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Objective
What: Compare mitotic stages of cancer cells to
normal cells.
How: By Looking at cells during different stages of
Mitosis in cancer & normal cells.
Why: So that we can understand what people who
have gone through cancer treatments feel.
Warm UP:
1.What are the 6 stages of Mitosis?
2.What happens during Metaphase?
The Cell Cycle and Cancer
Ted Talk Audio
http://ed.ted.com/lessons/how-docancer-cells-behave-differently-fromhealthy-ones-george-zaidan
Answer the following Questions during the video:
1. Finish this sentence:
Growth occurs when
______________________________________________________________________
______________________________________________________________________
2. What is a mutation?
______________________________________________________________________
______________________________________________________________________
3. Radiation works by…..
______________________________________________________________________
______________________________________________________________________
4. What is the problem with healthy cells during radiation and chemotherapy treatments?
______________________________________________________________________
______________________________________________________________________
Page 3
Virtual Lab Website
Google:
Glencoe cancer cell virtual lab
Page 4
Glencoe Cancer Cell Virtual Lab
If this site doesn’t load the first time
google:
Glencoe cancer cell virtual lab
Page 5
Henrietta Lacks Video
http://www.cbsnews.com/news/theimmortal-henrietta-lacks/
Page 6
The Stages of the Cell Cycle
1. Click on picture for cell cycle animation –
will go to www.cancerquest.org)
2. Use alt-tab keys to go between website
and power point presentation.
3. Click on blank space to proceed to next slide.)
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There are several factors that regulate the cell
cycle and assure a cell divides correctly.
1.Before a cell divides, the
DNA is checked to
make sure it has
replicated correctly.
If DNA does not copy
itself correctly, a gene
mutation occurs.
DNA replication animation:click
on DNA picture
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2. Chemical Signals tell a cell when to
start and stop dividing.
(Target cells animation: click on go
sign)
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Neighboring cells communicate with
dividing cells to regulate their growth also.
(Normal contact inhibition animation: click on petri dish)
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Cancer is a disease of the cell cycle. Some of
the body’s cells divide uncontrollably and
tumors form.
Tumors in Liver
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Tumor in Colon
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DNA mutations disrupt the cell cycle.
Mutations may be caused
by the following
carcinogens:
1. radiation
2. smoking
3. Pollutants
4. chemicals
5. viruses
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While normal cells will stop dividing if there is a mutation in
the DNA, cancer cells will continue to divide with mutation.
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Due to DNA mutations, cancer cells ignore the chemical
signals that start and stop the cell cycle.
2 animations of cancer cells dividing: click on picture
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Due to DNA mutations, cancer cells cannot
communicate with neighboring cells. Cells continue
to grow and form tumors.
Skin cancer
(cancer cells dividing: click on picture.)
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SUMMARY
Normal Cell Division
1. DNA is replicated properly.
2. Chemical signals start and
stop the cell cycle.
3. Cells communicate with
each other so they don’t
become overcrowded.
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Cancer Cells
1. Mutations occur in the
DNA when it is replicated.
2. Chemical signals that start
and stop the cell cycle are
ignored.
3. Cells do not communicate
with each other and
tumors form.
Page 16
Treating Cancers
Cancer treatments include drugs that can stop cancer
cells from dividing.
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This powerpoint was kindly donated to
www.worldofteaching.com
http://www.worldofteaching.com is home to over a
thousand powerpoints submitted by teachers. This is a
completely free site and requires no registration. Please
visit and I hope it will help in your teaching.
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