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Transcript
1
CURRICULUM VITAE
Name
Sex
Birthdate
Nationality
Marital status
ROBERT, Benoît
Male
May 8, 1952
French
Married, no children
EDUCATION
1973
1974
1978
1985
M.S. in Physiology, University of Poitiers, France
M.S. in Biochemistry, University of Toulouse, France
First Doctoral Thesis in Molecular Biology, University of Paris
Doctoral Thesis in Molecular Biology, University of Paris
APPOINTMENTS AND POSITIONS
1975-1978
Fellowship from the Roux Foundation, to study transcription on isolated
chromatin and evaluate RNA complexity in cells from an embryonic carcinoma
cell line, in Pr. François Gros’ laboratory (Institut Pasteur, Paris).
1978-1987
Research assistant at the Institut Pasteur.
Working in Pr. François Gros' laboratory on the structure and organization of
contractile protein genes in the mouse genome, and their expression during
myogenesis.
1987-1995
Research assistant at the Institut Pasteur (Director of Research from 1992)
Working in Dr. Margaret Buckingham's laboratory on the role of the vertebrate
Msx homeobox genes in development.
1995-present Director of Research at the Institut Pasteur.
Head of the laboratory of Molecular Genetics of Morphogenesis.
Working on embryonic induction and vertebrate limb morphogenesis.
Honors
George Zermatti Foundation Prize in 1989.
Administrative Duties
Apr. 2000 - present
Project manager for the "Transverse Research Programs" of the Institut
Pasteur
Feb 2004 – Jan. 2008 Associate Principal Investigator in EuroStemCell, a European
Consortium for Stem Cell research
1
2
SELECTED PUBLICATIONS
Affara, N.A., Robert, B., Jacquet, M., Buckingham, M.E. and Gros, F. (1980) Changes in
gene expression during myogenic differentiation : I - Regulation of messenger RNA
sequences expressed during myotube formation. J. Mol. Biol. 140, 441-458
Robert, B., Daubas, P., Akimenko, M.A., Cohen, A., Guénet, J.L. and Buckingham, M.
(1984) A single locus in the mouse encodes both myosin light chains 1 and 3, a second locus
corresponds to a related pseudogene. Cell, 39, 129-140
Robert, B., Barton, P., Minty, A., Daubas, P., Weydert, A., Bonhomme, F., Catalan, J.,
Chazottes, D., Guénet, J.L. and Buckingham, M. (1985) Investigation of genetic linkage
between myosin and actin genes using an interspecific mouse back-cross. Nature, 314, 181183
Robert, B., Sassoon, D., Jacq, B., Gehring, W. and Buckingham, M. (1989) Hox-7, a mouse
homeobox gene with a novel pattern of expression during embryogenesis. EMBO J. 8, 91-100
Robert, B., Lyons, G., Simandl, B.K., Kuroiwa, A. and Buckingham, M. (1991) The apical
ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds.
Genes Dev. 5, 2363-2374
Houzelstein, D., Auda-Boucher, G., Tajbakhsh, S., Buckingham, M. E., Fontaine-Perus, J.,
and Robert, B. (1999). The homeobox gene Msx1 is expressed in the lateral dermomyotome
of a subset of somites, and in muscle progenitor cells migrating into the forelimb.
Development 126, 2689-2701
Houzelstein, D., Chéraud, Y., Auda-Boucher, G., Fontaine-Pérus, J. and Robert, B. (2000).
The expression of the homeobox gene Msx1 reveals two populations of dermal progenitor
cells originating from the somites. Development 127, 2155-2164.
Bach, A., Lallemand, Y., Nicola, M.-A., Ramos, C., Mathis, L., Maufras, M. and Robert, B.
(2003). Msx1 is required for dorsal diencephalon patterning. Development 130, 4025-4036.
Lallemand, Y., Nicola, M.-A., Ramos, C., Bach, A., Saint Cloment, C. and Robert, B. (2005).
Analysis of Msx ; Msx2 double mutants reveals multiple roles for Msx genes in limb
development. Development 132, 3003-3014.
Robert, B. and Lallemand, Y. (2006). Anteroposterior patterning in the limb and digit
specification: Contribution of mouse genetics. Dev Dyn 235, 2337-52.
Robert, B. (2007). Bone morphogenetic protein signaling in limb outgrowth and patterning.
Develop. Growth Differ. 49, 455–468.
Goupille O, Saint Cloment C, Lopes M, Montarras D, Robert, B. (2008) Msx1 and Msx2 are
expressed in sub-populations of vascular smooth muscle cells. Dev Dyn 237, 2187-2194.
2