Download Protein Synthesis 1 - Transcription and Translation

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Transcript
AIM: How is the Genetic Code
Used?
.. / .-.. --- ...- . / _... .. __ _
Morse Code
1st Copy code
2nd Translate code
.
-
dot
dash
short sound
long sound
http://www.philtulga.com/morse.html
Is mRNA an identical copy of DNA?
NO!
Can you tell the difference?
RNA
DNA
DNA vs RNA
• DNA – main
•
instructions
• Double helix
•
• Sugar – Deoxyribose •
• Bases:
•
Adenine – Thymine
Guanine – Cytosine
RNA – copy of
instructions
Single helix
Sugar – Ribose
Bases:
Adenine – Uracil
Guanine – Cytosine
Replication is not DNA’s only job!
Coded
copy
change
It is also used to make
proteins
Transcription & Translation
Transcription - process by which a
DNA template is used to produce a
single-stranded RNA molecule.
Translation - process by which an
RNA molecule is used to direct the
production of a chain of specific
amino acids.
Where in the cell does this happen?
st
1
The genetic code needs to get
TRANSCRIBED into mRNA
m
The DNA base sequence needs to get
copied into messenger RNA
Why do we need a copy of the DNA?
The DNA are the main instructions
found in the nucleus, they can not leave
the nucleus.
Why not?
How is DNA transcribed into mRNA?
One side of the
DNA molecule
is the template
Transcription
RNA Polymerase
Is transcription the same as replication?
Transcription – coded copy of DNA to be
used to make proteins.
Replication - an identical copy of DNA to
be given to new cells.
Making mRNA
AUG……………
2nd the mRNA code needs to get
TRANSLATED into a protein
m
The mRNA copy
needs to get
changed into an
amino acid
sequence to
make a protein
How many mRNA bases = 1 amino acid?
codon
Amino acid
• Codon (3 mRNA bases) = 1 amino acid
Use the chart to translate the codon
UUU =
ACA =
CAC =
What did we learn?
• What are the two
jobs of DNA?
Replication & Protein
Synthesis
• How is replicationReplication = identical
different from
copy
transcription?
Transcription = coded
• What are the steps copy of information
of protein of DNA to mRNA,
Transcription
synthesis?
Translation into codon.
What did we learn?
• Compare transcription and
translation.
• How is DNA different from
mRNA?
DNA Bingo = DINGO
DNA / mRNA / Amino Acid
TAC
• AUG -MET (START)
CCA
•GGU – GLY
TTA
•AAU – ASP
AAC
•UUG – LEU
CTT
•GAA – GLU
TTT
•AAA – LYS
GCA
•CGU - ARG
AGC
•UCG – SER
TAG
•AUC – ISO
CAT
•GUA - VAL
AAA
•UUU – PHE
AGA
•UCU – SER
ACT
•UGA – STOP