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Name: ________________________ Block: ________ Epigentics WEBquest http://learn.genetics.utah.edu/content/epigenetics/ What is Epigenetics? The Epigenome at a Glance -1. Describe the physical state of the genome (tightly wrapped or relaxed) when genes are inactive. 2. Describe the physical state of the genome when genes are active? Gene Control 3. When a gene is active – are there many or few methyl molecules attached to the gene? 4. When a gene is active – are there many or few mRNA transcripts? 5. When a gene is inactive – describe the amount of methyl molecules and the mRNA transcripts? The Epigenome Learns from its Experiences 6. True or False – Cell signals play a role in shaping gene expression only during development. 7. What molecule is primarily responsible for carrying cell signals to DNA? 8. Are epigenetic tags passed to daughter cells? Epigenetics and Inheritance 9. In three to four sentences, explain how parents have a role in shaping the epigenome. Identical Twins: Pinpointing environmental impact on the epigenome 10. Often, the physical characteristics of genetically identical twins become increasingly different as they are, even at the molecular level. Explain why this is so (use the terms environment and epigenome in your answer) 11. Name 3-4 environmental factors that influence the epigenome. 12. What is an imprinted gene? Nutrition & the Epigenome 13. Explain how the food we eat affects gene expression 14. Can the diets of parents affect their offspring’s epigenome?