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UNIVERSITY OF BELIZE Faculty of Nursing, Health Sciences and Social Work Department of Pharmacy CODE/COURSE: PHAR. 230 (THERAPEUTICS I ) CREDITS: 4 CREDIT HOURS SCHEDULE: Tuesdays and Thursdays; 5:00 – 6:50pm LECTURER: Mr. Eugene C. Echegi TEXT REQUIRED: [1] Current Medical Diagnosis & Treatment 38th Edition, Lawrence M. Tierney, Jr. Et al [2] Applied Therapeutics: The Clinical Use of Drugs: Mary Ann Kode-Kimble Et al 1992 [3] Merck Manual – Reference text COURSE DESCRIPTION: A study of the management of some of the major diseases and medical conditions prevalent in Belize, and its neighbouring countries. Students will need to combine information gained in Pharmacology, Physiology and Microbiology, so as to gain further insight into their etiology, presentation and complications of the conditions studied. Emphasis is placed on both drug and nondrug therapy with the aim of developing the student’s appreciation of rational and cost effective drug usage. RATIONAL: To develop the student’s knowledge so as to prepare them to become effective and efficient members of the health care team. COURSE OBJECTIVES: 1. To develop the students ability to make educated recommendations for costeffective therapy. 2. To provide the working knowledge needed to integrate diagnosing, prescribing and the role of the pharmacist. 3. To encourage students to be sensitive to the needs of the patients: ethically, legally and medically. 4. To develop a professional working relationship between the pharmacist, physician, nurse and other members of the health care team. COURSE CONTENT: 1) Body Fluids and Electrolyte Disorders Disease a. Distribution of Body Fluid b. Typical Fluid Fluxes c. Electrolytes d. Assessment of Fluid/Electrolyte Balance e. Fluid & Electrolyte Replacement Therapy f. Electrolyte and Dextrose Content of Various IV Fluids 2) Cardiovascular Disorders a. Angina Pectoris b. Hypertension c. Congestive Heart Failure (CHF) d. Myocardial Infarction (MI) e. Artherosclerosis f. Hyperlipidemia 3) Endocrine Disorders a. Diabetes mellitus b. Hormone synthesis and regulation c. Laboratory parameters d. Hyperthyroidism e. Hypothyroidism 4) Respiratory Disorders a. Disorders of the upper Airways: Asthma Chronic Obstructive Pulmonary Disease (COPD) Allergic Bronchopulmonary mycosis Bronchietctesis Cystic Fibrosis Bronchiolitis Obliterans b. Disorders of the Lower Airways: Tracheal obstruction Bronchial Obstruction Right middle lobe syndrom 5) Infectious Disorders a. Bacterial Infections b. Fungal Infections c. Viral Infections d. Helminthic Infections e. Other Parasitic Infections 6) Conception Contraception a. The female menstrual cycle b. Conception c. Contraception 7) Course Review CLASS POLICIES: Students are responsible for all notes, tests and assignments. No make up quizzes will be allowed. No prior notice will be given before a quiz A week’s notice will be given before a test Excuses due to illness must be made before the test begins. Unexcused absence from a test will mean an automatic zero. Five points will be deducted for each day a paper or assignment is late, up to 8 (working) days. Passing grade for quizzes, tests and exams is 75% GRADING: Semester Work Test - 40% (at least 3) Quizzes – 10% (at least 2) Term paper and attendance – 10% (at least one (1) Term paper) Final Examination: 40% (comprehensive) CLASS RULES: Proper Dressing (Formal); No eating; No chattering; No phone calls, and reception during classes; No walking about; No playing, we are in serious business – moulding your future!!! Thanks for anticipated understanding and co-operation. It is your responsibility to come prepared to receive the lecture, and to ask questions, and clear any doubts or misunderstanding during your personal studies at home. You are expected, and urged to read the topics before coming for the lectures. This will enable you to understand the lectures better, and to follow easier. I wish you a wonderful, vibrant and successful semester. Congratulations in advance!!! Eugene C. Echegi Preamble: As medical sciences continue to broaden; as diseases continue to present complexities; as physicians continue to focus on specific fields; as resistance to drugs by different microbes increases; as new analytical methods becomes available, and highly potent drugs becomes isolated from crude sources, with attendant increase in drug interactions; as new methods and machines take up certain previous roles of the pharmacist: We have to reevaluate our responsibilities to the patient and the health sector towards finding more useful role that will enable us to be most effective and useful to the health care team especially in an era where patient care is considered the primary focus of every health personnel: Hence the entrance, importance and new focus on therapeutics. It may be logical therefore to consider it the most important course for today’s pharmacist.