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Schematic illustration of volume available (blue) and volume excluded (pink and black) to the
center of a (A,C) small and (B,D) large spherical molecule added to a solution containing a
approximately 30% volume fraction of large spherical molecules (A,B) and the interior of a pore
shown in (square) cross-section (C,D).
Allen P. Minton J Cell Sci 2006;119:2863-2869
© The Company of Biologists Limited 2006

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