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Isaac Precious Adaora, Kochubiei O., Vizir M.
Colorectal cancer: diagnosis and treatment.
Kharkiv National Medical University (Propedeutics to internal medicine, basis
of bioethics and biosafety department №1), Kharkiv, Ukraine.
Colon cancer is one of the most common malignancies. In the structure of cancer
morbidity in the world, colorectal cancer is currently in fourth place. Colon, or
colorectal, cancer is cancer that starts in the large intestine (colon) or the rectum (end
of the colon). Colorectal cancer treatment involves not only specific therapies for
curing or controlling the disease, but also strategies for meeting a patient's emotional
and physical needs.
The main types of treatment for colorectal cancer are surgery, radiation therapy,
and chemotherapy. Depending on the stage of the cancer, these treatments may be
combined. Surgery is the most effective treatment for local colorectal tumors. Very
small tumors can be removed through a colonoscope, but even with small tumors,
removing the portion of the colon containing the tumor, the surrounding fat, and
nearby lymph nodes is often the best treatment. Radiation therapy is treatment with
high-energy rays that destroy the cancer cells. For rectal cancer, radiation is usually
given after surgery, along with chemotherapy (known as adjuvant therapy), in order
to destroy any cancer cells left behind. For patients with stage IV disease that has
spread to the liver, treatments directed at the liver can be used. This may include:
Burning the cancer (ablation), delivering chemotherapy or radiation directly into the
liver, freezing the cancer (cryotherapy), surgery. Chemotherapy drugs are used to
treat various stages of colorectal cancer. They include 5-flurouracil, Xeloda,
Camptosar, and Eloxatin. These drugs are commonly used in combination with one
another. Chemotherapy is also used to improve symptoms and prolong survival in
patients with stage IV colon cancer. Monoclonal antibodies, including cetuximab
(Erbitux), panitumumab (Vectibix), bevacizumab (Avastin), and other drugs have
been used alone or in combination with chemotherapy. You may receive just one
type, or a combination of these drugs. There is some debate as to whether patients
with stage II colon cancer should receive chemotherapy after surgery. You should
discuss this with your oncologist.