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Challenges in Latin America for
Implementing a Biorisk Management
Agenda
Leila Macedo, Ph.D.
www.anbio.org.br
www.anbiojovem.org.br
BWC, Green Cross Meeting,
Geneva, Dec. 2015
Founded in 1999
The Global Biosafety Network
• Today, IFBA’s global network has grown to 36 Member
Biosafety Associations
Globalization, World Flights and EID
Overview of EID Globalization
15.179 km of borders
CDC, 2014
Globalization and Emerging Diseases
Dengue
Socio-economic Impacts of EID
•
•
•
•
Impact on Employment
Impact on Economy and Global Trade
Fall in consumer confidence
Reduction of basic supplies like food, feed and
medicines
• Impact on Delivery of Health Care
• Impact on Transport, Travel, Tourism, and
Social Gatherings
Factors Contributing to Emerging
Infectious Diseases
Economic Impact of EID in the Americas
Pandemic flu in the US (projected):The
estimated economic impact of
Pandemic Influenza would be US$71.3
to $166.5 billion, excluding disruptions
to commerce and society.
Cholera in Peru:The outbreak of cholera in 1991 cost the
Peruvian fishing industry an estimated $775 million in lost
tourism and trade because of a temporary ban on seafood
exports.
SARS in Canada:
Research suggests a loss in national economic
activity in 2003 of roughly $1.5 billion, representing
0.15 percent of Canada’s real GDP. Real GDP in the
City of Toronto itself was lowered by $950 million, or
0.5 percent, with about $570 million of this total
concentrated in the travel and tourism sector.
Origin of Infectious Disease Threats
Globalization
Travel
Commerce
Naturally
Occurring
Biosafety
Negligence
Ineffective practices
Accidents
Accidentally
Occurring
Emerging
Endemic
Re-emerging
Biosecurity
IDT
Bioattack (Insiders)
Weaponized or simple
Mimic natural occuring
Deliberately
Occurring
Rapid Spread of Emerging Virus and New
Threats
Chikungunya Virus
Pillars of Biorisk Management
Life Sciences
Laboratories
Training
Biorisk
Management
Health Care
Network and
Intelligence
Coordination
Response
Surveillance
What skills are needed?
Emergency
Response
Infectious
diseases
Public
Health
Biosafety
&
Biosecurity
Regulatory
Framework
Epidemiology
International
Expertise
Laboratory
Information
Management
Multiple expertise needed !
Laboratories as source of
Biorisks
Possible Risks and Biothreats:
 Accidents of lab personnel
 Environment and healthepidemics (human and animal)
 Bioterrorism (att. Insiders)
 Economic impacts
 Impact in R&D
 Natural disasters
Survey of BSL3 Labs
Figure 1. The results of a survey conducted by ANBio about the state of biosafety and
biosecurity in biological research institutions across LA. The survey took place from
May 2008 to February 2009, and 237 questionnaires were received. (Published by
NAS, 2011)
Different Adequacies of Facilities
Unsecured Containment Laboratories
• These dangerous biological materials are not always well
secured within the “BSL3 containment laboratories”
Unsafe Laboratories
• Is Funding Available for?
Managing Geographic Challenges
Year 1952
Suspect Ebola Case
Pará
5,577km
Paraná
1,196 Km
Year 2000
Rio de Janeiro
Some Gaps to Build a Sustainable BRM
Agenda in Brazil
• Lack of existing Liability Measures: Biosafety Law just for
GMOs and non-enforcement required for other risks (Internal
rule 585, 2013 from Ministry of Defense for Mass Events);
anti-terrorism law in discussion;
• Lack of long term plans for Biosafety and Biosecurity,
including governmental funding for sensitive projects;
• Lack of national or institutional systems for accidents
notification with biological materials;
• Weak surveillance system for infectious diseases and
emergency response;
• Lack of Certified Biosafety Professionals;
• Inexistence of surveys/update of biological materials,
destruction of samples and lab’s condition;
• Weak Coordination among various stakeholders.
Leadership is key to Build The Biosafety Culture
(www.anbiojovem.org.br)
2015 More than
70.000 high
school students
in all states of
the country
We can’t Underestimate the Risk
Microbes Do Not Respect Borders
Cooperation is the only way for a safe world