Download 1) The main route of administration of a drug to produce a loca

1) The main route of administration of a drug to produce a local effect is:
A. Topical
B. Oral
C. Parenteral
2) The main routes of administration of a drug to provide a systemic effect
are:
A. Topical
B. Oral
C. Parenteral
3) Parenteral administration of a drug refers to the giving of a preparation:
A. Orally
B. Intradermally
C. Intramuscularly
D. Intravenously
4) Pharmacokinetics considers:
A. The way in which the body affects a drug by the processes of absorption,
distribution, metabolism and excretion.
B. The effects of the drug on the body and the mode of drug action.
C. The proportion of administered drug that is available to have an effect.
D. The removal of the drug by the liver before it has become available for use
5) If gut motility is increased then:
A. Drug absorption is decreased
B. Drug absorption is increased
C. Drug absorption is not effected
6) The rate of drug absorption is greatest in:
A. The small intestine
B. The large intestine
C. The stomach
7) Drug distribution may depend on tissue perfusion:
A. Highly vascular organs rapidly acquire a drug
B. Highly vascular organs acquire a drug slowly
C. Levels of a drug in bone may rise quickly due to its high vascularity
D. Levels of a drug in bone may rise slowly due to its reduced vascularity
8) Most drugs and metabolites are excreted by:
A. The kidneys
B. The Bile
C.The lungs
D. Perspiration, saliva and tears
9) Pharmacodynamics considers:
A. The way in which the body affects a drug
B. The effects of the drug on the body and the mode of drug action
C. Drug metabolism
10) A drug that binds to a cell receptor and causes a response is called an:
A. Agonist
B. Antagonist
C. Receptor blocker
11) A drug allergy occurs:
A. When too much drug has accumulated in an individual
B. When the body sees the drug as an antigen and an immune response is
established against the drug
C. An unwanted but predictable response to a drug
12) Factors affecting a client’s response to a drug include:
A. Body weight i.e. the larger the individual, the larger the area for drug distribution
B. Body fat – A loss of body fat stores means less drug available for activity
C. Body fat – An increase in body fat means greater sequestering in body fat and less
drug activity
D. The presence of certain foods
1. (A) True (B,C) False
2. (B,C) True (A) False
3. (B,C,D) True (A) False
4. (A) True (B,C,D) False
5. (A) True (B,C) False
6. (A) True (B,C) False
7. (A,D) True (B,C) False
8. (A) True (B,C,D) False
9. (B) True (A,C) False
10. (A) True (B,C) False
11. (B) True (A,C) False
12. (A,C,D) True (B) False