Schwartzdomains
JH, Jessell
TM,ventral
Siegelbaum
AJ,of
Mack
Principles
of Neural(D1
Science,
Editon;
2012
Available
of the spinal cord. (Adapted,
with permission,Accessed:
from Goulding
2002.)
at: http://mhmedical.com/
May et
10,al.2017
Copyright © 2017 McGraw-Hill Education. All rights reserved