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Course Specifications: Clinical physiology University : Assiut Faculty : Medicine Department offering the programme : Clinical physiology. Department offering the course : Clinical physiology. Academic year/ level : Ist year A- Basic Information Title : Physiology Hours : Code : 2 lectures: 99 Tutorial : Practical : 34 Total: 133 B- Professional Information: 1-Overall aims of course : -Know about and recognize the normal structure and function of the body and of each of its major systems. - Acquire an appropriate functional background of cells, tissues, organs & systems . - Describe the integration of physiological functions which characterize the performance of the human body as a whole in health . - Know the physiological principles underlying diseases states that aids in interpretation of symptoms . 2- Intended learning out comes of the course (ILOs) Knowledge and Understanding: By the end of the course, students should be able to: a1- Describe the cellular functions at the organelle and molecular levels. a2- Describe the structure and functions of the ANS, its higher centers ,autonomic receptors and chemical transmitters. 1 a3- mention the general components of blood and its functions, mechanism of blood coagulation and regulation of blood volume and understand some of clinical conditions occurring due to deficiency of one or more of the blood components. a4- mention the properties of the cardiac muscle and factors affecting them, special circulations. understand the circulatory system and different related aspect. a5-- Describe the functional structure of the respiratory system ,, respiratory cycle, its mechanism, regulation of normal respiration , respiratory functions of the blood and some conditions related to disorders of the respiratory system 6- Explain the general mechanism of the gastrointestinal secretion, components of functions of different parts of the digestive system ,, the mechanism of absorption , types of GIT movements and some clinical conditions which result due to disturbances of functions a7- mention the properties of excitability of living tissues , membrane potentials , and their relation to different phases of excitability , physiological anatomy of the skeletal muscle and mechanism of contraction and changes occurring during it. Practical Skills by the end of tthe course, students should be able to c1- Perform hernatological tests estimation of blood Hb. bleeding and clotting times ,. blood groups and read the ESR. c2- Perform the most important respiratory functions tests. c3- Perform the measurement the arterial blood pressure. c4- Use the stethoscope to hear the heart sounds and respiratoiy sounds. c5- Record and read the ECG. c6- Dissect the frog and perform experiments of (simple muscle twitch, factors affecting it properties of the cardiac muscle and factors affecting it). Intellectual Skills: 2 fly the end o/ the course, students should he able to: b1- Interpret the most important physiological laboratory results (blood , respiratory , CVS. N& M) to distinguish the physiological form from the pathological conditions. b2- To comment on some clinical parameters (ABP, ECG , ESR, Blood fragility test, nonnal heart rate , factors affecting it, nerve coduction and velocity, normal pulmonary function tests). -b3Integrate physiology with other basic and clinical science. General Skills and Attitudes: By the end of the course, students should be able to: dI - Work separately or in a team to research and prepare a scientific topic. d2- Present physiological data in a graphical form. 3 - Contents : Topics Cell physiology No. of hours ANS Blood CVS Respiration Musle and nerve Digestion Lectures 5 7 20 42-46 18-20 21-22 5 7 10 32-36 16-18 9-10 14 14 Tutorial /Practical 10 12 2 12 4- Teaching methods : Lectures and lab (practical training ) using : 4.1- Overhead projectors 3 4.2- Data show power point 4.3- White board 4.4-Closed circuit 5- Student Assessment Methods : 5.1- Written exams to assess the understanding (a1-a7,b1-b3) Multiple choice questions. Essay questions. 5.2- Oral exam to asses ability for comprehensive discussion (a1-a7,b1-b3) . 5.3- Practical exam to assess ability to recognize ,interpret , describe and perform different physiological laboratory tests (c1-c6,d1-d2). Assessment Schedule : Assessment 1…….continuous assessment in the 10th week. Assessment 2…….continuous assessment in the 15 th week . Assessment 3…….continuous assessment in the 24 th week . Assessment 4…… Final practical exam . in the the 28th week. Assessment 5…… Final written exam . in the the 34th week. Assessment 6…… Final oral exam . in the the 34th week. Weighting of Assessments: Continuous assessment Final exam Oral exam Practical exam (practical book Assessment & attendance mark) Total 20 % 48% 20% 12% 100% 6- List of References : 6.1- Course Notes Notes on Physiology and practical book by staff members of Physiology department. 6.2- Essential Book (Text Books) Guyton . 6.3- Recommended books: Ganon. 6.4- Periodicals , Web sites, etc. American journal of Physiology. 4 7- Facilities required for teaching and learning Overhead projectors , data show,computers . Course Schedule Learning objectives: A-Knowledge and Understanding : By the end of the course , students should be able to : Cell physiology a.1. Describe the cellular functions at the organelle and molecular levels . Autonomic Nervous System (ANS): a.1. Describe the structure and functions of the ANS , a.2 know its higher centers . a.3. Decribe the autonomic receptors and chemical transmitters . a.4. Know the denervation hypersensitivity , tonic activity and higher control of the ANS. Blood : a.1.Know the general components of blood and its functions ,. a.2. Describe the mechanism of blood coagulation . a.3 Know the regulation of blood volume . a.4.Know the blood groups. a.5. Understand some of clinical conditions occurring due to deficiency of one or more of the blood components . Cardiovascular System:(CVS) a.1.Know the properties of the cardiac muscle and factors affecting them a.2.Describe the cardiac cycle . a.3.Know the innervation of the heart. a.4. Know the regulation of the heart rate. a.5.Describe the special circulations. 5 a.6.Understand the circulatory system and different related aspect . Respiratory System: a.1.Describe the functional structure of the respiratory system . a.2. Describe the respiratory cycle, its mechanism . a.3.Know the regulation of normal respiration . a.4.Know the respiratory functions of the blood and some conditions related to disorders of the respiratory system . Digestive System : a.1.Explain the general mechanism of the gastrointestinal secretion . a.2. Know the components of functions of different parts of the digestive system a.3.Describe the mechanism of absorption , types of GIT movements and some clinical conditions which result due to disturbances of functions . Nerve and Muscle: a.1.Know the properties of excitability of living tissues . a.2. Describe the membrane potentials , their relation to different phases of excitability , a.3.Know the physiological anatomy of the skeletal muscle. a.4.Know the mechanism of contraction and changes occurring during it . a.5.Describe the oxygen debt mechanism and mechanical efficiency. B -Intellectual Skills : By the end of the course , students should be able to : Blood : b.1. Interpret the most important physiological laboratory results to distinguish the physiological from the pathological conditions. b.2.Intrpret the different blood groups. b.3.Evalute the normal components of the blood . 6 b.4. comment on some clinical parameters ESR and Blood fragility test . Cardiovascular System: b.1.To comment on ABP. b.2. Comment on ECG b.3.Comment on normal heart rate and factors affecting it. Respiratory System: b.1. Comment on different respiratory functions tests. Digestive System: b.1. Comment on the normal function of the gastrointestinal tract. Nerve and Muscle: b.1. Comment on nerve coduction . b.2. Comment on nerve velocity. b.3. Comment on types of contractions of smooth and skeletal muscles. Autonomic Nervous System: b.1.Comment on the normal structure and function of this system . b.2. Comment on the types of the autonomic receptors. C-Practical Skills : By the end of the course , students should be able to : Blood c.1. Perform hematological tests : estimation oh blood Hb,. c.2. Perform bleeding and clotting times . c.3. Determine the blood groups and read the ESR . Cardiovascular System: c.1. Perform the measurement the arterial blood pressure . c.2. Use the stethoscope to hear the heart sounds Record and read the ECG. 7 c.3. Dissect the frog and perform experiments of properties of the cardiac muscle and factors affecting it . Respiratory System : c.1. Perform the most important respiratory functions tests . c.2. Use the stethoscope to hear the respiratory sounds . Nerve and Muscle: c.1. Dissect the frog . c.2. perform experiments of (simple muscle twitch, factors affecting it , D-General and transferable skills : By the end of the course , students should be able to : d.1. Work separately or in a team to research and prepare a scientific topic . d.2. Involvement of students in active learning. Topics Teaching methods Covered ILOs Hours Cell Physiology Lectures a.1 4 Time Whom Dr/Marwa A Abd El aziz Lectures a.1 – a .4 Physiology of ANS 7 Lectures a.1- a.5 10 Practical b.1-b.4 c.1 – c.3 a.1-a.6 10 Blood Lectures CVS 32 -36 Dr. Nashwa Ali Prof/ Salwa Saleem Prof/Mahmoud Dr/ Omayma 8 Practical Lectures b.1- b.3 c.1 –c.3 a.1 –a.4 12 16- 18 Respiration Practical Lectures b.1 c.1-c.2 a.1- a.5 Practical b.1 –b.3 c.1 –c.2 2 9- 10 Nerve and muscle Digestive system Lectures a.1 –a.3 b .1 Dr/ Mona Farouk Dr/ Marwa A. Dr/Nashwa Ali 10 14 Prof/ Mostafa Gaber Course Coordinators: Prof .Dr. Manal Mahmoud Abd Elmaged Dr. Marwa Abd Elaziz Head of Department: Prof . Mahamed Awed 9 10