Download Physiology and Cell Biology Research Day

The 7th Annual
Physiology and Cell Biology
Research Day
OSU Biomedical Research Tower
March 29, 2013
Organizing committee: B. Biesiadecki, V. Fedorov, M. Treon,
N. Weisleder and M. Ziolo
Schedule of Events
10:30-10:45
Opening Remarks
BRT Rm 115
10:45-12:00
Emil Bozler Lecture
BRT Rm 115
Lynda F. Bonewald, Ph.D.
12:00-12:45
Light lunch
BRT Rm 115
12:45-1:30
Oral Session
BRT Rm 115
1:30-3:30
Poster Session
BRT Lobby
3:30-4:30
Nishikawara Scholars
Oral presentations
BRT Rm 115
4:30-4:45
Awards presentation
BRT Rm 115
(Nishikawara Scholars and Poster awards)
5:00
Off-campus social
Eddie George’s restaurant (South Campus Gateway)
Poster Presentations
1:30-3:30 P.M.
* Poster Presenters:
- Please mount your posters from 10:00-10:30 A.M.
- Poster presentation and judging will be at 1:30-3:30 P.M.
Odd numbered posters will be presented at 1:30-2:30.
Even numbered posters will be presented at 2:30-3:30.
Presenters should be at their poster during this time.
P1. Endogenous Capsaicin-Like Lipids in Guinea Pig and
Human Small Intestine.
X.-Y. Wang, G-D Wang and JD Wood
P2. Purinergic Inhibitory Neuromuscular Transmission in
Human Jejunum and Guinea Pig Colon.
X.-Y. Wang, JD Wood and G-D Wang
P3. Sarcolipin Increases Energy Expenditure and Provides
Resistance Against Diet-induced Obesity.
Santosh K. Maurya, N.C. Bal, D.H. Sopariwala, S.A. Shaikh,
L.A. Rowland and M. Periasamy
P4. Synchronization of Ca2+ Release in Multicellular Cardiac
Preparations.
Jessica L. Slabaugh, L. Brunello, S. Gyorke and P.M.L.
Janssen
P5. Myosin 9b Regulates Osteoclast Function Through Rho
and Src.
Brooke McMichael, K. Scherer, N. Franklin and B. Lee
P6. Mechanisms of Junctional Membrane Uncoupling in the
Progression of Heart Failure.
Sayak Bhattacharya, J. Alloush, E. Beck and N. Weisleder
P7. Evaluation of the Therapeutic Effects of Tripartite Motif
Family Proteins on Muscular Dystophy.
Heather Manring, Z. Xu, J. Alloush, E. Beck, L. Gushchina and
N. Weisleder
P8. Developing Novel TRIM Family Proteins as Therapeutic
Agents for Chronic Diseases.
Liubov Gushchina, J. Alloush, E. Beck, H. Manring, Z. Xu and
N. Weisleder
P9. Myocardial Rac1 Exhibits Partial Involvement in ThyroxinInduced Cardiomyocyte Hypertrophy and its Inhibition is
Not Sufficient to Improve Cardiac Dysfunction or
Contractile Abnormalities in Mouse Papillary Muscles.
Mohammad T. Elnakish, L. Moldovan, H.H. Hassanain and
P.M.L. Janssen
P10. Restoring Nitroso-redox Equilibrium After Myocardial
Infarction Limits Contractile Dysfunction and Adverse
Remodeling.
Bo Zhang, H. Wang, X. Huang, C. Heymes, E. Villamena, R.J.
Gumina and M.T. Ziolo
P11. NOS1 Orchestrates a Localized Nitroso-redox Signaling
Network in Ventricular Myocytes.
Honglan Wang, L. Tang, B. Zhang, S.R. Roof, X. Huang, L.S.
Kirschner, F. Villamena, B.J. Biesiadecki and M.T. Ziolo
P12. Spinal Cord Contusion Induces Extracellular SignalRegulated Kinase (ERK)1/2 Activation Early After Injury.
Kent E. Williams and L.B. Jakeman
P13. Targeted Delivery of NIS--‐Specific Knockdown Agents to
the Mouse Salivary Gland.
Brynn Hollingsworth, K.M.D. La Perle, M.P. Brandt and S.M.
Jhiang
P14. Dynamic Interplay of Smooth Muscle α-Actin GeneRegulatory Proteins Reflects the Biological Complexity of
Myofibroblast Differentiation.
Bill Willis, S. Hariharan and A.R. Strauch
P15. HuR mRNA Isoform Expression in Cellular Energy
Depletion.
Suman S. Govindaraju and B.S. Lee
P16. Contribution of the NOS1/CaMKII/RyR Axis in the Positive
Inotropic Response to Beta-adrenergic Stimulation in
Ventricular Myocytes.
Lifei Tang, S.R. Roof, X. Huang, P.J. Mohler, X.H. Wehrens
and M.T. Ziolo
P17. The Role of Increased Sarcolipin Expression in Neonatal
Development and in Muscle Disease.
Meghna Pant, N.C. Bal, D. Delfin, J. Rafael-Fortney and M.
Periasamy
P18. Sarcolipin and Ucp1 Play Distinct Roles in Diet- Versus
Cold-induced Thermogenesis.
Leslie Rowland, N.C. Bal and M. Periasamy
P19. Development of a Striated Muscle Contractile Function
Assay in Developing Zebrafish.
Neha Rastogi, J.P. Davis, S.L. Amacher, C.E. Beattie and
P.M.L. Janssen
P20. Adenosine A1 Receptors Overexpression in the
Pacemaker Complex Aggravate Atrial Tachy-Brady
Arrhythmias in Canine and Human Chronic Heart Failure.
Lori Hage, O. Fedorenko, B. Hansen, Q. Lou, A.
Kalyanasundaram, A.V. Glukhov, I.M. Bonilla Mercado, R.S.D.
Higgins, A. Kilic, D. Van Wagoner, S. Gyorke, P.M.L. Janssen,
P.J. Mohler, R. Weiss, B.J. Biesiadecki, C.A. Carnes and V.V.
Fedorov
P21. Characterization of CD200 and CD200R Expression After
Spinal Cord Injury.
Bryan Brautigam and L.B. Jakeman
P22. Adapting Stress Responses in Plants to the Mammal: Step
One.
Shane D. Walton, V. Shettigar, C.W. Wilson, P.D. Conley, A.J.
O’Neil and J.P. Davis
P23. Calcium and Magnesium Binding Properties of Soybean
Calmodulin 1 and 4.
Vikram Shettigar J. Zhang, A.J. O’Neil, S.D. Walton, H.
Chakravarthy, and J.P. Davis
P24. The Roles of Kindlin 3 in Osteoclast Function.
(Nishikawara 2012 Summer Undergraduate Fellow)
Jordan Brauner and B.S. Lee
P25. The Role of Myoferlin in the Differentiation and
Multinucleation of Osteoclasts.
(Nishikawara 2012 Summer Undergraduate Fellow)
Lauren Savage, B. McMichael and B.S. Lee
Oral Presentations
12:45-1:30 P.M.
1. Enhanced Sensitivity to Adenosine in Chronic Heart Failure
Aggravate Atrial Tachy-Brady Arrhythmias.
(Nishikawara 2012 Summer Undergraduate Fellow)
Brian Hansen, Q. Lou, L. Hage, O. Fedorenko, A.
Kalyanasundaram, A.V. Glukhov, I.M. Bonilla, S. Györke, P.M.L.
Janssen, D.R. Van Wagoner, P.J. Mohler, R. Weiss, B.J.
Biesiadecki, C.A. Carnes, V.V. Fedorov
2. Apigenin enhances Akti1/2-induced Radioactive Iodine
Uptake (RAIU) in Thyroid Cells in p38 MAPK Activitydependent Manner.
Aparna Lakshmanan, S.M. Jhiang
3. Sarcolipin Interaction With SERCA is Distinct from
Phospholamban; Only Sarcolipin Can Promote Uncoupling of
the SERCA Pump.
Sanjaya K. Sahoo, S.A. Shaikh, D.H. Sopariwala, N.C. Bal and
M. Periasamy
4. Targeting Membrane Repair as a Therapeutic Approach for
Myocardial Ischemic Injury.
Zhaobin Xu, J. Alloush, E. Beck, H. Manring, L. Gushchina, N.
Weisleder
Nishikawara Presentations
3:30-4:30 P.M.
Margaret T. Nishikawara (1975)
Nima Milani-Nejad
“Effect of Muscle Length on Cross-bridge Cycling Kinetics in
Intact Cardiac Trabeculae Under Near-physiological
Conditions: Studies from Rodents to Humans Using a Novel
Approach”
Benjamin Nixon
“Troponin I Serine 150 Phosphorylation Imparts Protection
From pH-Induced Troponin Ca2+ Desensitization”
Hsiang-Ting Ho
“RyR Phosphorylation by Oxidized CAMKII Contributes to the
Cardiotoxic Effects of Cardiac Glycosides”
Emil Bozler Distinguished Lecture
Department of Physiology and Cell Biology
Lynda F. Bonewald, Ph.D.
Lefkowitz Professor of Oral Physiology
Vice Chancellor for Translational Clinical Research
Director, UMKC Center of Excellence
in the Study of Dental and Musculoskeletal Tissues
University of Missouri at Kansas City
“Muscle and Bone Interactions”
Friday, March 29, 2013 - 10:45 A.M.
BRT Room 115