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SallyWong TheZikaVirus TheZikavirusistransmittedtopeoplethroughabitefromaninfectedmosquito.These mosquitoeslayeggsinandnearingstandingwater.Uninfectedmosquitoescanbecomeinfectedifthey happentobiteonapersonthatisalreadyinfectedwiththeZikavirus.TheZikaviruscanalsospread frommothertochildduringthemother’spregnancyandthroughsex. ProofofConceptPrototype: Iwouldfirstbuildaterrainwithafewpondsscatteredintheworld.Tostartoff,Iwillbe simulatingthespreadingoftheZikavirusthroughinfectedmosquitoesfoundinapond.Thefirst mosquitoeswillbecomeinfectedthroughacollisionwithaZikadiseaseagentfoundintheponds. BecausethemosquitoeswiththeZikavirusareusuallyfoundnearstandingwater,themosquitoeswill roamaroundnearthevicinityofthepondandwillonlybeabletomoveacertaindistancefromthe pondbeforetheymigratebacktothepond.AfterIfindthattheprototypewiththeZikadiseaseagent works,IwillbedeletedtheZikadiseaseagentandaddhumansintothesimulation.Afewinfected humanswillbeaddedintothesimulation.TheZikaviruswillbespreadbycollisionswithpeopleand mosquitoes.Ifanuninfectedmosquitobitesaninfectedperson,themosquitowillbecomeinfectedand turnintoadifferentcolor.Ifaninfectedhumancollideswithanuninfectedhuman,therewillbea certainprobabilitythattheuninfectedhumanwillbecomeinfectedsincetheZikaviruscanonlybe spreadthroughcertaininteractionssuchassex,bloodtransfusion,etc.Thehumanswillalsogetinfected whentheycollidewiththeinfectedmosquitoesandwillbecomeadifferentcolortoshowinfection.If themosquitohitsthepondcolorofblue,themosquitowillstopandthenwait12days/ticks.Itwill reproduce5mosquitoesafter12days/tickshavepassed.Infectedmosquitoescaninfectother uninfectedmosquitoesiftheycollide.Themosquitoeswilldieafteraperiodoftime(stilldecidinghow longthemosquitoeshavetolive).Myagentsaremosquitoesandhumans(uninfectedandinfected).I willknowit’sworkingifwhenthemosquitohitsthepondcolorofblue,itwillstopandreproduce5 mosquitoesafter12days/ticks.Iwillalsoknowit’sworkingifthemosquitoeschangecoloriftheycollide withaninfectedhumanandchangecolor. AsIexpandmyproject,IwanttoadddefectstothehumansthatareinfectedwiththeZikavirus tomysimulation.Thevirusinfectionduringpregnancyisknowntocauseseriousbirthdefectscalled microcephalyandotherbraindefects.Sinceitmightnotbepossibletoaddpregnancywiththetime clockinthesimulation,IwillcreateacertainprobabilitythattheinfectedhumanswithZikawillhave defects.Theinfectedhumanswillliveuptoacertaintimeperiodbeforetheywilldiesincethereis currentlynocurefortheZikavirus.Iplanonkeepingagraphthatshowsthosethatareinfectedwith ZikaandthosethatarenotinfectedwithZika.Ialsoplantohaveaclocktomeasurethetimeofthe simulation. Simulation:HowtheZikaVirusspreadstohumansovertime Goal:TodemonstratethespreadoftheZikavirustopeoplethroughmosquitoesfoundaroundponds. Agents:Mosquitoes,Humans Behaviors:Themosquitoeswillbeattractedtohumansandhumanswilltrytostrayaway/protect themselvesfromthemosquitoesbybeingabletomoveinadifferentdirectionwhentheyareclosetoa mosquito.