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Name: ____________________________
Date: _________
PAP Molecular Genetic and Biotechnology Test Review
Period: ________
1. DNA TAC CGC TCC GCC GTC GAC ACT
mRNA _____________________________________________
AA
_____________________________________________
2. Circle the correct suspect and fill in the blanks
This technique to the right is done through ___________________ and this is known
as _________________
3. Put the events of genetic expression in the correct order. (Protein-RNA-Genetic Expression-DNA-Amino Acid)
___________________________________________________________________________________
4. When there is a mutation in the gamete of an organism, where will it be most likely transferred to?
_________________________
5. What is selective breeding and give an example.
__________________________________________________________________________________________________
__________________________________________________________________________________________________
6. If a gene that expresses a color is inserted into the DNA of another organism, how can a scientist determine if the
gene is transcribed and translated? __________________________________________
7. Scientist search genome-wide data bases to find genetic variations associated with common diseases such as cancer
and diabetes. Scientist must have blood samples or cheek swabs from people because these cells contain –
half the set of DNA
or
a complete set of DNA
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8. What can be determined by examining the karyotype of the individual to the
right? ____________________________________________________________
9. Genome maps provide DNA sequences of chromosomes. Scientists can compare the genome of two species. What
can scientists determine by comparing the two genomes?
____________________________________________________________________________________
10. If a disease is inherited and passed to the offspring, what can be concluded about this disease (choose a or b)?
a. Familial Alzheimer’s disease (FAD) is the result of a genetic change in one or more chromosomes
b. Familial Alzheimer’s disease (FAD) affects only the genes of middle aged people
11.
a. What process is shown in X? _______________________
b. What process is shown in Y? _______________________
c. What process is shown in Z? _______________________
12. How does DNA in cells determine an organism’s complex traits?
________________________________________________________________________________________________
13. What is the purpose of the cellular process depicted?
_________________________________________________________________________________________________
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Matching; Match the correct mutation with the correct diagram
14. _____ Duplication Mutation
15. _____ Inversion Mutation
16. _____ Translocation Mutation
17. _____ Deletion Mutation
A
B
C
D
18. What is the mRNA sequence transcribed from this segment?
DNA TAC GCC GTC GAC ACT
CGC
mRNA ____________________________________
19. DNA segment is changed from TTGCCA to TTGGCCA. This is a(n) ____________________ mutation.
20. DNA segment is changed from TTGCCA to TAGCCA. This is a(n) _____________________mutation.
21. What causes a frameshift mutation? _________________________________________________________________
22. Explain how an insertion mutation would affect a sequence of DNA?
__________________________________________________________________________________________________
23. In 1952 Rosalind Franklin took the x-ray photograph shown below, which gave the world its first look at DNA. What
did scientist gain knowledge of by studying the photograph? ________________________________________________
Matching: Match the correct mutation with the definition
A. Silent mutation (point mutation)
24. _____Mutation that results from a change in a single nucleotide.
25. _____Mutation from the deletion of a single nucleotide.
26. _____Mutation from the insertion of single nucleotide.
B. Missense mutation (point mutation)
C. Nonsense mutation (point mutation)
D. Deletion mutation (frameshift mutation)
27. _____Mutation where the amino acid does not change.
AB. Substitution mutation (point mutation)
28. _____Mutation when one amino acid is changed.
BC. Insertion mutation (frameshift
mutation)
29. _____Mutation when there is a premature stop signal.
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