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Ashley Herring Marx, PharmD, BCPS CURRICULUM VITAE February 2015 Work: UNC Medical Center 101 Manning Dr Chapel Hill, NC 27514 Home: 5512 Sutteridge Ct Durham, NC 27713 [email protected] EDUCATION 2006-2007 PGY2, Infectious Diseases Wake Forest Baptist Health Winston-Salem, NC 2004-2005 PGY1 Medical University of South Carolina Charleston, SC 1999-2004 UNC Eshelman School of Pharmacy Chapel Hill, NC Doctor of Pharmacy with Honors and Distinction 1995-1999 University of North Carolina at Chapel Hill Chapel Hill, NC Bachelor of Science with Highest Distinction, Biology PROFESSIONAL EXPERIENCE 2013-current Clinical Pharmacy Specialist, Infectious Diseases University of North Carolina Medical Center Assistant Professor for Clinical Education Division of Practice Advancement and Clinical Education UNC Eshelman School of Pharmacy, Chapel Hill, NC • Provide clinical pharmacy services in support of ID consultants on general and immunocompromised host services, and on infectious disease-focused medicine team. • Additional hospital services: Anti-Infective Subcommittee member; UNC Outpatient Parenteral Antimicrobial Therapy (OPAT) program consultant pharmacist; Lead pharmacist for Antimicrobial Stewardship Program; Coordinator, UNC Code Sepsis Initiative. • Coordinate infectious diseases pharmacotherapy module (PHCY449) for pharmacy students. • Lecturer, Infectious Diseases elective (DPET811). • Provide clinical rotations for pharmacy students, PGY1, and PGY2 residents. 2011-2013 Clinical Assistant Professor, Department of Pharmacotherapy and Outcomes Sciences Virginia Commonwealth University School of Pharmacy Richmond, VA 2009-2013 Clinical Pharmacy Specialist, Infectious Diseases Inova Fairfax Hospital Falls Church, VA • Developed new antimicrobial stewardship program in mixed teaching/community hospital environment. • Provide daily surveillance and intervention support for the Inova Fairfax Hospital antimicrobial stewardship program. • Coordinated antimicrobial stewardship initiatives and formulary management for 5-hospital health system. • Developed and maintained a n t i m i c r o b i a l order sets and decision-support tools for computerized physician order entry systems (GECE, EpicCare). • Provided clinical pharmacy services in support of staff pharmacists and ID consultants. • Developed competency modules for pharmacy department employees regarding anti-infective therapies. • Precepted infectious diseases rotations for PGY-1 residents and Doctor of Pharmacy candidates. • Co-chair of the Inova Health System Antimicrobial Subcommittee. • Served as pharmacy representative on Sepsis, Infection Control and Prevention, and Surgical Care and Infection Prevention Committees. 2007-2009 Clinical Pharmacist, Infectious Diseases Emory University Hospital Midtown Atlanta, GA • Provided system-wide antimicrobial surveillance activities including prospective audit and feedback to academic and community prescribers. • Coordinator of the Emory Healthcare Antimicrobial Usage Committee (subcommittee of Pharmacy and Therapeutics committee) including formulary management, development and implementation of antimicrobial policies. • Provided pharmacotherapy services including kinetics and anticoagulation monitoring, patient counseling, and targeted medication histories for patients on ID consult teams and other hospital units. • Provided pharmacokinetic orientation to pharmacy staff and PGY-1 residents. • Precepted infectious diseases rotations for PGY-1 residents, medical residents, and Doctor of Pharmacy candidates. • Served as chair of PGY-1 Research Committee. 2004-2006 Clinical Pharmacist Medical University Hospital Charleston, SC • Facilitated proper selection, distribution, administration, and monitoring of medications for patients in the Heart and Vascular Center and Coronary Care Unit. • Provided therapeutic consults and patient counseling services as requested. • Assisted in training of new pharmacy staff and residents. 2005-2007 Pharmacist (PRN) Walgreen’s Pharmacy Charleston, SC and Winston-Salem, NC 2003 Research Assistant University of North Carolina Eshelman School of Pharmacy Chapel Hill, NC Screened and consented patients for clinical studies of intestinal UDPglucuronosyltransferase enzyme activity. Participated in protocol writing and revision. Prepared regulatory documents and IRB submissions for new and ongoing clinical protocols. Assisted in adaptation of published HPLC probe assay with new internal standards. 2000-2001 Laboratory Research Assistant The Henry M. Jackson Foundation for the Advancement of Military Medicine, United States Military HIV Research Program affiliate Rockville, MD Conducted basic research in support of Phase I trials of HIV vaccines. Cultured autologous dendritic cells and conducted quality assurance testing for human reinfusion protocol. Performed ELISA and ELISpot immunoassays in support of HIV vaccine trials. Assisted in volunteer recruitment and screening visits. Regulatory Affairs Specialist Prepared IND updates for the FDA. Organized and maintained regulatory records of ongoing and archived clinical trials. Published weekly progress reports of ongoing clinical trials. LICENSURE AND CERTIFICATION 2004-current Pharmacist 18234, North Carolina Board of Pharmacy 2005-current Board Certified Pharmacotherapy Specialist, American College of Clinical Pharmacy RESEARCH EXPERIENCE 2014-2015 Clinical evaluation of posaconazole therapeutic drug monitoring comparing delayed release tablets and oral suspension formulations. UNC Medical Center Chapel Hill, NC Faculty Advisor for PGY2 research project. PI: Jacqueline Isip, PharmD. Co-investigators: Pearlie Chong, MD; Maurice Alexander, PharmD, BCOP; Jill Bates, PharmD, BCOP; Anastasia Ivanova; Madison Bushman, PharmD Candidate. 2014-2015 Use of proton-pump inhibitors and histamine type-2 antagonists among patients with C. difficile associated diarrhea. UNC Medical Center Chapel Hill, NC Faculty Advisor for Clinical Scholars Track student project. Coinvestigator, Harrison Lyle, PharmD Candidate. 2012-2013 Development of disease-state-specific antibiograms for outpatient emergency department population. Inova Fairfax Hospital Falls Church, VA Co-Investigators: Jessica Schnur, PharmD; Mona Shah, PharmD, BCPS 2011-2012 Appropriateness of initial therapy for community-acquired pneumonia and healthcare-associated pneumonia in patients admitted through the emergency department. Inova Fairfax Hospital Falls Church, VA Co-Investigator: Jenna T. Smith, PharmD 2010-2012 Clinical outcomes associated with doripenem as initial empiric therapy in febrile neutropenic cancer patients. Inova Fairfax Hospital Falls Church, VA Co-Investigators: Joseph Gibbons, PharmD; Steven Willis, PharmD; Leila Mohassel, PharmD, BCOP 2010-2011 Antibiotic selection and duration for urinary tract infections on hospitalist medicine teaching teams at a community teaching hospital. Inova Fairfax Hospital Falls Church, VA Co-Investigators: Anne Rain Tanner, PharmD; Alisa Escano, PharmD, BCPS 2008-2009 Antibiotic consumption and infection rates in intensive care units. Emory University Hospital Midtown Atlanta, GA Co-Investigators: Jesse Jacob, MD; James Steinberg, MD 2006-2007 Correlation of vancomycin exposure and outcomes in adult patients with methicillin-resistant Staphylococcus aureus pneumonia. Wake Forest University Baptist Medical Center Winston-Salem, NC Co-Investigators: James Johnson, PharmD, BCPS; John Williamson, PharmD, BCPS 2004-2005 2004-2005 2002-2004 Analysis of perioperative antimicrobial dosing: a process improvement intervention for Surgical Infection Prevention (SIP) Medical University of South Carolina Charleston, SC Co-Investigator: G. Mark Baillie, PharmD, MHA, BCPS Screening and monitoring for potential metabolic effects of atypical antipsychotics Medical University of South Carolina Charleston, SC Advisor: Amy Vandenberg, PharmD, BCPP Correlation of plasma levels of pro-inflammatory cytokines with CYP1A2, CYP2D6, and CYP3A activity measured by cocktail phenotyping in HIV positive patients, compared with non-infected controls UNC Eshelman School of Pharmacy Chapel Hill, NC Advisor: Angela D.M. Kashuba, BS Pharm, PharmD TEACHING EXPERIENCE 2015-current Lecturer, ID Elective UNC Eshelman School of Pharmacy Chapel Hill, NC 2014-current Lecturer, ID Fellows Core Curriculum and ID Boot Camp UNC School of Medicine Chapel Hill, NC 2013-current Coordinator and lecturer, ID Therapeutics Module UNC Eshelman School of Pharmacy Chapel Hill, NC 2010-2012 Lecturer, ID Therapeutics Module Virginia Commonwealth University School of Pharmacy Falls Church, VA 2008 Lecturer, Medical-Surgical Nursing Certification Course Emory University School of Nursing and Emory Healthcare Atlanta, GA 2008-2009 Lecturer, ID Fellows Didactic Course Emory Healthcare and Emory University School of Medicine Atlanta, GA 2008-2009 Preceptor, Infectious Diseases rotation Required and elective rotations for 4 PGY-1 residents Emory University Hospital Midtown Atlanta, GA 2008-2009 University of Georgia School of Pharmacy Preceptor, Infectious Diseases and Acute Care rotations Emory University Hospital Midtown Atlanta, GA 2004-2005 Preceptor, Pharmacy Experience Units I and II (IPPE) Medical University of South Carolina School of Pharmacy Charleston, SC 2002-2003 Laboratory Teaching Assistant UNC Eshelman School of Pharmacy Chapel Hill, NC POSTERS AND PUBLICATIONS Banoub M, and Marx, AH. Retrospective evaluation of the treatment of vancomycin-resistant enterococcal bloodstream infections at an academic medical center. Presented at the 49th Annual Midyear Clinical Meeting of the American Society of Health-System Pharmacists, Anaheim, CA, December 2014. Schnur J, Marx A, and Shah M. Evaluation of current antibiotic resistance patterns among local uropathogens in the outpatient treatment of urinary tract infections. Presented at the 32nd Annual Eastern States Resident Conference, Hershey, PA, May 2013. Chen Y and Marx A. Evaluation of linezolid use at Inova Fairfax Hospital. Presented at the 46th Annual Midyear Clinical Meeting of the American Society of Health-System Pharmacists, New Orleans, LA, December 2011. Tanner AR and Marx A. Daptomycin utilization for gram-positive infections at a community teaching hospital. Presented at the 45th Annual Midyear Clinical Meeting of the American Society of Health- System Pharmacists, Anaheim, CA, December 2010. Kissling K, Massoud V, and Marx A. Evaluation of tigecycline use in a community teaching hospital. Presented at the 45th Annual Midyear Clinical Meeting of the American Society of Health-System Pharmacists, Anaheim, CA, December 2010. Marx A, Chee J, and Tassone D. Comparison of neonatal bilirubin levels following in utero exposure to atazanavir versus other antiretroviral agents. Presented at the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy, Boston, MA, September 2010. Jacob J, Herring A, and Steinberg J. Antibiotic consumption and infection rates in intensive care units. Presented at the 19th Annual Scientific Meeting of the Society of Healthcare Epidemiology of America, San Diego, CA, March 2009. Herring AR and Williamson JC. Principles of antimicrobial use in older adults. Clin Geriat Med. 2007;23(3):481-97. Luther VP, Smith ZE, Varela V, Williamson JC, Karchmer TB, Palavecino E, Herring A, Marion MC, and Ohl CA. Risk factors for invasive infection due to cephalosporin resistant Enterobacter spp. Presented at Wake Forest University Baptist Medical Center Resident Research Day, Winston-Salem, NC, May 2007. Herring AR, Johnson JE, Ohl CA, and Williamson JC. Correlation of vancomycin exposure and outcomes in adult patients with methicillin-resistant Staphylococcus aureus pneumonia. Presented at the 40th Annual American Society of Health-System Pharmacists Midyear Clinical Meeting, Anaheim, CA, December 2006. Presented at the 37th Annual Southeastern Residency Conference, Athens, GA, May 2004. Herring AR and Baillie GM. Analysis of perioperative antimicrobial dosing: a process improvement intervention for Surgical Infection Prevention (SIP). Presented at the 38th Annual American Society of Health-System Pharmacists Midyear Clinical Meeting, New Orleans, LA, December 2004. Presented at the 35th Annual Southeastern Residency Conference, Athens, GA, May 2004. INVITED PRESENTATIONS March 2015 UNC Grand Rounds, ASHP Advantage webcast CE. Enduring questions about S. aureus disease. ACPE accredited program. UNC Medical Center, Chapel Hill, NC. September 2014 Making Antimicrobials Safer for All Nursing Continuing Education seminar. UNC School of Nursing Center for Lifelong Learning. William and Ida Friday Center, Chapel Hill, NC. April 2012 Pediatric Grand Rounds: An Update on Vancomycin Dosing and Monitoring for the Pediatric Clinician. Accredited Physician CME. Inova Fairfax Hospital, Falls Church, VA. March 2011 Update on Urinary Tract Infections. ACPE accredited continuing education seminar. Virginia Society of Healthsystems Pharmacists 2011 Spring Seminar. Arlington, VA September 2010 September 2011 Pharmacotherapy of Central Nervous System Infections. Virginia Commonwealth University School of Pharmacy Falls Church, VA. January 2009 Pharmacology of Quinolones, Tetracyclines, and Macrolides. Emory University Physician Assistant Program. Atlanta, GA. November 2008 Update on New Antimicrobial Agents. A c c r e d i t e d P h y s i c i a n C M E . 9 t h Annual Southern Hospital Medicine Conference. Atlanta, GA. November 2008 A Hospitalist’s Guide to Antifungal Agents. A c c r e d i t e d P h y s i c i a n C M E . 9th Annual Southern Hospital Medicine Conference. Atlanta, GA. July 2008 Aminoglycosides and Vancomycin: A Practical Approach to Dosing and Monitoring. Emory University Infectious Diseases Fellows’ Didactic Course. Atlanta, GA. SELECTED PRESENTATIONS October 2010 Antifungal review for pharmacists. ACPE accredited continuing education seminar. Inova Fairfax Hospital, Falls Church, VA. September 2008 Alternative and emerging therapies for treatment of C. difficileassociated diarrhea. Case presentation for PGY-1 residents and clinical pharmacists. Emory University Hospital Midtown, Atlanta, GA. August 2008 Antimicrobial use in medical-surgical patients: Focus on Nursing Care. Emory School of Nursing Medical-Surgical Nursing Certification Course. Emory University Hospital Midtown, Atlanta, GA. June 2007 A case-based approach to antifungal agents. ACPE accredited continuing education seminar. Wake Forest Baptist Medical Center, Winston-Salem, NC. March 2007 Febrile neutropenia: what to do after antibacterial therapy fails. Lecture for Hematology/Oncology elective course. Campbell University School of Pharmacy, Buies Creek, NC. December 2006 Achieving antimicrobial synergy against methicillin-resistant Staphylococcus aureus. Department of Pharmacy Case Conference. Wake Forest University Baptist Medical Center, Winston-Salem, NC. August 2006 Antiviral agents. Infectious Diseases Fellows’ Conference. Wake Forest University Baptist Medical Center, Winston-Salem, NC. April 2005 Pharmacologic strategies for the prevention of radiocontrast-induced nephropathy. ACPE accredited continuing education seminar. Medical University of South Carolina, Charleston, SC. PROFESSIONAL AFFILIATIONS 2006-current Society of Infectious Diseases Pharmacists, member 2010, Programming Committee member 2006-current American Society for Microbiology, member 2004-current American College of Clinical Pharmacy, member AWARDS AND HONORS 2008 Emory Healthcare Clinical Certification Award 2002-2004 Howard Q. and Mescal S. Ferguson Scholar 2002 Phi Lambda Sigma Pharmaceutical Leadership Society 2002 Rho Chi Pharmaceutical Honor Society 2001-2002 Thomas G. Cornwell Scholar 1999-2004 University of North Carolina School of Pharmacy Honors Program 1998 Phi Beta Kappa