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North East School Division Unpacking Outcomes Unpacking the Outcome Explore understandings Outcome (circle the verb and underline the qualifiers) BI30-GB1 Explore classical (i.e. Mendelian) and current (i.e. chromosomal) understandings of biological inheritance. KNOW UNDERSTAND BE ABLE TO DO Vocabulary: genetics, statistical analysis, probability, dominant, recessive, co-dominance, incomplete dominance, alleles, pedigree, genetic drift, x linked, sex-linked traits, genotype, phenotype, Punnett square, homozygous, heterozygous, Mendelian genetics, significance, generation, gene flow, natural selection, population, crossing-over, non-disjunction Gregor Mendel Key Concepts and How to’s: Evolution vs. Creation Identify gametes Create a continuum Inheritance of traits Passing of genes, alleles Dominance vs. recessive Punnett squares Mendels’ laws – law of segregation, law of independent assortment, law of dominance Chromosomal abnormalities Prior knowledge: Meiosis Passing of genes Reproduction Generations Probability Chromosomes and DNA That a shared vocabulary builds understanding of genetics That Gregor Mendel formed the basis for our modern understanding of genetics That the genetics of parents could result in a variety but not unlimited set of outcomes Pedigrees will identify generational inheritance Evolution plays a role in genetics That understanding in science develops and shifts over time That there are mechanisms that control inheritance and we can make predictions based on patterns A number of factors affect the prevalence of genes and alleles in populations Pose questions about why and how offspring only inherit some traits from their parents. Discuss the historical development of Mendelian genetics, including why Gregor Mendel is considered the “father of genetics”. Discuss the importance of probability in predicting the likelihood of inheriting particular traits. Discuss the historical development of scientific understanding of Mendelian genetics, including the importance of statistical analysis, probability, and significance. Distinguish among patterns of inheritance (i.e., dominant and recessive alleles, sex-linked traits, co-dominance, incomplete dominance, and multiple alleles) of heritable traits. Determine an organism’s phenotype from its genotype, and where possible, its genotype from its phenotype. Construct Punnett squares for monohybrid crosses using P1 genotypes (i.e., homozygous and heterozygous) to determine genotypic and phenotypic frequencies for F1 and F2 generations. Explore patterns of inheritance by interpreting pedigrees, including own family tree. Describe how gene flow, genetic drift and natural selection influence the property of alleles within a population. Recognize that scientists now understand chromosomes to be the mechanism of Mendel’s laws Investigate the importance of meiosis, including crossing-over, in genetic variation in gametes and non-disjunction in creating chromosomal abnormalities Identify, using karyotypes, chromosomal abnormalities and how these abnormalities may lead to chromosomal disorders such as Klinefelter syndrome, Down syndrome and Turner syndrome ESSENTIAL QUESTIONS How did Gregor Mendel influence a modern understanding of genetics through his experiments and as a result of his background? Why can two perfectly healthy plants pass on a genetic disease? Why are we better than we used to be, as humans? Should insurance companies have access to your genetic information? Before you select a life partner, should you check their genetics? Why does our understanding of science keep changing? Isn’t a fact a fact? How am I truly a product of my parents? Why am I not exactly half of one and half of another? How do I make predictions about traits based on my understanding of genetics? How do chromosomal abnormalities lead to chromosomal disorders?