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Transcript
EMBO ER Conference Short Talks
Oct 4th, Monday
Translocation
Salomé Calado Botelho
Comparison of transmembrane domain recognition between Sec61 translocon and TIM23
complex
Authors: Salomé Calado Botelho, Marie Österberg, Hyun Kim, Gunnar von Heijne
ER Associated Degradation:
Pedro Carvalho
Retro-translocation of a Misfolded Luminal ER Protein by the Ubiquitin-ligase Hrd1p
Authors: Pedro Carvalho, Ann Marie Stanley, Tom Rapoport
Glycosylation
Veit Goder
Protein O-mannosyltransferases participate in ER protein quality control by diverting proteins from
ER export to ER-associated protein degradation (ERAD)
Authors: Veit Goder, Alejandro Melero
Oct 5th, Tuesday
Disulfide Bond and Other Modifications:
Robert Gauss
A complex of Pdi1p and Htm1p initiates clearance of unfolded glycoproteins from the endoplasmic
reticulum
Authors: Robert Gauss, Kazue Kanehara, Pedro Carvalho, Davis T.W. Ng, Markus Aebi
Proteomics/High Throughput Approaches
Michael Bassik
Exploring the regulation of protein homeostasis using genetic interaction maps
Authors: Michael Bassik, Martin Jonikas, Martin Kampmann, L. Stirling Churchman, Robert Jan
Lebbink, Weronika Patena, Michael McManus, Maya Schuldiner, Jonathan Weissman
October 6th, Wednesday
Ion Homeostasis
Éva Margittai1
Hydrogen peroxide formation in the endoplasmic reticulum – double edge sword in oxidative
protein folding
Authors: Éva Margittai, Roberto Sitia, Gábor Bánhegyi
UPR (PLEASE NOTICE THERE ARE THREE TALKS HERE)
Maho Niwa
ER stress surveillance response
Authors: Anna Babour, Alicia Bicknell, Joel Tourtellotte, Maho Niwa
AND
Yair Argon
Genetic ablation of GRP94 or mutants with reduced activity profoundly affect animal growth,
because of decreased capacity to support production of Insulin-like Growth Factors
Authors: Yair Argon, Olga Ostrovsky, Davide Eletto, Michal Marzec, Gil Atzmon, Adda Grimberg
AND
John Christianson
Defining the functional complexes of mammalian ERAD
Authors: John C. Christianson, James A. Olzmann, Thomas A. Shaler, Mathew E. Sowa, Eric J.
Bennett, Caleb M. Richter, Ryan E. Tyler, Ethan J. Greenblatt, J. Wade Harper, Ron R. Kopito
Chaperones and Folding
Kalle Gehring
Structural insights into the function of the P-domains of lectin chaperones
Authors: Kalle Gehring, Guennadi Kozlov
October 7th, Thursday
Trafficking
Manuel Muñiz
The yeast p24 complex regulates GPI-anchored protein ER exit through a quality control function
Guillaume A. Castillon, Auxiliadora Aguilera-Romero, Sharon Epstein, Javier Manzano, Kentaro
Kajiwara, Kouichi Funato, Reika Watanabe, Howard Riezman, Manuel Muñiz
Architecture of ER
Dan Zhang
The cortical ER network limits the permissive zone for actomyosin ring assembly
Authors: Dan Zhang, Aleksandar Vjestica and Snezhana Oliferenko
ER in Development and Disease
Markus Zettl
Rhomboid family pseudoproteases exploit the ER quality control machinery to control intercellular
signalling
Authors: Markus Zettl, Colin Adrain, Kvido Strisovsky and Matthew Freeman