Download Notes

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project

Document related concepts

Endomembrane system wikipedia , lookup

Tissue engineering wikipedia , lookup

Extracellular matrix wikipedia , lookup

Cell cycle wikipedia , lookup

Cytokinesis wikipedia , lookup

Cell encapsulation wikipedia , lookup

Cellular differentiation wikipedia , lookup

Cell growth wikipedia , lookup

JADE1 wikipedia , lookup

Cell culture wikipedia , lookup

Mitosis wikipedia , lookup

Organ-on-a-chip wikipedia , lookup

Amitosis wikipedia , lookup

List of types of proteins wikipedia , lookup

Transcript
ANALYSIS OF ENUMERATIVE DATA
"Enumerate" -- to count.
This type of data is usually generated by a process of observing, classifying, and
counting.
MULTINOMIAL EXPERIMENT
Same as a binomial experiment, except there are more than two outcomes for each
trial.
* n identical trials,
* k possible outcomes on each trial,
* trials must be independent (the outcome of one trial must not affect any
other trial),
* probability of each of the k possible outcomes must be constant from trial to
trial,
* of interest is the number of times each of the k possible outcomes occurs.
ONE-WAY (ONE-DIMENSIONAL) CHI-SQUARE (Χ²) TEST
H0: in the population, the distribution of occurrences conforms to some expected
distribution (such as the uniform distribution or the normal distribution).
Each of the k possible outcomes corresponds to a "cell." Cells may be arranged in a
one-row or a one-column table.
Each cell contains an observed number of outcomes (o), and an expected number of
outcomes (e).
The expected number (e) is derived from Ho.
The observed number (o) is the result of the experiment.
A chi-square (χ²) value is computed for each cell.
χ² for each cell = ( e - o )² / e.
The total χ² for all cells is the test statistic, the calculated-χ² (χ²c).
Ho is rejected if χ²c  χ²t and if p  
χ²t is based on α and d.f. (d.f. = number of cells - 1).
(d.f. = number of cells – 3 when the normal distribution is used.)
(d.f. = number of cells – 2 when the Poisson distribution is used.)
If ho is rejected, additional information should be reported as to the nature of the
deviation from the expected distribution.
This test is often used to test for the presence of a normally-distributed population.
For the sample size to be sufficient, the expected number (e) in each cell should
equal or exceed 5.
TWO-WAY (TWO DIMENSIONAL) CHI-SQUARE (Χ²) TEST -- CONTINGENCY TABLE
"Contingency" means dependency.
A two-way contingency table contains rows and columns, representing the two
variables under study. The number of rows = r ; the number of columns = c.
H0: in the population, there is independence between the row variable and the
column variable.
Ha: in the population, there is dependence between the row variable and the
column variable.
Each cell contains an observed number of outcomes (o), and an expected number of
outcomes (e).
The expected number (e) is derived from Ho, using the multiplicative rule for
independent events: If A and B are independent, then P(A B) = P(A) * P(B).
The observed number (o) is the result of the experiment, obtained by counting.
A chi-square (χ²) value is computed for each cell.
χ² for each cell = ( e - o )² / e.
The total χ² for all cells is the test statistic, the calculated-χ² (χ²c).
Ho is rejected if χ²c  χ²t and if p  
χ²t is based on  and d.f. (d.f. = [# of rows-1]*[# of columns-1] ).
If H0 is rejected, additional information should be reported as to the nature of the
dependencies.
For the sample size to be sufficient, the expected number (e) in each cell should
equal or exceed 5.